ChemicalBook >> CAS DataBase List >>BI-6C9

BI-6C9

CAS No.
791835-21-7
Chemical Name:
BI-6C9
Synonyms
BI-6C9, 10 mM in DMSO;N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9
CBNumber:
CB0496964
Molecular Formula:
C23H25N3O4S2
Molecular Weight:
471.59
MDL Number:
MFCD07784498
MOL File:
791835-21-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18

BI-6C9 Properties

Density 1.36±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility DMSO: 24 mg/mL, soluble
form solid
pka 11.58±0.50(Predicted)
color off-white
InChI 1S/C23H25N3O4S2/c1-30-19-8-14-22(15-9-19)32(28,29)25-16-2-3-23(27)26-18-6-12-21(13-7-18)31-20-10-4-17(24)5-11-20/h4-15,25H,2-3,16,24H2,1H3,(H,26,27)
InChIKey LCFUJBSKPDPGKO-UHFFFAOYSA-N
SMILES COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc2ccc(Sc3ccc(N)cc3)cc2
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
Storage Class 11 - Combustible Solids

BI-6C9 price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B0186 BI-6C9 ≥97% (HPLC), solid 791835-21-7 1mg $87.5 2026-04-30 Buy
Sigma-Aldrich B0186 BI-6C9 ≥97% (HPLC), solid 791835-21-7 5mg $303 2026-04-30 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 791835-21-7 1mg $62 2026-04-30 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 791835-21-7 5mg $266 2026-04-30 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 791835-21-7 10mg $472 2026-04-30 Buy
Product number Packaging Price Buy
B0186 1mg $87.5 Buy
B0186 5mg $303 Buy
17265 1mg $62 Buy
17265 5mg $266 Buy
17265 10mg $472 Buy

BI-6C9 Chemical Properties,Uses,Production

Uses

BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.

Biological Activity

BI-6C9 is a tBid inhibitor and antiapoptotic.

BI-6C9 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9796 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-13601744364 13601744364 chemsharker@126.com China 1159 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58

View Lastest Price from BI-6C9 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BI-6C9 pictures 2026-07-14 BI-6C9
791835-21-7
$60.00-222.00 98.39% 10g TargetMol Chemicals Inc.
  • BI-6C9 pictures
  • BI-6C9
    791835-21-7
  • $60.00-222.00
  • 98.39%
  • TargetMol Chemicals Inc.

BI-6C9 Spectrum

N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]- N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9 BI-6C9, 10 mM in DMSO 791835-21-7