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Bispyrazolone

Bispyrazolone structure

CAS No.: 7477-67-0

Chemical Name:: Bispyrazolone

Synonyms: NSC 37393;NSC 401001;Bispyrazolone;edaravone diMer;Bispyrazolone, GR;Bispyrazolone, 98+%;Edaravone impurity Ⅰ;Edaravone IMpurity IV;LABOTEST-BB LT00008461;Edaravone DiMer IMpurity

CBNumber:: CB0360601

Molecular Formula:: C20H18N4O2

Molecular Weight:: 346.38

MDL Number:: MFCD00020765

MOL File:: 7477-67-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:48:19

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Bispyrazolone Properties

Melting point	355 °C
Boiling point	481.12°C (rough estimate)
Density	1.31
refractive index	1.6620 (estimate)
storage temp.	Refrigerator
solubility	formic acid: 50 mg/mL, clear, yellow
pka	2.15±0.70(Predicted)
form	crystalline
color	tan
BRN	572787
InChI	1S/C20H18N4O2/c1-13-17(19(25)23(21-13)15-9-5-3-6-10-15)18-14(2)22-24(20(18)26)16-11-7-4-8-12-16/h3-12,17-18H,1-2H3
InChIKey	FORCWSNQDMPPOC-UHFFFAOYSA-N
SMILES	CC1=NN(c2ccccc2)C(=O)C1C3C(C)=NN(c4ccccc4)C3=O
CAS DataBase Reference	7477-67-0(CAS DataBase Reference)
FDA UNII	P77NZ4BRC7
EPA Substance Registry System	[4,4'-Bi-3H-pyrazole]-3,3'-dione, 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl- (7477-67-0)
UNSPSC Code	41116105
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H317

Precautionary statements

P280g-P302+P352a-P321-P333+P313-P501a-P261-P272-P280-P302+P352+P333+P313+P363-P501

PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes

Risk Statements

Safety Statements

36/37

WGK Germany

TSCA

TSCA listed

HS Code

29331990

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

Bispyrazolone price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	15156	Bispyrazolone for TLC derivatization, for the det.of cyanide, ≥98.0%	7477-67-0	5g	$56.2	2026-04-30	Buy
TCI Chemical	B0508	Bis(3-methyl-1-phenyl-5-pyrazolone) [for Determination of CN, Vitamin B12, etc] >97.0%(T)	7477-67-0	25g	$103	2026-04-30	Buy
TCI Chemical	B0508	Bis(3-methyl-1-phenyl-5-pyrazolone) [for Determination of CN, Vitamin B12, etc] >97.0%(T)	7477-67-0	250g	$570	2026-04-30	Buy
Biosynth	FB75456	Bis(3-methyl-1-phenyl-5-pyrazolone)	7477-67-0	5g	$900	2026-06-04	Buy
Biosynth	FB75456	Bis(3-methyl-1-phenyl-5-pyrazolone)	7477-67-0	2g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
15156	5g	$56.2	Buy
B0508	25g	$103	Buy
B0508	250g	$570	Buy
FB75456	5g	$900	Buy
FB75456	2g	$900	Buy

Bispyrazolone Chemical Properties,Uses,Production

Chemical Properties

off-white to cream-yellowish crystalline powder

Uses

Bispyrazolone is an impurity of Edaravone (E335000).

Uses

It is applied as a reagent for the detection and determination of cyanide. It is also used in an experimental procedure, done in order to remove linamarin in starch from cassava roots, by using plant cell wall-degrading enzymes, xylanase and cellulase. It was also used for spectrophotometric determination and quantization of urea in urine samples. It is also used in assay of cyanogenic compounds and determination of ammonia.

Bispyrazolone synthesis

Synthesis of Bispyrazolone from 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one

Bispyrazolone Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate N-Bromosuccinimide Sodium acetate trihydrate Acetic acid Phenylhydrazine

1H-Pyrazol-5-ol, 3-methyl-4-nitroso-1-phenyl- 4-bromo-3-methyl-1-phenyl-pyrazolin-5-one Edaravone 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one Ethanol

Selenium dioxide 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one

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Preparation Products

4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-1,2-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one

Bispyrazolone Suppliers

Global( 186)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	94607	76
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
future industrial shanghai co., ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Shandong Xiya Chemical Co., Ltd	57
Syntechem Co.,Ltd	57
Sichuan Kulinan Technology Co., Ltd	57

View Lastest Price from Bispyrazolone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-08	Bispyrazolone 7477-67-0	$39.00-118.00		99.40%	10g	TargetMol Chemicals Inc.
2026-08-08	Bispyrazolone 7477-67-0	$39.00-118.00		99.40%	10g	TargetMol Chemicals Inc.
2025-06-27	BISPYRAZOLONE 7477-67-0		1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

Bispyrazolone
7477-67-0
$39.00-118.00
99.40%
TargetMol Chemicals Inc.

Bispyrazolone
7477-67-0
$39.00-118.00
99.40%
TargetMol Chemicals Inc.

BISPYRAZOLONE
7477-67-0
99%
Hebei Chuanghai Biotechnology Co., Ltd

Bispyrazolone Spectrum

BISPYRAZOLONE(7477-67-0)MS BISPYRAZOLONE(7477-67-0)IR1 BISPYRAZOLONE(7477-67-0)IR2 BISPYRAZOLONE(7477-67-0)Raman

7477-67-0(Bispyrazolone)Related Search:

1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one Edaravone Impurity 14 Acetyl ketene 1H-Pyrazole, 5-methoxy-3-methyl-1-phenyl- Edaravone Impurity 26

Edaravone Impurity 5 Edaravone Impurity 8 ethyl 3-acetoxy-2-butenoate Edaravone Impurity 15 Edaravone Impurity 19

1H-Pyrazole,3-ethoxy-5-methyl-1-phenyl-(9CI) Edaravone Impurity 6 NSC4751 Edaravone 5-Oxo-1-phenyl-2-pyrazolin-3-carboxylic acid

benzenediazonium chloride 4,5-Dihydro-α,3-diMethyl-5-oxo-1-phenyl-α-sulfo-1H-pyrazole-4-acetic Acid Edaravone Impurity 11

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BIS(3-METHYL-1-PHENYL-5-PYRAZOLONE) BIS(1-PHENYL-3-METHYL-5-PYRAZOLONE) LABOTEST-BB LT00008461 4,4'-BIS(3-METHYL-1-PHENYL-5-PYRAZOLONE) 4,4'-BIS(1-PHENYL-3-METHYL-5-PYRAZOLONE) 3,3-DIMETHYL-1,1-DIPHENYL-(4,4-BI-2-PYRAZOLINE)-5,5-DIONE 3,3'-DIMETHYL-1,1'-DIPHENYL-[4,4'-BI-2-PYRAZOLINE]-5,5'-DIONE 3,3'-DIMETHYL-1,1'-DIPHENYL-4,4'-BI(5-PYRAZOLONE) 3,3'-DIMETHYL-1,1'-DIPHENYL-[4,4'-BIS-2-PYRAZOLINE]-5,5'-DIONE 3,3'-DIMETHYL-1,1'-DIPHENYL-4,4'-DI-2-PYRAZOLINE-5,5'-DIONE [4,4’-bi-3h-pyrazole]-3,3’-dione,2,2’,4,4’-tetrahydro-5,5’-dimethyl-2,2’-diphe Edaravone Impurity 16 (Bis-pyrazolone) 4,4'-Bis(1-phenyl-3-methyl-5-pyrazolone/3,3'-Dimethyl-1,1'-diphenyl[4,4'-bi-1H-pyrazole] Edaravone Impurity Ⅰ:2,2',4,4'-Tetrahydro-5,5'-dimethyl-2,2'-diphenyl-[4,4'-Bi-3H-pyrazole]-3,3'-dione [4,4’-bi-3H-Pyrazole]-3,3’-dione,2,2’,4,4’-tetrahydro-5,5’-dimethyl-2,2’-diphenyl- 4’-bi-3H-Pyrazole]-3,3’-dione,2,2’,4,4’-tetrahydro-5,5’-dimethyl-2,2’-diphenyl-[4 Bis(1-phenyl-3-methyl-5-pyrazo BISPYRAZOLONE, FOR THE DETECTION OF CYAN IDE 4,4'-BIS(3-METHYL-1-PHENYL-5-PYRAZOLONE)[FOR DETERMINATION OF CN, VITAMIN B12, ETC] 97+% BISPYRAZOLONE(4,4''-BIS-(3-METHYL-1-PHENYL-5-PYRAZOLONE)) 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl-[4,4'-bi-3H-Pyrazole]-3,3'-dione 3,3-DIMETHYL-1,1''-DIPHENYL[4,4''-BI-2-PYRAZOLINE]-5,5''-DIONE 98% 3,3'-Dimethyl-1,1'-diphenyl-4,4'-bi(2-pyrazolin-5-one) 3,3'-Dimethyl-1,1'-diphenyl[4,4'-bi-2-pyrazoline]-5,5'-dione,98% Bispyrazolone,3,3′-Dimethyl-1,1′-diphenyl-(4,4′-bi-2-pyrazoline)-5,5′-dione Bispyrazolone, 98+% Bis(3-Methyl-1-phenylpyrazol-5-one) NSC 37393 NSC 401001 Bispyrazolone 3,3'-Dimethyl-1,1'-diphenyl-4,4'-bi(5-pyrazolone) [for DeterMination of CN, VitaMin B12, etc] Bis(3-Methyl-1-phenyl-5-pyrazolone) edaravone diMer edaravone related substance A Edaravone DiMer IMpurity 3,3'-diMethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazole]-5,5'(4H,4'H)-dione 4,4'-Bis(3-Methyl-1-phenyl-5-pyrazolone), for analysis Edaravone IMpurity IV Bis(3-methyl-1-phenyl-5-pyrazolone) [for Determination of CN, Vitamin B12, etc] 3,3'-Dimethyl-1,1'-diphenyl[4,4'-bi-2-pyrazoline]-5,5'-dione Bis-pyrazolone Bis(3-methyl-1-phenyl-5-pyrazolone) 4,4'-Bis(3-methyl-1-phenyl-5-pyrazolone), 97%, for analysis Edaravone Impurity IV (Bispyrazolone) Bis(3-methyl-1-phenyl-5-pyrazolone)[forDeterminationofCN,VitaminB12,etc]> Bispyrazolone, GR Edaravone Impurity Ⅰ:2,2’,4,4’-Tetrahydro-5,5’-dimethyl-2,2’-diphenyl-[4,4’-Bi-3H-pyrazole]-3,3’-dione 5-methyl-4-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenyl-4H-pyrazol-3-one Bispyrazolone, Technical, Fisher Chemical Bis(3-methyl-1-phenyl-5-pyrazolone), for Determination of CN, Vitamin B12, etc，≥ 97.0% 3,3’-Dimethyl-1,1’-diphenyl-[4,4’-bi-2-pyrazoline]-5,5’-dione 4,4’-Bis(1-phenyl-3-methyl-5-pyrazolone/3,3’-Dimethyl-1,1’-diphenyl[4,4’-bi-1H-pyrazole Edaravone impurity Ⅰ 3,3'-Dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazole]-5,5'(4H,4'H)-dione (Edaravone Impurity) 3,3'-dimethyl-1,1'-diphenyl-4,4'-bi-5-pyrazolone Bispyrazolone, 10 mM in DMSO 3,3'-Dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazole]-5,5'(4H,4'H)-dione (Edaravone Impurity) Edaravone Dimer: 5,5'-Dimethyl-2,2'-diphenyl-2,2',4,4'-tetrahydro-3H,3'H-[4,4'-bipyrazole]-3,3'-dione Bispyrazolone 7477-67-0