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ChemicalBook >> CAS DataBase List >>rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Structure
rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine structure
CAS No.
87304-15-2
Chemical Name:
rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine
Synonyms
rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine;L-Leucine, N-[(2S,3R)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]-;(2S)-2-[(2S,3R)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
CBNumber:
CB04888976
Molecular Formula:
C21H32N2O6
Molecular Weight:
408.49
MDL Number:
MFCD31631159
MOL File:
87304-15-2.mol
MSDS File:
SDS
Last updated:2026-07-27 08:51:18
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rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Properties

Melting point 124-125 °C
Boiling point 660.113±55.00 °C(Press: 760.00 Torr)(predicted)
Density 1.171±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 3.377±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0100090 E3 ligase Ligand 9 ≥98% 87304-15-2 100mg $203 2026-06-04 Buy
ChemScene CS-0100090 E3 ligase Ligand 9 ≥98% 87304-15-2 250mg $280 2026-06-04 Buy
ChemScene CS-0100090 E3 ligase Ligand 9 ≥98% 87304-15-2 1g $756 2026-06-04 Buy
aablocks AA01KDQL E3 Ligase Ligand 9 95% 87304-15-2 25mg $124 2026-05-30 Buy
aablocks AA01KDQL E3 Ligase Ligand 9 95% 87304-15-2 100mg $248 2026-05-30 Buy
Product number Packaging Price Buy
CS-0100090 100mg $203 Buy
CS-0100090 250mg $280 Buy
CS-0100090 1g $756 Buy
AA01KDQL 25mg $124 Buy
AA01KDQL 100mg $248 Buy

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Chemical Properties,Uses,Production

Description

E3 Ligase ligand 9 targets ubiquitin-protein ligases in order to activate the E3 ubiquitin ligase. It can then treat metabolic disorders and psychiatric disorders.

Uses

E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

References

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Preparation Products And Raw materials

Raw materials

Preparation Products

rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
AF Biochem Co., Ltd. +86-028-60911900 13540204019 sales@afbiochem.com China 479 57
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58
Guangzhou Zhiya Chemdrugs Co.,Ltd 18122150900 sculk28@163.com China 645 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Shanghai ruichang pharmaceutical technology co., LTD 18621054990 maychemicals@sina.com China 673 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
Blocksynth Pharmaceutical Technology Co.,Ltd 0086-19817745290; 19817745290 bd@blocksynth.com China 5971 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
AF Biochem Co., Ltd. 57
Shanghai Topbiochem Technology Co., Ltd 58
Guangzhou Zhiya Chemdrugs Co.,Ltd 55
Shanghai Chaolan Chemical Technology Center 58
SuZhou Medinoah Co.,LTD. 58
Shanghai ruichang pharmaceutical technology co., LTD 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Blocksynth Pharmaceutical Technology Co.,Ltd 58
TargetMol Chemicals Inc. 58

View Lastest Price from rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
E3 ligase Ligand 9 pictures 2026-04-20 E3 ligase Ligand 9
87304-15-2
 10g TargetMol Chemicals Inc.

87304-15-2(rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine)Related Search:

Boc-Phe-Leu-OH rac-((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine E3 ligase Ligand 13 Boc-(2R,3S)-AHPA N-Boc-(2R,3R)-2-hydroxy-3-amino-4-phenylbutanoic acid
N-Boc-(2R,3R)-2-hydroxy-3-amino-4-phenylbutanoic acid

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rac-((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine L-Leucine, N-[(2S,3R)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]- (2S)-2-[(2S,3R)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid 87304-15-2