BRD2492 (BRD 2492)
- CAS No.
- 1821669-43-5
- Chemical Name:
- BRD2492 (BRD 2492)
- Synonyms
- BRD2492;BRD2492 (BRD 2492);4-Acetamido-N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide;Benzamide, 4-(acetylamino)-N-[2-amino-5-(4-pyridinyl)phenyl]-
- CBNumber:
- CB04844592
- Molecular Formula:
- C20H18N4O2
- Molecular Weight:
- 346.38
- MDL Number:
- MOL File:
- 1821669-43-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
BRD2492 (BRD 2492) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0084059 | BRD2492 99.18% | 1821669-43-5 | 5mg | $141 | 2026-06-04 | Buy |
| ChemScene | CS-0084059 | BRD2492 99.18% | 1821669-43-5 | 10mg | $211 | 2026-06-04 | Buy |
| ApexBio Technology | BA4159 | BRD2492 | 1821669-43-5 | 5mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA4159 | BRD2492 | 1821669-43-5 | 10mg | $122 | 2026-05-06 | Buy |
| aablocks | AA027LII | 4-Acetamido-N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide 98 | 1821669-43-5 | 1mg | $44 | 2026-06-02 | Buy |
BRD2492 (BRD 2492) Chemical Properties, Uses, Production
Description
BRD2492 is a novel potent HDAC1/2 inhibitor.
Uses
BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01μM and 11.13μM for T-47D and MCF-7 cells, respectively[1].
IC 50
HDAC1: 13.2 nM (IC50); HDAC2: 77.2 nM (IC50); HDAC3: 8908 nM (IC50); HDAC6: >1000 nM (IC50)
References
[1] Linda Schker-Hübner, et al. Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors. ChemMedChem. 2022 May 4;17(9):e202100755. DOI:10.1002/cmdc.202100755
BRD2492 (BRD 2492) Preparation Products And Raw materials
Raw materials
Preparation Products
BRD2492 (BRD 2492) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2996 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Aikon International Limited | 17714375163 | hywu@aikonchem.com | China | 9974 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |






