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ChemicalBook >> CAS DataBase List >>ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate

ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate

ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate Structure
ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate structure
CAS No.
5948-75-4
Chemical Name:
ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate
Synonyms
gp120-IN-1;ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate;5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo-, ethyl ester
CBNumber:
CB03521669
Molecular Formula:
C15H18N2O4S
Molecular Weight:
322.38
MDL Number:
MFCD02331148
MOL File:
5948-75-4.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01TOEG ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate 90% 5948-75-4 1mg $250 2026-05-31 Buy
aablocks AA01TOEG ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate 90% 5948-75-4 5mg $278 2026-05-31 Buy
aablocks AA01TOEG ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate 90% 5948-75-4 10mg $298 2026-05-31 Buy
aablocks AA01TOEG ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate 90% 5948-75-4 25mg $370 2026-05-31 Buy
aablocks AA01TOEG ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate 90% 5948-75-4 50mg $520 2026-05-31 Buy
Product number Packaging Price Buy
AA01TOEG 1mg $250 Buy
AA01TOEG 5mg $278 Buy
AA01TOEG 10mg $298 Buy
AA01TOEG 25mg $370 Buy
AA01TOEG 50mg $520 Buy

ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate Chemical Properties, Uses, Production

Uses

gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 μM and CC50 of 100.90 μM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells[1].

IC 50

HIV-1: 2.2 μM (IC50); HIV-1: 100.90 μM (CC50)

References

[1] Senapathi J, et al. Design, Synthesis, and Antiviral activity of 1,2,3,4-Tetrahydropyrimidine derivatives acting as novel entry inhibitors to target at "Phe43 cavity" of HIV-1 gp120. Bioorg Med Chem. 2021 Dec 15;52:116526. DOI:10.1016/j.bmc.2021.116526

ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
gp120-IN-1 pictures 2026-08-08 gp120-IN-1
5948-75-4
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • gp120-IN-1 pictures
  • gp120-IN-1
    5948-75-4
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

5948-75-4 (ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate) Related Search:

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ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo-, ethyl ester gp120-IN-1 5948-75-4