PSMA-11
- CAS No.
- 1366302-52-4
- Chemical Name:
- PSMA-11
- Synonyms
- PSMA11;DKFZ-PSMA-11;PSMA-HBED-CC;PSMA-11 trifluoroacetate;HBED-CC-PSMA(1366302-52-4);1366302-52-4/2412149-32-5(TFA);HBED-CC-PSMA|||Psma-hbed-CC|||PSMA11;4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxypheny;4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amin;(3S,7S)-22-(3-(((2-((5-(2-carboxyethyl)-2-hydroxybenzyl)(carboxymethyl)amino)ethyl)(carboxymethyl)amino)methyl)-4-hydroxyphenyl)-5,13,20-trioxo-4,6,12,19-tetraazadocosane-1,3,7-tricarboxylic acid
- CBNumber:
- CB03376005
- Molecular Formula:
- C44H62N6O17
- Molecular Weight:
- 946.99308
- MDL Number:
- MFCD29767877
- MOL File:
- 1366302-52-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | -20°C, protect from light |
|---|---|
| solubility | To be determined:100.0(Max Conc. mg/mL);105.6(Max Conc. mM) |
| form | Solid |
| color | White to off-white |
| InChIKey | QJUIUFGOTBRHKP-DPMCXAKDNA-N |
| SMILES | C(C(O)=O)C[C@@H](C(O)=O)NC(=O)N[C@H](C(O)=O)CCCCNC(=O)CCCCCNC(=O)CCC1=CC=C(O)C(CN(CCN(CC2=CC(CCC(O)=O)=CC=C2O)CC(O)=O)CC(O)=O)=C1 |&1:5,13,r| |
| FDA UNII | 9AG41L3AOQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
PSMA-11 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 42984 | PSMA11 ≥98% | 1366302-52-4 | 1mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 42984 | PSMA11 ≥98% | 1366302-52-4 | 5mg | $300 | 2026-04-30 | Buy |
| Cayman Chemical | 42984 | PSMA11 ≥98% | 1366302-52-4 | 10mg | $545 | 2026-04-30 | Buy |
| Cayman Chemical | 42984 | PSMA11 ≥98% | 1366302-52-4 | 25mg | $1089 | 2026-04-30 | Buy |
| Biosynth | REC30252 | PSMA-11 | 1366302-52-4 | 1mg | $239.25 | 2026-06-05 | Buy |
PSMA-11 Chemical Properties,Uses,Production
Description
PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer.
Uses
The prostate-specific membrane antigen (PSMA) has received increased consideration during the past few years as an excellent target for both imaging and therapy of prostate cancer. After many years of outstanding preclin.
References
[1] Demirci E, et al. Normal distribution pattern and physiological variants of 68Ga-PSMA-11 PET/CT imaging. Nucl Med Commun. 2016 Nov;37(11):1169-79.
[2] Eder M, et al. 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging[J]. Bioconjugate chemistry, 2012, 23(4): 688-697.
[3] Bois F, et al. [68Ga] Ga-PSMA-11 in prostate cancer: a comprehensive review[J]. American Journal of Nuclear Medicine and Molecular Imaging, 2020, 10(6): 349.
[4] ANDREI GAFITA. qPSMA: Semiautomatic Software for Whole-Body Tumor Burden Assessment in Prostate Cancer Using 68Ga-PSMA11 PET/CT.[J]. Journal of Nuclear Medicine, 2019, 60 9: 1277-1283. DOI:10.2967/jnumed.118.224055.
PSMA-11 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Hangzhou Baige Pharmaceutical Technology Co. , Ltd. | 0571-85350119 15888826472 | 15888826472@163.com | China | 2728 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2447 | 58 |
| Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 15888826472 | bptsales@163.com | China | 3832 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
| YangZhou Ruihong Biotech Co., Ltd. | 0514-015380367604 15380367604 | sales@ruibobiotech.com | China | 509 | 55 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. | 027-65388397 18164111589 | 3321478047@qq.com | China | 2002 | 55 |
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