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L-Selectride

L-Selectride Structure
L-Selectride structure
CAS No.
38721-52-7
Chemical Name:
L-Selectride
Synonyms
L-selectride;LITHIUM TRI-SEC-BUTYLBOROHYDRIDE;L-SELECTRIDE(R);LITHIUM TRIISOBUTYLHYDROBORATE;l-selectride solution;lithium tri-sec-butylhydroborate;lithium tri-sec-butylborohydride solution;LithiuM Tri-sec-butylborohydride (L-selectride), 1M in THF;Lithium tri-sec-butylhydridoborate, 1.0M solution in THF, packaged under Argon in resealable ChemSealTM bottles;1.0MinTHF
CBNumber:
CB0349017
Molecular Formula:
C12H28B.Li
Molecular Weight:
190.1
MDL Number:
MFCD00011708
MOL File:
38721-52-7.mol
MSDS File:
SDS
Last updated:2026-08-13 15:01:41
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L-Selectride Properties

Density 0.89 g/mL at 25 °C
Flash point 1 °F
storage temp. Flammables area
solubility Miscible with tetrahydrofuran.
form Liquid
color Colorless to yellow
Water Solubility reacts
Sensitive Moisture Sensitive
BRN 4007327
InChI InChI=1S/C12H28B.Li/c1-7-10(4)13(11(5)8-2)12(6)9-3;/h10-13H,7-9H2,1-6H3;/q-1;+1
InChIKey ACJKNTZKEFMEAK-UHFFFAOYSA-N
SMILES [Li+].[BH-](C(C)CC)(C(C)CC)C(C)CC
CAS DataBase Reference 38721-52-7(CAS DataBase Reference)
FDA UNII J471N7T23N
EPA Substance Registry System Borate(1-), hydrotris(1-methylpropyl)-, lithium, (T-4)- (38721-52-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H318-H225-H250-H260-H314-H335-H351
Precautionary statements  P310-P370+P378i-P402+P404-P210-P231+P232-P280-P305+P351+P338-P370+P378-P422
Hazard Codes  F,C
Risk Statements  11-14/15-17-34-35-19-40-37
Safety Statements  16-26-36/37/39-43-45-7/8-30
RIDADR  UN 3394 4.2/PG 1
WGK Germany  1
F  10
TSCA  TSCA listed
HazardClass  4.3
PackingGroup  II
HS Code  29319090
REACH Registrations Active
Excepted Quantities Forbidden

L-Selectride price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 178497 L-Selectride? solution 1.0M in THF 38721-52-7 8l $2290 2026-04-30 Buy
Strem Chemicals 03-1400 Lithium triisobutylhydroborate 38721-52-7 100g $77 2024-03-01 Buy
Strem Chemicals 03-1400 Lithium triisobutylhydroborate 38721-52-7 500g $308 2024-03-01 Buy
Sigma-Aldrich 178497 L-Selectride? solution 1.0M in THF 38721-52-7 100ml $95.1 2026-04-30 Buy
Sigma-Aldrich 178497 L-Selectride? solution 1.0M in THF 38721-52-7 800ml $495 2026-04-30 Buy
Product number Packaging Price Buy
178497 8l $2290 Buy
03-1400 100g $77 Buy
03-1400 500g $308 Buy
178497 100ml $95.1 Buy
178497 800ml $495 Buy

L-Selectride Chemical Properties, Uses, Production

Description

Lithium tri-sec-butylborohydride, commercially available as a one molar solution in tetrahydrofuran. It is widely used as a mild and strong reducing agent with high stereoselectivity in organic synthesis.

Features

Lithium tri-sec-butylborohydride is a new type of hydride reducing agent, which has the characteristics of strong reducing ability and high regio- and stereoselectivity.

Preparation

Lithium triisobutylhydroborate can be prepared by:In a 3000ml three-necked flask, add 1000ml of 1mol/L tri-sec-butylboron tetrahydrofuran solution, add 1000ml of 1mol/L triethylenediamine tetrahydrofuran solution simultaneously, introduce nitrogen to start stirring, put the mixture of the two in an ice-water bath After cooling to 0° C., 1000 ml of a 1 mol/L lithium aluminum hydride solution in tetrahydrofuran was slowly added dropwise to the above mixed solution with a constant pressure funnel for about 10 hours.

Physical properties

clear colourless solution

Uses

L-Selectride Solution is a reducing agent which is used in the preparation of oxygen heterocycles. Used also as a reactant in the synthesis of novel bicicyclo[3.1.0]hexane analags which may prove useful in the treatment of depression.

Uses

L-Selectride (Lithium triisobutylhydroborate) is used as a reducing agent. Reagent for: Enantioselective synthesis of a-amino acids via reduction of N-tert-butanesulfinyl ketimine esters. Diastereoselective reduction reactions. Hydride reduction of the Danishefsky pyranones. Asymmetric reductive aldol reaction of enones with a-alkoxy aldehydes. Synthesis of alkanols by carbonylation reactions.

Production Methods

L-Selectride can be readily prepared by addition of tri-sec-butylborane to a tetrahydrofuran solution of lithium aluminium hydride at room temperature. It is obtained as colorless solution in tetrahydrofuran[1].
L-Selectride preparation

References

[1] H.J.-Wang. (2009). Lithium tri-sec-Butylborohydride (l-Selectride): A Powerful and Highly StereoselectiveReducing Reagent. Synlett, 34 1, 2037–2038. https://doi.org/10.1055/S-0029-1217551

L-Selectride Preparation Products And Raw materials

Raw materials

Tri-sec-butylborane Lithium Aluminum Hydride

Preparation Products

L-Selectride Suppliers

Global Suppliers ( 212)
Supplier Tel Email Country ProdList Advantage
Cangzhou Lingang Xingchen Chemical Co.Ltd. 022-87892270 17612280360 tangjianxiang@daofuchem.com China 12 58
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Forxine Pharmaceutical Co., Ltd. 21-21-64961388 18918697718 service@forxine.com China 65 60
Infinity SCI 400-106-2016 17800804092 admin@infsci.com China 471 55
Shangqiu Huakang Zhongbang Biotechnology Co., Ltd 13011705167 3838015797@qq.com China 76 58
Gansu Junmao New Materials Science and Technology Co., Ltd. 23757385 18522062012 sales@jm-hydride.com China 17 58
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Shanghai Chemilab Biotechnology CO.,Ltd 18116465878 kmlb@kaimilaibo.com China 2414 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Supplier Advantage
Cangzhou Lingang Xingchen Chemical Co.Ltd. 58
Energy Chemical 61
Shanghai Forxine Pharmaceutical Co., Ltd. 60
Infinity SCI 55
Shangqiu Huakang Zhongbang Biotechnology Co., Ltd 58
Gansu Junmao New Materials Science and Technology Co., Ltd. 58
Shanghai Qiao Chemical Science Co., Ltd 65
Shanghai Chemilab Biotechnology CO.,Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62

Related articles

View Latest Price from L-Selectride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lithium triisobutylhydroborate pictures 2026-09-14 Lithium triisobutylhydroborate
38721-52-7
 $120.00 1g 1M solution in THF 25kg Shanghai UCHEM Inc.
Lithium tri-sec-butylborohydride pictures 2026-08-31 Lithium tri-sec-butylborohydride
38721-52-7
 100kg 1±0.02M in THF 100 tons Cangzhou Lingang Xingchen Chemical Co.,Ltd.
Lithium triisobutylhydroborate；L-SELECTRIDE(R) pictures 2026-08-28 Lithium triisobutylhydroborate；L-SELECTRIDE(R)
38721-52-7
 1KG 0.98 1000 KG Gansu Junmao New Materials Technology Co., Ltd

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