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E3 ligase Ligand 13

E3 ligase Ligand 13 structure

CAS No.: 2701565-75-3

Chemical Name:: E3 ligase Ligand 13

Synonyms: E3 ligase Ligand 13;D-Leucine, N-[(2R,3S)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]-

CBNumber:: CB014255478

Molecular Formula:: C31H34N2O6

Molecular Weight:: 530.61

MDL Number:

MOL File:: 2701565-75-3.mol

Last updated:2025-04-18 09:51:24

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E3 ligase Ligand 13 Properties

Boiling point	815.760±65.00 °C(Press: 760.00 Torr)(predicted)
Density	1.253±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	3.369±0.10(predicted)

E3 ligase Ligand 13 Chemical Properties,Uses,Production

Uses

E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

IC 50

IAP

References

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

E3 ligase Ligand 13 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand 13 Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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E3 ligase Ligand 13 D-Leucine, N-[(2R,3S)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]- 2701565-75-3