Allyltrimethylsilane
- CAS No.
- 762-72-1
- Chemical Name:
- Allyltrimethylsilane
- Synonyms
- allytrimethylsilane;3-(TRIMETHYLSILYL)PROPENE;TRIMETHYLALLYLSILANE;trimethyl-2-propenyl-Silane;DK892;CA0570;CFS-721;TMS-ALLYL;Co-Formula CFS-721;ALLYLTRIMETHYLSILANE
- CBNumber:
- CB0431082
- Molecular Formula:
- C6H14Si
- Molecular Weight:
- 114.26
- MDL Number:
- MFCD00008635
- MOL File:
- 762-72-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 84-88 °C (lit.) |
|---|---|
| Density | 0.719 g/mL at 25 °C (lit.) |
| vapor pressure | 82hPa at 25℃ |
| refractive index |
n |
| Flash point | 45 °F |
| storage temp. | 2-8°C |
| solubility | freely sol all organic solvents. |
| form | Liquid |
| Specific Gravity | 0.72 |
| color | Clear colorless |
| Water Solubility | insoluble |
| Hydrolytic Sensitivity | 2: reacts with aqueous acid |
| BRN | 906755 |
| Stability | Volatile |
| InChI | 1S/C6H14Si/c1-5-6-7(2,3)4/h5H,1,6H2,2-4H3 |
| InChIKey | HYWCXWRMUZYRPH-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)CC=C |
| LogP | 4.64 at 20℃ |
| CAS DataBase Reference | 762-72-1(CAS DataBase Reference) |
| FDA UNII | 8B84C337VF |
| NIST Chemistry Reference | Silane, trimethyl-2-propenyl-(762-72-1) |
| EPA Substance Registry System | Silane, trimethyl-2-propenyl- (762-72-1) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H315 | |||||||||
| Precautionary statements | P210-P302+P352 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | F,Xi | |||||||||
| Risk Statements | 11-36/37/38 | |||||||||
| Safety Statements | 16-26-36-23-33-7/9 | |||||||||
| RIDADR | UN 1993 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29310095 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Flam. Liq. 2 Skin Irrit. 2 |
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| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Allyltrimethylsilane price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 208264 | Allyltrimethylsilane 98% | 762-72-1 | 10g | $293 | 2026-04-30 | Buy |
| Sigma-Aldrich | 208264 | Allyltrimethylsilane 98% | 762-72-1 | 50g | $977 | 2026-04-30 | Buy |
| TCI Chemical | A0729 | Allyltrimethylsilane >98.0%(GC) | 762-72-1 | 25mL | $63 | 2026-04-30 | Buy |
| TCI Chemical | A0729 | Allyltrimethylsilane >98.0%(GC) | 762-72-1 | 250mL | $365 | 2026-04-30 | Buy |
| Usbiological | 260416 | Allyltrimethylsilane Asreported | 762-72-1 | 10g | $312 | 2026-06-03 | Buy |
Allyltrimethylsilane Chemical Properties, Uses, Production
Chemical Properties
clear colourless liquid
Uses
Allyltrimethylsilane is a general reagent to introduce allyl groups across acid chlorides, aldehydes, ketones, iminium ions, enones, and for cross-coupling with other carbon electrophiles. It is used as a reagent in HosomiSakurai reaction.
Preparation
Allyltrimethylsilane is synthesized by the reaction of trimethylchlorosilane and allylmagnesium bromide.
Application
Allyltrimethylsilane is used in the allylation of aldehydes, imines, allylic and benzylic alcohols, and chiral α-keto-amides that are derived from (S)-proline esters.
Reactions
Allyltrimethylsilane is involved as a reactant in Hosomi Sakurai reaction for allylation in the presence of Lewis acid. For example, it reacts with cyclohexanone to get 1-allylcyclohexanol. It acts as a nucleophile and is involved in Carbon-Ferrier rearrangement.
As a Carbon Nucleophile in Lewis Acid-Catalyzed Reactions.
Allyltrimethylsilane is an alkene some 10 times more nucleophilic than propene, as judged by its reactions with diarylmethyl cations.It reacts with a variety of cationic carbon electrophiles, usually prepared by coordination of a Lewis acid to a functional group, but also by chemical or electrochemical oxidation,or by irradiation in the presence of 9,10- dicyanoanthracene.
carbon to give an intermediate cation, and the silyl group is lost to create a double bond at the other terminus. Among the more straightforward electrophiles are acid chlorides (eq 1).
As a Carbon Nucleophile in Fluoride Ion-Catalyzed Reactions.
The reactions with aldehydes, ketones (eq 23),54 and α,β-unsaturated esters (eq 24)55 can also be catalyzed by fluoride ion, usually introduced as tetra-n-butylammonium fluoride (TBAF), or other silicophilic ions such as alkoxide. These reactions produce silyl ether intermediates, which are usually hydrolyzed before workup. The stereochemistry of attack on chiral ketones can sometimes be different for the Lewis acid- and fluoride ion-catalyzed reactions.
Other Reactions.
Allyltrimethylsilane reacts with some highly electrophilic alkenes, carbonyl compounds, azo compounds, and singlet oxygen to a greater or lesser extent in ene reactions that do not involve the loss of the silyl group, and hence give vinylsilanes in a solvent-dependent reaction.
Flammability and Explosibility
Flammable
Synthesis
Preparation of allyl magnesium bromide Grignard reagent: Put magnesium and anhydrous ether into a 100OL reactor, heat to about 34°C, use a metering tank to pump a certain amount of 3-bromopropylene into the reactor, control the temperature at about 54°C and react for 4 hours. Preparation of allyl trimethylsilane: After the previous reaction, pump a certain amount of trimethyl chlorosilane into the reactor, control the temperature at about 54°C and react for 4 hours. Then, atmospheric distillation, and the distillate above 45°C, is the pure product.
Purification Methods
Fractionate it through an efficient column at atmospheric pressure. If impure, dissolve it in THF, shake it with H2O (2x), dry (Na2SO4), filter and fractionate it. [Cudlin & Chvalovsky′ Collect Czech Chem Commun 27 1658 1962, Beilstein 4 IV 3927.]
Allyltrimethylsilane Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Qiao Chemical Science Co., Ltd | 021-58892003 | info@qiaochem.com | China | 6065 | 65 |
| Shanghai Ruiyi Pharmaceutical Technology Co., Ltd | 021-54711706 | sales5@ruiyitech.com | China | 225 | 58 |
| New Energy Chemicals | 0515-82159099 13770142076 | info@njuchem.com | China | 251 | 65 |
| hangzhou chemwell chemical | 0571-87824856 13676885136 | silane@163.com | China | 118 | 58 |
| Nanjing Kaitian Chemical Co., Ltd | 15951673915 | 377901895@qq.com | China | 94 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
Related articles
- Allyltrimethylsilane: Reagent Applications and Polymerization/Catalytic Reaction Studies
- Allyltrimethylsilane is a versatile reagent for introducing allyl groups for cross-coupling and used in the Hosomi?Sakurai rea....
- May 6,2025
View Latest Price from Allyltrimethylsilane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Allyltrimethylsilane
762-72-1
|
$85.00-775.00 | 1g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-09-02 | Allyltrimethylsilane
762-72-1
|
$6.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | Allyltrimethylsilane
762-72-1
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Allyltrimethylsilane
762-72-1
- $85.00-775.00
- 0.98
- Shanghai UCHEM Inc.
-
- Allyltrimethylsilane
762-72-1
- $6.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Allyltrimethylsilane
762-72-1
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
