Secoisolariciresinol diglucoside
- CAS No.
- 257930-74-8
- Chemical Name:
- Secoisolariciresinol diglucoside
- Synonyms
- (S,S)-SDG;(S,S)-Secoisolariciresinol diglucoside;Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside;β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-
- CBNumber:
- CB03383971
- Molecular Formula:
- C32H46O16
- Molecular Weight:
- 686.7
- MDL Number:
- MFCD03427692
- MOL File:
- 257930-74-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Secoisolariciresinol diglucoside 99.94% | CS-7895 | 5mg | $96 |
| Secoisolariciresinol diglucoside 99.94% | CS-7895 | 10mg | $168 |
| Secoisolariciresinol diglucoside 99.94% | CS-7895 | 25mg | $336 |
| Secoisolariciresinol diglucoside 99.94% | CS-7895 | 50mg | $468 |
| Secoisolariciresinol diglucoside 99.94% | CS-7895 | 100mg | $804 |
Secoisolariciresinol diglucoside price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7895 | Secoisolariciresinol diglucoside 99.94% | 257930-74-8 | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-7895 | Secoisolariciresinol diglucoside 99.94% | 257930-74-8 | 10mg | $168 | 2021-12-16 | Buy |
| ChemScene | CS-7895 | Secoisolariciresinol diglucoside 99.94% | 257930-74-8 | 25mg | $336 | 2021-12-16 | Buy |
| ChemScene | CS-7895 | Secoisolariciresinol diglucoside 99.94% | 257930-74-8 | 50mg | $468 | 2021-12-16 | Buy |
| ChemScene | CS-7895 | Secoisolariciresinol diglucoside 99.94% | 257930-74-8 | 100mg | $804 | 2021-12-16 | Buy |
Secoisolariciresinol diglucoside Chemical Properties,Uses,Production
Uses
Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects[1][2].
Biological Activity
Secoisolariciresinol diglucoside ((S,S)-SDG), the major lignan in whole wheat flaxseed, has anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, anti-obesity, hypolipidemic and neuroprotective effects.
in vitro
Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.
in vivo
Secoisolariciresinol diglucoside (4 mg/mouse; a single po) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.
| Animal Model: < /td> | Hand feeding mice (10 weeks old, male) are injected with TNFα |
| Dosage: | 4 mg/mouse |
| Administration: | Po 2 h before ic administration of TNFα |
| Result: | Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%. |
References
[1] Mishra OP, et al. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8. DOI:10.1016/j.bmcl.2013.07.062
[2] Rom S, et, al. Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation. J Neuroinflammation. 2018 Jan 27;15(1):25. DOI:10.1186/s12974-018-1065-0
Secoisolariciresinol diglucoside Preparation Products And Raw materials
Raw materials
Preparation Products
Secoisolariciresinol diglucoside Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5645 | 65 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 021-61312847 13636370518 | shyysw007@163.com | China | 5000 | 60 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7777 | 56 |
| Chengdu Alfa Biotechnology Co.,Ltd. | 028-028-85142057 19983342022 | 3591697873@qq.com | China | 1963 | 58 |
| Shanghai Bohu Biotechnology Co., LTD | 021-57763112 13585886131 | 3004987436@qq.com | China | 9692 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
| Beijing PUXI Technology Co., Ltd | 400-8087372 13161114455 | puxi_sale@qq.com | China | 4995 | 58 |
