Esomeprazole hemistrontium
- CAS No.
- 914613-86-8
- Chemical Name:
- Esomeprazole hemistrontium
- Synonyms
- Esomeprazole hemistrontium
- CBNumber:
- CB05493322
- Molecular Formula:
- C17H21N3O3SSr
- Molecular Weight:
- 435.05
- MDL Number:
- MOL File:
- 914613-86-8.mol
- MSDS File:
- SDS
| FDA UNII | SCC2RK476A |
|---|
Esomeprazole hemistrontium Chemical Properties, Uses, Production
Uses
Esomeprazole ((S)-Omeprazole) hemistrontium is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole hemistrontium has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].
in vivo
Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) hemistrontium treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].
| Animal Model: | C57BL/6J mice (8-weeks old, 25-30 g) treated with cotton smoke-induced lung injury[2] |
| Dosage: | 30 mg/kg, 300 mg/kg |
| Administration: | Oral gavage; daily; for 19 or 11 days |
| Result: | Significantly inhibited the progression of fibrosis throughout the lungs of the animals. |
References
[1] Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46. DOI:10.18433/j34608
[2] Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16. DOI:10.3389/fphar.2017.00016
[3] Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. DOI:10.1093/ajhp/59.14.1333
Esomeprazole hemistrontium Preparation Products And Raw materials
Raw materials
Preparation Products
Esomeprazole hemistrontium Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from Esomeprazole hemistrontium manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Esomeprazole hemistrontium
914613-86-8
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Esomeprazole hemistrontium
914613-86-8
- $1520.00-2500.00
- TargetMol Chemicals Inc.
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