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BCI-137 (BCI137)

BCI-137 (BCI137) structure

CAS No.: 112170-24-8

Chemical Name:: BCI-137 (BCI137)

Synonyms: BCI-137 (BCI137);BCI-137, 10 mM in DMSO;Argonaute-2 Inhibitor, BCI-137;((2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl)alanine;Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]-;2-(2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid

CBNumber:: CB04844532

Molecular Formula:: C11H11N3O6S

Molecular Weight:: 313.29

MDL Number:: MFCD05148320

MOL File:: 112170-24-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:24

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BCI-137 (BCI137) Properties

Density	1.566±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 100mg/mL
form	Solid
pka	3.30±0.10(Predicted)
color	White to off-white
SMILES	CC(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)NC(=O)C(=O)N2
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

BCI-137 (BCI137) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	5.31552	Argonaute-2 Inhibitor, BCI-137	112170-24-8	25 mg	$292	2026-04-30	Buy
Biosynth	MEA17024	2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid	112170-24-8	50mg	$668	2026-06-04	Buy
Biosynth	MEA17024	2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid	112170-24-8	0.5g	$2100.4	2026-06-04	Buy
ChemScene	CS-0066441	BCI-137 ≥98%	112170-24-8	1g	$1522	2026-06-04	Buy
aablocks	AA01BFRI	2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid 98%	112170-24-8	5mg	$64	2026-05-29	Buy

Product number	Packaging	Price	Buy
5.31552	25 mg	$292	Buy
MEA17024	50mg	$668	Buy
MEA17024	0.5g	$2100.4	Buy
CS-0066441	1g	$1522	Buy
AA01BFRI	5mg	$64	Buy

BCI-137 (BCI137) Chemical Properties, Uses, Production

Description

BCI-137 is an Argonaute 2 (Ago2) ligand that acts by targeting the MicroRNA Binding Domain.

Uses

BCI-137 is a competitive AGO2 inhibitor, with an IC50 of 342 μM. BCI-137 tightly binds to several residues of the Mid domain[1].

References

[1] Poser E, et, al. Surface Plasmon Resonance: A Useful Strategy for the Identification of Small Molecule Argonaute 2 Protein Binders. Methods Mol Biol. 2017;1517:223-237. DOI:10.1007/978-1-4939-6563-2_16

BCI-137 (BCI137) Preparation Products And Raw materials

Raw materials

Preparation Products

BCI-137 (BCI137) Suppliers

Global Suppliers ( 13)

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Hopschain Chemical Co.,Ltd.	85528066 13775048983	sales@hopschem.com	China	31548	55
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	54996	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736	2853117764@yongstandards.com	China	9999	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58

Supplier	Advantage
Changzhou Hopschain Chemical Co.,Ltd.	55
BOC Sciences	58
TargetMol Chemicals Inc.	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
Hubei Xinyang Medical Technology Co., Ltd	58
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

112170-24-8 (BCI-137 (BCI137)) Related Search:

2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride 1,2,3,4-tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid (2,3-Dioxo-1,2,3,4-tetrahydro-quinoxaline-6-sulfonylamino)-acetic acid N,N-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide 2,3-Dihydroxy-quinoxaline-6-sulfonic acid amide

6-Quinoxalinesulfonamide, 1-ethyl-1,2,3,4-tetrahydro-N,N-dimethyl-2,3-dioxo-

1of2

BCI-137 (BCI137) 2-(2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]- ((2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)sulfonyl)alanine BCI-137, 10 mM in DMSO Argonaute-2 Inhibitor, BCI-137 112170-24-8