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1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol structure

CAS No.: 1394121-05-1

Chemical Name:: 1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol

Synonyms: 181525;GNE-2861;GNE 2861 ，E2380;GNE 2861, 10 mM in DMSO;GNE-2861; GNE 2861; GNE2861.;p21 activated kinases,inhibit,Inhibitor,PAK,GNE 2861,GNE-2861,GNE2861;1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol;1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol;1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol;Cyclohexanol, 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]-

CBNumber:: CB03380132

Molecular Formula:: C22H26N6O2

Molecular Weight:: 406.48

MDL Number:

MOL File:: 1394121-05-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

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1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Properties

storage temp.	Store at -20°C
solubility	DMSO:82.83(Max Conc. mg/mL);203.77(Max Conc. mM) Ethanol:40.65(Max Conc. mg/mL);100.0(Max Conc. mM)
form	A solid
color	White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29458	GNE-2861 ≥98%	1394121-05-1	5mg	$334	2026-04-30	Buy
Biosynth	UFC12105	GNE 2861	1394121-05-1	25mg	$1345.25	2026-06-05	Buy
Biosynth	UFC12105	GNE 2861	1394121-05-1	50mg	$1871	2026-06-05	Buy
ChemScene	CS-0012111	GNE 2861 98.97%	1394121-05-1	5mg	$184	2026-06-04	Buy
ChemScene	CS-0012111	GNE 2861 98.97%	1394121-05-1	10mg	$292	2026-06-04	Buy

Product number	Packaging	Price	Buy
29458	5mg	$334	Buy
UFC12105	25mg	$1345.25	Buy
UFC12105	50mg	$1871	Buy
CS-0012111	5mg	$184	Buy
CS-0012111	10mg	$292	Buy

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Chemical Properties, Uses, Production

Biological Activity

GNE 2861 is a PAK inhibitor with selectivity for group II. It inhibits PAK4, PAK5 and PAK6 with IC50 values of 7.5, 36 and 126 nM, respectively.

in vitro

GNE-2861 is compound 4 from the reference.

target

IC50: 7.5 nM (PAK4), 36 nM (PAK5), 126 nM (PAK6)

storage

Store at -20°C

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Suppliers

Global Suppliers ( 45)

Supplier	Tel	Email	Country	ProdList	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	17702719238	sales@sun-shinechem.com	China	1197	64
ChemShuttle, Inc.	0510-83588313-811 18800520310	sales@chemshuttle.com	China	2999	62
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4859	55
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Jiaxing Deyi Chemical Co., Ltd.	86-0573-85866609 18367600069	945717149@qq.com	China	9507	58
Wuhan Sun-shine Bio-technology Corporation Limited	+86-027-6552-2453	sales@sun-shinechem.com	China	725	58
Tianjin heowns Biochemical Technology Co., Ltd.	400-6387771-6039 18920764717	sales@heowns.com	China	24650	60

Supplier	Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	64
ChemShuttle, Inc.	62
BOC Sciences	65
Shanghai Lollane Biological Technology Co.,Ltd.	55
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Jiaxing Deyi Chemical Co., Ltd.	58
Wuhan Sun-shine Bio-technology Corporation Limited	58
Tianjin heowns Biochemical Technology Co., Ltd.	60

View Latest Price from 1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	GNE 2861 1394121-05-1	$36.00-79.00		99.07%	10g	TargetMol Chemicals Inc.

GNE 2861
1394121-05-1
$36.00-79.00
99.07%
TargetMol Chemicals Inc.

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Spectrum

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol(1394121-05-1)¹HNMR

1394121-05-1 (1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol) Related Search:

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol IPA-3 GNE-493 GNE 477 GNE-490

5-(6-(3-Methoxyoxetan-3-yl)-4-Morpholinothieno[3,2-d]pyriMidin-2-yl)pyriMidin-2-aMine

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1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol 1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol GNE-2861; GNE 2861; GNE2861. 1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol 181525 GNE-2861 Cyclohexanol, 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]- p21 activated kinases,inhibit,Inhibitor,PAK,GNE 2861,GNE-2861,GNE2861 1-((1-(2-Aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexan-1-ol GNE 2861, 10 mM in DMSO GNE 2861 ，E2380 1394121-05-1 APIS