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2,4,5-TRIFLUOROBENZYL CHLORIDE

CAS No.
243139-71-1
Chemical Name:
2,4,5-TRIFLUOROBENZYL CHLORIDE
Synonyms
CAS:243139-71-1;Sitagliptin Impurity 70;2,4,5-TRIFLUOROBENZYL CHORIDE;2,4,5-TRIFLUOROBENZYL CHLORIDE;alpha-Chloro-2,4,5-trifluorotoluene;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
CBNumber:
CB0361981
Molecular Formula:
C7H4ClF3
Molecular Weight:
180.55
MDL Number:
MFCD00236319
MOL File:
243139-71-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:40:01

2,4,5-TRIFLUOROBENZYL CHLORIDE Properties

Boiling point 175℃
Density 1,689 g/cm3
refractive index 1.5050
Flash point 65°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color Colorless to Almost colorless
InChI InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
InChIKey JMXPOOVDUVHJRO-UHFFFAOYSA-N
SMILES C1(CCl)=CC(F)=C(F)C=C1F
CAS DataBase Reference 243139-71-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H227-H290-H314-H318
Precautionary statements  P210e-P260h-P303+P361+P353-P305+P351+P338-P501a-P210-P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P403+P235-P405-P406-P501
Hazard Codes  C,Xn
Risk Statements  34-36/37/38-20/21/22
Safety Statements  26-36/37/39-36
RIDADR  3265
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  2903998090
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
3 0

2,4,5-TRIFLUOROBENZYL CHLORIDE price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T2889 2,4,5-Trifluorobenzyl Chloride >98.0%(GC) 243139-71-1 1g $60 2026-04-30 Buy
TCI Chemical T2889 2,4,5-Trifluorobenzyl Chloride >98.0%(GC) 243139-71-1 5g $209 2026-04-30 Buy
Apolloscientific PC7113 2,4,5-Trifluorobenzyl chloride 98% 243139-71-1 25g $137 2026-06-04 Buy
Apolloscientific PC7113 2,4,5-Trifluorobenzyl chloride 98% 243139-71-1 100g $408 2026-06-04 Buy
Apolloscientific PC7113 2,4,5-Trifluorobenzyl chloride 98% 243139-71-1 500g $1428 2026-06-04 Buy
Product number Packaging Price Buy
T2889 1g $60 Buy
T2889 5g $209 Buy
PC7113 25g $137 Buy
PC7113 100g $408 Buy
PC7113 500g $1428 Buy

2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

Colorless to Almost colorless clear liquid.

Uses

2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in glucagon to improve control of blood sugar used for the treatment of type 1 diabetes, 79% of the dose excreted in the urine.

Uses

2,4,5-Trifluorobenzyl chloride is a useful research chemical.

Synthesis

On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride.

2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2,4,5-TRIFLUOROBENZYL CHLORIDE Suppliers

Global( 181)Suppliers
Supplier Tel Email Country ProdList Advantage
Qingzhou dafeng import and export Co. LTD 16773308882 927608786@qq.com China 3051 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57

View Lastest Price from 2,4,5-TRIFLUOROBENZYL CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4,5-Trifluorobenzyl chloride pictures 2026-08-25 2,4,5-Trifluorobenzyl chloride
243139-71-1
$2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2,4,5-Trifluorobenzyl chloride pictures 2026-05-18 2,4,5-Trifluorobenzyl chloride
243139-71-1
1kg 98% Hefei Lbao Physical & Chemical Science Co.,Ltd
2,4,5-TRIFLUOROBENZYL CHLORIDE pictures 2026-03-20 2,4,5-TRIFLUOROBENZYL CHLORIDE
243139-71-1
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd

2,4,5-TRIFLUOROBENZYL CHLORIDE Spectrum

2,4,5-TRIFLUOROBENZYL CHLORIDE 2,4,5-TRIFLUOROBENZYL CHORIDE Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI) 1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene Sitagliptin Impurity 70 Benzene, 1-(chloromethyl)-2,4,5-trifluoro- alpha-Chloro-2,4,5-trifluorotoluene CAS:243139-71-1 243139-71-1 C7H4CIF3 Fluorine series HALOMETYL Miscellaneous