ChemicalBook >> CAS DataBase List >>CEPHALOTAXINE

CEPHALOTAXINE

CAS No.
24316-19-6
Chemical Name:
CEPHALOTAXINE
Synonyms
(11bS,12S,14aR)-13-methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-ol;NSC 245454;NSC 128487;Cephalotaxin;Cephalotaxlen;ZINC19795976);(-)-Cephalotaxine;CEPHALOTAXINE USP/EP/BP;Cephalotaxine 24316-19-6;Cephalotaxine hydrochloride
CBNumber:
CB0435666
Molecular Formula:
C18H21NO4
Molecular Weight:
315.36
MDL Number:
MFCD21090383
MOL File:
24316-19-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-12 19:08:34
Product description Number Pack Size Price
Cephalotaxine C3641 25MG $52
Cephalotaxine C3641 100MG $155
Cephalotaxine ≥98% 36521 50mg $91
Cephalotaxine ≥98% 36521 100mg $161
Cephalotaxine ≥98% 36521 250mg $291
More product size

CEPHALOTAXINE Properties

Melting point 131-132 °C(Solv: benzene (71-43-2))
Boiling point 495.2±45.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMF: 10 mg/mL; DMSO: 12 mg/mL; Ethanol: 5 mg/mL
pka 13.30±0.40(Predicted)
form powder to crystal
color White to Orange to Green
CAS DataBase Reference 24316-19-6
FDA UNII 84MI6OYN4Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H312-H302-H332
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
RIDADR  UN 1544 6.1/PG 3
WGK Germany  3
HS Code  2939.79.0000
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
3 0

CEPHALOTAXINE price More Price(85)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3641 Cephalotaxine 24316-19-6 25MG $52 2026-04-30 Buy
TCI Chemical C3641 Cephalotaxine 24316-19-6 100MG $155 2026-04-30 Buy
Cayman Chemical 36521 Cephalotaxine ≥98% 24316-19-6 50mg $91 2026-04-30 Buy
Cayman Chemical 36521 Cephalotaxine ≥98% 24316-19-6 100mg $161 2026-04-30 Buy
Cayman Chemical 36521 Cephalotaxine ≥98% 24316-19-6 250mg $291 2026-04-30 Buy
Product number Packaging Price Buy
C3641 25MG $52 Buy
C3641 100MG $155 Buy
36521 50mg $91 Buy
36521 100mg $161 Buy
36521 250mg $291 Buy

CEPHALOTAXINE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Antiviral and antitumor agent.

Definition

ChEBI: A benzazepine alkaloid isolated from Cephalotaxus harringtonia.

Synthesis

3-Deoxy-3-oxocephalotaxine

38750-57-1

CEPHALOTAXINE

24316-19-6

Sodium borohydride (27 mg, 0.70 mmol, 40 eq.) was added to a stirred solution of (-)-cephathione (S9) (5.5 mg, 18 μmol, 1.0 eq.) in methanol (0.65 mL) at -78 °C. The resulting white mixture was continued to be stirred at -78 °C for 10 minutes, followed by a slow warming to 25 °C and stirring at this temperature for 1 hour. Upon completion of the reaction, the mixture was diluted with water (30 mL) and extracted with dichloromethane (4 x 15 mL). The organic phases were combined, dried with sodium sulfate, gravity filtered, and the filtrate was concentrated by rotary evaporation to afford the target product (-)-1 (5.2 mg, 95% yield) as a light yellow film. Thin layer chromatography (TLC) showed an Rf value of 0.08 (unfolding agent: 10% methanol/dichloromethane). The structure of the product was confirmed by 1H NMR (500 MHz, CDCl3), IR and HRMS (ESI): 1H NMR δ 6.68 (s, 1H, ArH), 6.65 (s, 1H, ArH), 5.90 (s, 2H, OCH2O), 4.93 (s, 1H, vinyl H), 4.76 (d, 1H, J = 9Hz, CH(OH )), 3.73 (s, 3H, OCH3), 3.68 (d, 1H, J = 9 Hz, ArCHCH(OH)), 3.35 (m, 1H, CH2), 3.08 (m, 1H, CH2), 2.92 (dd, 1H, J = 12, 11, 7 Hz, CH2), 2.54-2.62 (m, 2H, CH2), 2.36 (ddd, 1H, J = 14, 7Hz, CH2), 2.00 (m, 1H, CH2), 1.60-1.90 (m, 4H, CH2); IR (pure film) 3411 (broad peaks, weak), 2926 (medium), 1651 (medium), 1503 (medium), 1486 (strong), 1222 (strong) cm-1; HRMS (ESI) m/z: C18H22NO4 ([M+H]+) calculated value 316.1549, measured value 316.1559.

References

[1] Journal of the American Chemical Society, 2006, vol. 128, # 32, p. 10370 - 10371
[2] Chemistry - A European Journal, 2008, vol. 14, # 14, p. 4293 - 4306
[3] Patent: WO2009/148654, 2009, A2. Location in patent: Page/Page column 135
[4] Phytochemistry (Elsevier), 1973, vol. 12, p. 2987 - 2991

3162-29-6
24316-19-6
Synthesis of CEPHALOTAXINE from 3,4-Methylenedioxyacetophenone

CEPHALOTAXINE Preparation Products And Raw materials

Global( 241)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 4616 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202 sale02@cqherb.com CHINA 376 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from CEPHALOTAXINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CEPHALOTAXINE pictures 2026-07-11 CEPHALOTAXINE
24316-19-6
20mg 98% HPLC 100kg Changsha Staherb Natural Ingredients Co., Ltd.
CEPHALOTAXINE pictures 2026-06-30 CEPHALOTAXINE
24316-19-6
1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
ACETYLSHIKONIN pictures 2026-06-30 ACETYLSHIKONIN
24316-19-6
1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
  • CEPHALOTAXINE pictures
  • CEPHALOTAXINE
    24316-19-6
  • 98% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • CEPHALOTAXINE pictures
  • CEPHALOTAXINE
    24316-19-6
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd

CEPHALOTAXINE Spectrum

(3aR)-2-Methoxy-(3arC4,14bc)-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[b][1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-1t-ol [1S-(1a,3aS*,14b)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol NSC 128487 NSC 245454 CEPHALOTAXINE FROM CEPHALOTAXUS & Cephalotaxin Cephalotaxlen ((-)-Cephalotaxine ZINC19795976) (1S,3aR,14bβ)-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1α-ol (4R)-7,8-(Methylenebisoxy)-3,4-(trimethylene)-4β,5β-[(3S)-2-methoxy-3-hydroxypropene-1,3-diyl]-1,2,4,5-tetrahydro-3H-3-benzoazepine Cephalotaxlen (2S,3S,6R)-4-Methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15(19)-tetraen-3-ol [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-Methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol Cephalotaxine hydrochloride Cephalotaxine 24316-19-6 (1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-1-ol CEPHALOTAXINE USP/EP/BP Cephalotaxlen (ZINC19795976) (-)-Cephalotaxine Inhibitor,Cephalotaxine,ZINC 19795976,Influenza Virus,ZINC-19795976,inhibit Cephalotaxine, 10 mM in DMSO (11bS,12S,14aR)-13-methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-ol 24316-19-6 Analytical Chromatography Product Catalog Analytical Standards Chromatography Drug Standards Forensic and Veterinary Standards Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Alkaloids Chiral Reagents