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ChemicalBook >> CAS DataBase List >>1,4-Di(2,2,2-trifluoroethoxy)benzene

1,4-Di(2,2,2-trifluoroethoxy)benzene

1,4-Di(2,2,2-trifluoroethoxy)benzene Structure
1,4-Di(2,2,2-trifluoroethoxy)benzene structure
CAS No.
66300-61-6
Chemical Name:
1,4-Di(2,2,2-trifluoroethoxy)benzene
Synonyms
1,4-BIS(2,2,2-TRIFLUOROETHOXY)BENZENE;Flecainide Impurity 3;Flecainide Impurity 17;1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE;Benzene, 1,4-bis(2,2,2-trifluoroethoxy)-;1,4-Bis(2,2,2-trifluoroethoxy)benzene97%;1,4-Bis(2,2,2-trifluoroethoxy)benzene 97%;1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE 66300-61-6;1,4-Bis(2,2,2-Trifluoroethoxy)-Benzene （For Flecaintde）
CBNumber:
CB0453471
Molecular Formula:
C10H8F6O2
Molecular Weight:
274.16
MDL Number:
MFCD00042272
MOL File:
66300-61-6.mol
MSDS File:
SDS
Last updated:2026-05-27 22:41:19
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1,4-Di(2,2,2-trifluoroethoxy)benzene Properties

Melting point 71-73°C
Boiling point 111-112°C/10mm
Density 1.348±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid
BRN 4464913
CAS DataBase Reference 66300-61-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  22-26-36/37/39
Hazard Note  Harmful
HS Code  2906290090
REACH Registrations Active
NFPA 704
1
2 0

1,4-Di(2,2,2-trifluoroethoxy)benzene price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC3053J 1,4-Bis(2,2,2-trifluoroethoxy)benzene ≥95% 66300-61-6 5g $82 2026-06-04 Buy
Apolloscientific PC3053J 1,4-Bis(2,2,2-trifluoroethoxy)benzene ≥95% 66300-61-6 10g $154 2026-06-04 Buy
Matrix Scientific 084979 1,4-Di-(2,2,2-trifluoroethoxy)benzene 66300-61-6 1.00g $56 2026-05-18 Buy
Matrix Scientific 084979 1,4-Di-(2,2,2-trifluoroethoxy)benzene 66300-61-6 10.00g $252 2026-05-18 Buy
Synthonix B65355 1,4-Bis(2,2,2-trifluoroethoxy)benzene >98% 66300-61-6 1g $35 2026-05-06 Buy
Product number Packaging Price Buy
PC3053J 5g $82 Buy
PC3053J 10g $154 Buy
084979 1.00g $56 Buy
084979 10.00g $252 Buy
B65355 1g $35 Buy

1,4-Di(2,2,2-trifluoroethoxy)benzene Chemical Properties, Uses, Production

Uses

1,4-Bis(2,2,2-trifluoroethoxy)benzene is useful in ligand design for Cu-Catalyzed Coupling Reactions.

Synthesis

Hydroquinone (1 eq), potassium carbonate (2.2 eq), and tetrabutylammonium bromide (0.1 eq) were dissolved in DMF, and 2,2,2-trifluoroethyl bromide (2.2 eq) was added. The mixture was stirred at 80 °C for 12 h. The reaction solution was quenched with water, extracted with ethyl acetate, dried over anhydrous sodium sulfate, and distilled under reduced pressure to give 1,4-Di(2,2,2-trifluoroethoxy)benzene in approximately 85% yield.

1,4-Di(2,2,2-trifluoroethoxy)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-Di(2,2,2-trifluoroethoxy)benzene Suppliers

Global Suppliers ( 106)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 18918157536; sales8178@energy-chemical.com China 45000 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Adamas Reagent, Ltd. 4006009262 13023226327 hmj@titansci.com China 14098 59
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Yolne Chemical Co., Ltd. 021-62960152 934678158@qq.com China 9886 55
Shanghai Meishui Chemical Technology Co., Ltd 021-60549325 18616193163 China 4518 56
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Adamas Reagent, Ltd. 59
T&W GROUP 58
Shanghai T&W Pharmaceutical Co., Ltd. 58
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Yolne Chemical Co., Ltd. 55
Shanghai Meishui Chemical Technology Co., Ltd 56

View Latest Price from 1,4-Di(2,2,2-trifluoroethoxy)benzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,4-Di(2,2,2-trifluoroethoxy)benzene pictures 2026-09-02 1,4-Di(2,2,2-trifluoroethoxy)benzene
66300-61-6
 $1.00-101.00 1KG 99% Henan Fengda Chemical Co., Ltd
1,4-Di(2,2,2-trifluoroethoxy)benzene pictures 2021-08-12 1,4-Di(2,2,2-trifluoroethoxy)benzene
66300-61-6
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1,4-Di(2,2,2-trifluoroethoxy)benzene pictures 2019-07-06 1,4-Di(2,2,2-trifluoroethoxy)benzene
66300-61-6
$500.00 1KG 99% 100kg Career Henan Chemical Co

66300-61-6 (1,4-Di(2,2,2-trifluoroethoxy)benzene) Related Search:

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1,4-Bis(2,2,2-trifluoroethoxy)benzene 97% 1,4-Bis(2,2,2-trifluoroethoxy)benzene97% 1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE 1,4-Bis(2,2,2-Trifluoroethoxy)-Benzene （For Flecaintde） Flecainide Impurity 17 Benzene, 1,4-bis(2,2,2-trifluoroethoxy)- 1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE 66300-61-6 Flecainide Impurity 3 1,4-BIS(2,2,2-TRIFLUOROETHOXY)BENZENE 66300-61-6 C10H8F6O2