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Methyl phosphorodichloridate

CAS No.
677-24-7
Chemical Name:
Methyl phosphorodichloridate
Synonyms
Methy;METHYL DICHLOROPHOSPHATE;METHYL PHOSPHORODICHL;Methoxyphosphorylchloride;Methyl dichloridophosphate;Methyl phosphoric dichloride;dichlorophosphoryloxymethane;Methyl dichlorophosphate,97%;Methyl dichlorophosphate 85%;Methyl phosphorodichloridate
CBNumber:
CB0404615
Molecular Formula:
CH3Cl2O2P
Molecular Weight:
148.91
MDL Number:
MFCD00002068
MOL File:
677-24-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:19

Methyl phosphorodichloridate Properties

Melting point -59 °C
Boiling point 62-64 °C/15 mmHg (lit.)
Density 1.488 g/mL at 25 °C (lit.)
refractive index n20/D 1.436(lit.)
Flash point >230 °F
storage temp. 2-8°C
form clear liquid
color Colorless to Light yellow
InChI 1S/CH3Cl2O2P/c1-5-6(2,3)4/h1H3
InChIKey SNVCRNWSNUUGEA-UHFFFAOYSA-N
SMILES COP(Cl)(Cl)=O
CAS DataBase Reference 677-24-7(CAS DataBase Reference)
FDA UNII P5R9XZ7EJU
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34
Safety Statements  26-27-28-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
HS Code  2919.90.5050
HazardClass  8
PackingGroup  III
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
NFPA 704
1
0 0

Methyl phosphorodichloridate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 158216 Methyl dichlorophosphate 85% 677-24-7 25g $173 2026-04-30 Buy
TCI Chemical M0904 Methyl Phosphorodichloridate >95.0%(T) 677-24-7 5g $73 2023-06-20 Buy
TCI Chemical M0904 Methyl Phosphorodichloridate >95.0%(T) 677-24-7 25g $202 2026-04-30 Buy
Usbiological 284886 Methyl Phosphorodichloridate Asreported 677-24-7 10g $327 2026-06-03 Buy
Usbiological 284886 Methyl Phosphorodichloridate Asreported 677-24-7 25g $476 2026-06-03 Buy
Product number Packaging Price Buy
158216 25g $173 Buy
M0904 5g $73 Buy
M0904 25g $202 Buy
284886 10g $327 Buy
284886 25g $476 Buy

Methyl phosphorodichloridate Chemical Properties, Uses, Production

Chemical Properties

bp62-64℃/2kPa(15mmHg), d(4,25)1.488, nD201.4360, fp10℃. Corrosive and unstable in lake wet environments.

Uses

Methyl dichlorophosphate was used in the synthesis of:

  • 4,6-cyclic phosphate tetrasaccharide
  • 8-(2′′-hydroxyethoxy)adenosine-5′,2′′-phosphate derivative
  • analogs of (R)-1-O-hexadecyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine poly(ethylene glycol)
  • dioxaphosphorino[m,n-x]pyridines compounds

Methyl phosphorodichloridate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 98)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55

View Latest Price from Methyl phosphorodichloridate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL PHOSPHORODICHLORIDATE pictures 2026-03-20 METHYL PHOSPHORODICHLORIDATE
677-24-7
$10.00 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
METHYL PHOSPHORODICHLORIDATE pictures 2021-08-12 METHYL PHOSPHORODICHLORIDATE
677-24-7
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Methyl phosphorodichloridate pictures 2020-03-06 Methyl phosphorodichloridate
677-24-7
$8.00 1g ≥98% Career Henan Chemical Co
Methoxyphosphorylchloride Methyl dichloridophosphate (Phosphoric acid methyl) dichloride Dichloridophosphoric acid methyl ester Dichlorophosphinic acid methyl ester Methyl phosphoric dichloride DICHLOROPHOSPHORIC ACID METHYL ESTER Methyl dichlorophosphate,97% dichlorophosphoryloxymethane methyldichlorophosphate,methoxydichlo-rophosphineoxidemethylphosphorodichloride phosphoricacidmonomethylesterdichloride Phosphorodichloridic acid, methyl ester Phosphorodichloridicacid,methylester Methyl dichlorophosphate 85% Methyl dichlorophosphate,Methyl phosphorodichloridate MethylPhosphorodichloridate> METHYL PHOSPHORODICHL Methy METHYL DICHLOROPHOSPHATE Methyl phosphorodichloridate 677-24-7 CH3Cl2O2P Cl2POOCH3 DNA / RNA Synthesis Phosphorylation Phosphorylating Agents Building Blocks Phosphorus Compounds Organic Building Blocks Phosphorus Halides Biochemistry Nucleosides, Nucleotides & Related Reagents Phosphorylating and Phosphorothioating Agents Phosphorylation Protecting Agents, Phosphorylating Agents & Condensing Agents Synthetic Organic Chemistry