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2-Chloro-8-methyl-3-quinoline carboxaldehyde

2-Chloro-8-methyl-3-quinoline carboxaldehyde Structure
2-Chloro-8-methyl-3-quinoline carboxaldehyde structure
CAS No.
73568-26-0
Chemical Name:
2-Chloro-8-methyl-3-quinoline carboxaldehyde
Synonyms
AKOS AU36-M571;ASISCHEM D48938;TIMTEC-BB SBB000448;IFLAB-BB F0805-0001;2-CHLORO-8-METHYLQUINOLINE-3-CAR;2-Chloro-3-formyl-8-methylquinoline;2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDE;2-Chloro-8-methylquinoline-3-carboxaldehye;2-CHLORO-8-METHYL-QUINOLINE-3-CARBALDEHYDE;2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDEHYDE
CBNumber:
CB0405359
Molecular Formula:
C11H8ClNO
Molecular Weight:
205.64
MDL Number:
MFCD02227041
MOL File:
73568-26-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:19
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2-Chloro-8-methyl-3-quinoline carboxaldehyde Properties

Melting point 138-141 °C (lit.)
Boiling point 350.8±37.0 °C(Predicted)
Density 1.312±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka -1.29±0.50(Predicted)
form Crystalline Powder
color Yellow to yellow-brown
InChI 1S/C11H8ClNO/c1-7-3-2-4-8-5-9(6-14)11(12)13-10(7)8/h2-6H,1H3
InChIKey YPBRSXNRWFUUOE-UHFFFAOYSA-N
SMILES [H]C(=O)c1cc2cccc(C)c2nc1Cl
CAS DataBase Reference 73568-26-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29334990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

2-Chloro-8-methyl-3-quinoline carboxaldehyde price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3109 2-Chloro-8-methylquinoline-3-carboxaldehyde >98.0%(GC) 73568-26-0 1g $29 2021-12-16 Buy
TCI Chemical C3109 2-Chloro-8-methylquinoline-3-carboxaldehyde >98.0%(GC) 73568-26-0 5g $105 2021-12-16 Buy
Usbiological 270159 2-Chloro-8-methylquinoline-3-carboxaldehyde Asreported 73568-26-0 2g $333 2026-06-03 Buy
Usbiological 270159 2-Chloro-8-methylquinoline-3-carboxaldehyde Asreported 73568-26-0 5g $493 2026-06-03 Buy
Usbiological 270159 2-Chloro-8-methylquinoline-3-carboxaldehyde Asreported 73568-26-0 10g $668 2026-06-03 Buy
Product number Packaging Price Buy
C3109 1g $29 Buy
C3109 5g $105 Buy
270159 2g $333 Buy
270159 5g $493 Buy
270159 10g $668 Buy

2-Chloro-8-methyl-3-quinoline carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

Yellow to yellow-brown crystalline powder

Uses

2-Chloro-8-methylquinoline-3-carboxaldehyde acts as a reagent in the synthesis of 2-Azetidinones from 2-chloro-8-Me-3-quinolinecarbaldehyde as potential antimicrobial agents, preparation and antibacterial activity of thiazoloquinoline Schiff bases as potential antibacterial agents.

Synthesis

0.3 mol of aniline, 40 mL of glacial acetic acid and 0.4 g of zinc powder were added to a round-bottomed flask fitted with a fractionating column and a thermometer mounted at the top of the column, and the evaporated water and acetic acid were collected in a beaker. The water and acetic acid were collected in a beaker and slowly heated for 15 min and then distilled at about 105 C. When the temperature kept decreasing, the heating was stopped and the end point was reached. The reaction was poured into ice water under stirring conditions while still hot to precipitate a solid, cooled, and filtered by pumping to give crude acetanilide, which was recrystallized with water to give white, pure 2-methylacetanilide.

The product obtained in the previous step 2-methylacetanilide 0.05 mol, DMF 0.15 mol was added to a four-necked flask, fitted with a thermometer, mechanical stirrer, condenser tube, mechanical stirring in an ice bath at a temperature of less than 10 , slowly added 0.35 mol of POCl 3 dropwise, the temperature was raised to 75 after the completion of dropwise addition and stirred the reaction for 12 h, the color was changed from a light yellow oily liquid to an orange-red liquid, and the reaction was completed. After the reaction was complete, the heating was stopped, and the reactants were slowly poured into 400 mL of ice water with stirring, left to stand, and the precipitated solid was filtered, washed with water for three times, dried in air, and then recrystallized from ethyl acetate to obtain the light-yellow needle-like crystals of 2-chloro-8-methylquinoline-3-carbaldehyde. 2-Chloro-8-methylquinoline-3-carboxaldehyde prepared by acetanilide cyclosynthesis was characterized by mass spectrometry, elemental analysis, infrared, and nuclear magnetic resonance spectroscopy as follows: light yellow acicular crystals, 90% yield, mp. 150-152 C.

2-Chloro-8-methyl-3-quinoline carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

E-2-Chloro-8-methyl-3-(2-nitro)vinylquinoline 2-CHLORO-8-METHYLQUINOLINE-3-CARBONITRILE

2-Chloro-8-methyl-3-quinoline carboxaldehyde Suppliers

Global( 136)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1997 58
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Shanghai potentpharm CO.,Ltd 13524892556 sales-cn@potentpharm.com China 1011 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Tianjin heowns Biochemical Technology Co., Ltd. 57
Chengdu Forest Science and Technology Development Co., Ltd. 58
Thermo Fisher Scientific 75
Shanghai potentpharm CO.,Ltd 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75

View Lastest Price from 2-Chloro-8-methyl-3-quinoline carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE pictures 2026-08-20 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
73568-26-0
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE pictures 2021-08-12 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
73568-26-0
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE pictures 2019-12-20 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE
73568-26-0
 $1.00 1KG 99% Career Henan Chemical Co

2-Chloro-8-methyl-3-quinoline carboxaldehyde Spectrum

2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE(73568-26-0)1HNMR2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE(73568-26-0)IR

73568-26-0(2-Chloro-8-methyl-3-quinoline carboxaldehyde)Related Search:

AKOS AU36-M572 2-CHLORO-6-METHYL-3-QUINOLINE CARBOXALDEHYDE 2-Chloro-7-methoxy-quinoline-3-carbaldehyde 2-Chloro-6-methoxyquinoline-3-carbaldehyde ASISCHEM D48940
(2-CHLORO-8-METHYLQUINOLIN-3-YL)METHANOL 2-Chloro-7-(trifluoromethoxy)quinoline-3-carbaldehyde 2-chloro-8-fluoroquinoline-3-carbaldehyde 2-CHLORO-7-ETHOXY-3-QUINOLINECARBALDEHYDE 2-Chloro-7-fluoroquinoline-3-carboxaldehyde
2-Chloro-6-methoxyquinoline-3-methanol 2-Chloro-6-fluoroquinoline-3-methanol 2-Chloro-7-methoxyquinoline-3-methanol 2-Chloro-6-ethylquinoline-3-carbaldehyde 2-Chloro-6,8-dimethylquinoline-3-methanol
2-Chloro-7-(trifluoromethyl)quinoline-3-carbaldehyde 2-Chloro-8-ethyl-quinoline-3-carbaldehyde 3-Quinolinecarboxaldehyde, 2-chloro-8-(trifluoromethyl)-

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TIMTEC-BB SBB000448 AKOS AU36-M571 2-CHLORO-8-METHYL-QUINOLINE-3-CARBALDEHYDE 2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDEHYDE IFLAB-BB F0805-0001 ASISCHEM D48938 2-CHLORO-8-METHYLQUINOLINE-3-CARBOXALDE 2-Chloro-8-methylquinoline-3-carboxaldehye 2-Chloro-8-Methylquinoline-3-carboxaldehyde 98% 2-Chloro-8-methylquinoline-3-carboxaldehyde,98% 2-CHLORO-8-METHYLQUINOLINE-3-CAR JRH-03804, 2-Chloro-8-methylquinoline-3-carbaldehyde, 97% 3-Quinolinecarboxaldehyde, 2-chloro-8-methyl- 2-Chloro-3-formyl-8-methylquinoline 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE ISO 9001：2015 REACH 2-Chloro-8-methyl-3-quinoline carboxaldehyde 73568-26-0 Building Blocks Quinolines Halogenated Heterocycles Heterocyclic Building Blocks Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Quinolines QuinolinesHeterocyclic Building Blocks