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3-BROMOINDOLE-2-CARBOXYLIC ACID

CAS No.
28737-33-9
Chemical Name:
3-BROMOINDOLE-2-CARBOXYLIC ACID
Synonyms
3-BROMOINDOLE-2-CARBOXYLIC ACID;3-bromo-1H-indole-2-carboxylate;3-BroMoindole-2-carboxylic Acid, 97+%;1H-Indole-2-carboxylic acid, 3-broMo-;3-BROMOINDOLE-2-CARBOXYLIC ACID, 96+%
CBNumber:
CB0413459
Molecular Formula:
C9H6BrNO2
Molecular Weight:
240.05
MDL Number:
MFCD02710285
MOL File:
28737-33-9.mol
MSDS File:
SDS
Last updated:2026-05-27 22:38:51
Product description Number Pack Size Price
3-Bromo-1H-indole-2-carboxylic acid 90% OR111021 1g $43
3-Bromo-1H-indole-2-carboxylic acid 90% OR111021 5g $138
3-Bromo-1H-indole-2-carboxylic acid 90% OR111021 25g $403
3-Bromo-1H-indole-2-carboxylic acid 047396 500.00mg $244
3-Bromo-1H-indole-2-carboxylic acid 047396 1.00g $304
More product size

3-BROMOINDOLE-2-CARBOXYLIC ACID Properties

Melting point 185-188 °C
Boiling point 452.1±30.0 °C(Predicted)
Density 1.838±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form solid
pka 3.09±0.30(Predicted)
color Off-white
CAS DataBase Reference 28737-33-9

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xn
Risk Statements  36/37/38-21/22-36-22
Safety Statements  36/37/39-26
HazardClass  IRRITANT
HS Code  29339980

3-BROMOINDOLE-2-CARBOXYLIC ACID price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR111021 3-Bromo-1H-indole-2-carboxylic acid 90% 28737-33-9 1g $43 2026-06-04 Buy
Apolloscientific OR111021 3-Bromo-1H-indole-2-carboxylic acid 90% 28737-33-9 5g $138 2026-06-04 Buy
Apolloscientific OR111021 3-Bromo-1H-indole-2-carboxylic acid 90% 28737-33-9 25g $403 2026-06-04 Buy
Matrix Scientific 047396 3-Bromo-1H-indole-2-carboxylic acid 28737-33-9 500.00mg $244 2026-05-18 Buy
Matrix Scientific 047396 3-Bromo-1H-indole-2-carboxylic acid 28737-33-9 1.00g $304 2026-05-18 Buy
Product number Packaging Price Buy
OR111021 1g $43 Buy
OR111021 5g $138 Buy
OR111021 25g $403 Buy
047396 500.00mg $244 Buy
047396 1.00g $304 Buy

3-BROMOINDOLE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

Pinkish-beige crystalline powder

Uses

3-Bromoindole-2-carboxylic acid has been used to study the effect of Mimetic CDK9 Inhibitors on HIV-1-Activated Transcription.

Synthesis

Ethyl 3-bromoindole-2-carboxylate

91348-45-7

3-BROMOINDOLE-2-CARBOXYLIC ACID

28737-33-9

General procedure for the synthesis of 3-bromoindole-2-carboxylic acid from ethyl 3-bromoindole-2-carboxylate: ethyl 3-bromoindole-2-carboxylate (54.40 g, 203 mmol) was dissolved in ethanol (600 mL), and a solution of water (50 mL) and sodium hydroxide (20.20 g, 505 mmol) was added, and the reaction was carried out at reflux for 1 hour. After completion of the reaction, the mixture was cooled and the sodium salt of the title compound was collected by filtration. The sodium salt was dissolved in water, acidified with aqueous 3N hydrochloric acid to pH < 7 and then extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting crude product was recrystallized with ethyl acetate to give the white solid product 3-bromoindole-2-carboxylic acid (47.1 g, 88% yield). Melting point 201-203°C.

References

[1] Patent: US5684032, 1997, A
[2] Patent: WO2008/154271, 2008, A1. Location in patent: Page/Page column 88
[3] Nippon Kagaku Zasshi, 1957, vol. 78, p. 1798
[4] Chem.Abstr., 1960, p. 1487
[5] Chemische Berichte, 1923, vol. 56, p. 1024

3-BROMOINDOLE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32998 60
Accela ChemBio Inc.
+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
PT CHEM GROUP LIMITED
+86-85511178; +86-85511178 peter68@ptchemgroup.com China 35405 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Wuhan Konberd Biotech Co., Ltd
+undefined-18986093962 admin@konberdbio.com China 1377 58

View Lastest Price from 3-BROMOINDOLE-2-CARBOXYLIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-BROMOINDOLE-2-CARBOXYLIC ACID pictures 2020-01-09 3-BROMOINDOLE-2-CARBOXYLIC ACID
28737-33-9
1KG 98%;99% 500g; 1kg; 10kg; 25kg Career Henan Chemical Co
4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE pictures 2020-01-09 4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE
28737-33-9
1KG 98%;99% 500g; 1kg; 10kg; 25kg Career Henan Chemical Co

3-BROMOINDOLE-2-CARBOXYLIC ACID Spectrum

3-BROMOINDOLE-2-CARBOXYLIC ACID 3-BROMOINDOLE-2-CARBOXYLIC ACID, 96+% 1H-Indole-2-carboxylic acid, 3-broMo- 3-BroMoindole-2-carboxylic Acid, 97+% 3-bromo-1H-indole-2-carboxylate 28737-33-9