CEPHALOTAXINE
- CAS No.
- 24316-19-6
- Chemical Name:
- CEPHALOTAXINE
- Synonyms
- (11bS,12S,14aR)-13-methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-ol;NSC 245454;NSC 128487;Cephalotaxin;Cephalotaxlen;ZINC19795976);(-)-Cephalotaxine;CEPHALOTAXINE USP/EP/BP;Cephalotaxine 24316-19-6;Cephalotaxine hydrochloride
- CBNumber:
- CB0435666
- Molecular Formula:
- C18H21NO4
- Molecular Weight:
- 315.36
- MDL Number:
- MFCD21090383
- MOL File:
- 24316-19-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Cephalotaxine | C3641 | 25MG | $52 |
| Cephalotaxine | C3641 | 100MG | $155 |
| Cephalotaxine ≥98% | 36521 | 50mg | $91 |
| Cephalotaxine ≥98% | 36521 | 100mg | $161 |
| Cephalotaxine ≥98% | 36521 | 250mg | $291 |
| More product size | |||
| Melting point | 131-132 °C(Solv: benzene (71-43-2)) |
|---|---|
| Boiling point | 495.2±45.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMF: 10 mg/mL; DMSO: 12 mg/mL; Ethanol: 5 mg/mL |
| pka | 13.30±0.40(Predicted) |
| form | powder to crystal |
| color | White to Orange to Green |
| CAS DataBase Reference | 24316-19-6 |
| FDA UNII | 84MI6OYN4Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H312-H302-H332 | |||||||||
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36 | |||||||||
| RIDADR | UN 1544 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2939.79.0000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
CEPHALOTAXINE price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3641 | Cephalotaxine | 24316-19-6 | 25MG | $52 | 2026-04-30 | Buy |
| TCI Chemical | C3641 | Cephalotaxine | 24316-19-6 | 100MG | $155 | 2026-04-30 | Buy |
| Cayman Chemical | 36521 | Cephalotaxine ≥98% | 24316-19-6 | 50mg | $91 | 2026-04-30 | Buy |
| Cayman Chemical | 36521 | Cephalotaxine ≥98% | 24316-19-6 | 100mg | $161 | 2026-04-30 | Buy |
| Cayman Chemical | 36521 | Cephalotaxine ≥98% | 24316-19-6 | 250mg | $291 | 2026-04-30 | Buy |
CEPHALOTAXINE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Antiviral and antitumor agent.
Definition
ChEBI: A benzazepine alkaloid isolated from Cephalotaxus harringtonia.
Synthesis
38750-57-1
24316-19-6
Sodium borohydride (27 mg, 0.70 mmol, 40 eq.) was added to a stirred solution of (-)-cephathione (S9) (5.5 mg, 18 μmol, 1.0 eq.) in methanol (0.65 mL) at -78 °C. The resulting white mixture was continued to be stirred at -78 °C for 10 minutes, followed by a slow warming to 25 °C and stirring at this temperature for 1 hour. Upon completion of the reaction, the mixture was diluted with water (30 mL) and extracted with dichloromethane (4 x 15 mL). The organic phases were combined, dried with sodium sulfate, gravity filtered, and the filtrate was concentrated by rotary evaporation to afford the target product (-)-1 (5.2 mg, 95% yield) as a light yellow film. Thin layer chromatography (TLC) showed an Rf value of 0.08 (unfolding agent: 10% methanol/dichloromethane). The structure of the product was confirmed by 1H NMR (500 MHz, CDCl3), IR and HRMS (ESI): 1H NMR δ 6.68 (s, 1H, ArH), 6.65 (s, 1H, ArH), 5.90 (s, 2H, OCH2O), 4.93 (s, 1H, vinyl H), 4.76 (d, 1H, J = 9Hz, CH(OH )), 3.73 (s, 3H, OCH3), 3.68 (d, 1H, J = 9 Hz, ArCHCH(OH)), 3.35 (m, 1H, CH2), 3.08 (m, 1H, CH2), 2.92 (dd, 1H, J = 12, 11, 7 Hz, CH2), 2.54-2.62 (m, 2H, CH2), 2.36 (ddd, 1H, J = 14, 7Hz, CH2), 2.00 (m, 1H, CH2), 1.60-1.90 (m, 4H, CH2); IR (pure film) 3411 (broad peaks, weak), 2926 (medium), 1651 (medium), 1503 (medium), 1486 (strong), 1222 (strong) cm-1; HRMS (ESI) m/z: C18H22NO4 ([M+H]+) calculated value 316.1549, measured value 316.1559.
References
[1] Journal of the American Chemical Society, 2006, vol. 128, # 32, p. 10370 - 10371
[2] Chemistry - A European Journal, 2008, vol. 14, # 14, p. 4293 - 4306
[3] Patent: WO2009/148654, 2009, A2. Location in patent: Page/Page column 135
[4] Phytochemistry (Elsevier), 1973, vol. 12, p. 2987 - 2991
CEPHALOTAXINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from CEPHALOTAXINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-11 | CEPHALOTAXINE
24316-19-6
|
20mg | 98% HPLC | 100kg | Changsha Staherb Natural Ingredients Co., Ltd. | ||
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2026-06-30 | CEPHALOTAXINE
24316-19-6
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-06-30 | ACETYLSHIKONIN
24316-19-6
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-

- CEPHALOTAXINE
24316-19-6
- 98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-

- CEPHALOTAXINE
24316-19-6
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- ACETYLSHIKONIN
24316-19-6
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
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