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Azido-PEG4-Val-Cit-PAB-OH

Azido-PEG4-Val-Cit-PAB-OH Structure
Azido-PEG4-Val-Cit-PAB-OH structure
CAS No.
2055024-64-9
Chemical Name:
Azido-PEG4-Val-Cit-PAB-OH
Synonyms
N3-PEG4-Val-Cit-PAB;Azido-PEG4-Val-Cit-PAB-OH;1-azido-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-3,6,9,12-tetraoxapentadecan-15-amide
CBNumber:
CB03373574
Molecular Formula:
C29H48N8O9
Molecular Weight:
652.75
MDL Number:
MFCD29918229
MOL File:
2055024-64-9.mol
MSDS File:
SDS
Last updated:2026-05-11 19:39:08
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Azido-PEG4-Val-Cit-PAB-OH Properties

form Solid
color White to off-white

Azido-PEG4-Val-Cit-PAB-OH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114399 Azido-PEG4-Val-Cit-PAB-OH ≥98% 2055024-64-9 50mg $250 2026-06-04 Buy
ChemScene CS-0114399 Azido-PEG4-Val-Cit-PAB-OH ≥98% 2055024-64-9 100mg $380 2026-06-04 Buy
BroadPharm bp-23207 Azido-PEG4-Val-Cit-PAB-OH 98% 2055024-64-9 100MG $350 2026-05-24 Buy
BroadPharm bp-23207 Azido-PEG4-Val-Cit-PAB-OH 98% 2055024-64-9 250MG $560 2026-05-24 Buy
BroadPharm bp-23207 Azido-PEG4-Val-Cit-PAB-OH 98% 2055024-64-9 500MG $980 2026-05-24 Buy
Product number Packaging Price Buy
CS-0114399 50mg $250 Buy
CS-0114399 100mg $380 Buy
bp-23207 100MG $350 Buy
bp-23207 250MG $560 Buy
bp-23207 500MG $980 Buy

Azido-PEG4-Val-Cit-PAB-OH Chemical Properties, Uses, Production

Description

Azido-PEG4-Val-Cit-PAB-OH is a cleavable peptide linker. The Val-Cit will specifically be cleaved by Cathepsin B. Azido group enable click chemistry with DBCO, BCN or other Alkyne group. PEG spacer increases aqueous solubility.

Uses

Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Protease Cleavable Linker; PEGs; Cleavable Linker

References

[1] Dan N, et al. Antibody-Drug Conjugates for Cancer Therapy: Chemistry to Clinical Implications. Pharmaceuticals (Basel). 2018 Apr 9;11(2). pii: E32. DOI:10.3390/ph11020032
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG4-Val-Cit-PAB-OH Preparation Products And Raw materials

Raw materials

Preparation Products

Azido-PEG4-Val-Cit-PAB-OH Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nanchang Tianzhen Biotechnology Co., Ltd 13758194781 13173652190 522013271@qq.com China 2447 58
csynbio 15051477682 changming.pan@csynbio.com China 245 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39999 58
Affinity（Wuhan）Ltd. 15841022315 sales@affinitytech.cn China 2980 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Supplier Advantage
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Xi'an Confluore Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanchang Tianzhen Biotechnology Co., Ltd 58
csynbio 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Affinity（Wuhan）Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Latest Price from Azido-PEG4-Val-Cit-PAB-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Azido-PEG4-Val-Cit-PAB-OH pictures 2026-05-11 Azido-PEG4-Val-Cit-PAB-OH
2055024-64-9
 $30.00 10g TargetMol Chemicals Inc.
Azido-PEG4-Val-Cit-PAB-OH pictures 2025-06-07 Azido-PEG4-Val-Cit-PAB-OH
2055024-64-9
 250mg >95.00% 250mg Xian confluore Biological Technology Co., Ltd.

2055024-64-9 (Azido-PEG4-Val-Cit-PAB-OH) Related Search:

Azido-PEG5-hydrazide Azido-PEG5-acid 1-Azidohexaethylene Glycol Azide-PEG5-t-butyl ester t-Boc-N-Amido-PEG4-Azide
Azido-PEG3-Val-Cit-PAB-OH

1of2

Azido-PEG4-Val-Cit-PAB-OH N3-PEG4-Val-Cit-PAB 1-azido-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-3,6,9,12-tetraoxapentadecan-15-amide 2055024-64-9 C29H48N8O9 ADC LINKER