2,4,5-TRIFLUOROBENZYL CHLORIDE
- CAS No.
- 243139-71-1
- Chemical Name:
- 2,4,5-TRIFLUOROBENZYL CHLORIDE
- Synonyms
- CAS:243139-71-1;Sitagliptin Impurity 70;2,4,5-TRIFLUOROBENZYL CHORIDE;2,4,5-TRIFLUOROBENZYL CHLORIDE;alpha-Chloro-2,4,5-trifluorotoluene;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
- CBNumber:
- CB0361981
- Molecular Formula:
- C7H4ClF3
- Molecular Weight:
- 180.55
- MDL Number:
- MFCD00236319
- MOL File:
- 243139-71-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 175℃ |
|---|---|
| Density | 1,689 g/cm3 |
| refractive index | 1.5050 |
| Flash point | 65°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | clear liquid |
| color | Colorless to Almost colorless |
| InChI | InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2 |
| InChIKey | JMXPOOVDUVHJRO-UHFFFAOYSA-N |
| SMILES | C1(CCl)=CC(F)=C(F)C=C1F |
| CAS DataBase Reference | 243139-71-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H227-H290-H314-H318 | |||||||||
| Precautionary statements | P210e-P260h-P303+P361+P353-P305+P351+P338-P501a-P210-P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P403+P235-P405-P406-P501 | |||||||||
| Hazard Codes | C,Xn | |||||||||
| Risk Statements | 34-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| RIDADR | 3265 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2903998090 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2,4,5-TRIFLUOROBENZYL CHLORIDE price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2889 | 2,4,5-Trifluorobenzyl Chloride >98.0%(GC) | 243139-71-1 | 1g | $60 | 2026-04-30 | Buy |
| TCI Chemical | T2889 | 2,4,5-Trifluorobenzyl Chloride >98.0%(GC) | 243139-71-1 | 5g | $209 | 2026-04-30 | Buy |
| Apolloscientific | PC7113 | 2,4,5-Trifluorobenzyl chloride 98% | 243139-71-1 | 25g | $137 | 2026-06-04 | Buy |
| Apolloscientific | PC7113 | 2,4,5-Trifluorobenzyl chloride 98% | 243139-71-1 | 100g | $408 | 2026-06-04 | Buy |
| Apolloscientific | PC7113 | 2,4,5-Trifluorobenzyl chloride 98% | 243139-71-1 | 500g | $1428 | 2026-06-04 | Buy |
2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
Colorless to Almost colorless clear liquid.
Uses
2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in glucagon to improve control of blood sugar used for the treatment of type 1 diabetes, 79% of the dose excreted in the urine.
Uses
2,4,5-Trifluorobenzyl chloride is a useful research chemical.
Synthesis
On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride.
2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials
2,4,5-TRIFLUOROBENZYL CHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingzhou dafeng import and export Co. LTD | 16773308882 | 927608786@qq.com | China | 3051 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
View Lastest Price from 2,4,5-TRIFLUOROBENZYL CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-08-25 | 2,4,5-Trifluorobenzyl chloride
243139-71-1
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![]() |
2026-05-18 | 2,4,5-Trifluorobenzyl chloride
243139-71-1
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd | |||
![]() |
2026-03-20 | 2,4,5-TRIFLUOROBENZYL CHLORIDE
243139-71-1
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 2,4,5-Trifluorobenzyl chloride
243139-71-1
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 2,4,5-Trifluorobenzyl chloride
243139-71-1
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-

- 2,4,5-TRIFLUOROBENZYL CHLORIDE
243139-71-1
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
243139-71-1(2,4,5-TRIFLUOROBENZYL CHLORIDE)Related Search:
1of4





