3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo-
- CAS No.
- 883564-93-0
- Chemical Name:
- 3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo-
- Synonyms
- 13,13-dimethyl-11-oxo-3,6,9,12-tetraoxatetradecanoic acid;2-[2-[2-(2-tert-butoxy-2-oxo-ethoxy)ethoxy]ethoxy]acetic acid;HOOCCH2O-PEG2-CH2COOtBu;3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo-;13,13-Dimethyl-11-oxo-3,6,9,12-tetraoxatetradecan-1-oic acid;2-[2-[2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]ethoxy]ethoxy]acetic acid;HOOCCH2O-PEG2-CH2COOtBu/3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo-
- CBNumber:
- CB04847407
- Molecular Formula:
- C12H22O7
- Molecular Weight:
- 278.3
- MDL Number:
- MOL File:
- 883564-93-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| t-Butyl acetate-PEG2-CH2COOH ≥97% | CS-0147724 | 250mg | $54 |
| t-Butyl acetate-PEG2-CH2COOH ≥97% | CS-0147724 | 1g | $136 |
| t-Butyl acetate-PEG2-CH2COOH ≥97% | CS-0147724 | 5g | $494 |
| t-butyl acetate-PEG2-CH2COOH | bp-28395 | 500MG | $110 |
| t-butyl acetate-PEG2-CH2COOH | bp-28395 | 1G | $210 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0147724 | t-Butyl acetate-PEG2-CH2COOH ≥97% | 883564-93-0 | 250mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0147724 | t-Butyl acetate-PEG2-CH2COOH ≥97% | 883564-93-0 | 1g | $136 | 2026-06-04 | Buy |
| ChemScene | CS-0147724 | t-Butyl acetate-PEG2-CH2COOH ≥97% | 883564-93-0 | 5g | $494 | 2026-06-04 | Buy |
| BroadPharm | bp-28395 | t-butyl acetate-PEG2-CH2COOH | 883564-93-0 | 500MG | $110 | 2026-05-24 | Buy |
| BroadPharm | bp-28395 | t-butyl acetate-PEG2-CH2COOH | 883564-93-0 | 1G | $210 | 2026-05-24 | Buy |
3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo- Chemical Properties,Uses,Production
Description
t-butyl acetate-PEG2-CH2COOH is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo- Preparation Products And Raw materials
Raw materials
Preparation Products
3,6,9,12-Tetraoxatetradecanoic acid, 13,13-dimethyl-11-oxo- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Nanjing Junnahe Biopharmaceutical Co., Ltd | 025-58367986 17351780683 | amy.xiang@ally-chem.com | China | 354 | 60 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4882 | 55 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4538 | 58 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 3905209149@qq.com | China | 9722 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
