1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester
- CAS No.
- 1346153-07-8
- Chemical Name:
- 1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester
- Synonyms
- Boc-Pip-butyn;4-(3-Butyn-1-yl)-1-Boc-piperidine;tert-butyl 4-(but-3-ynyl)piperidine-1-carboxylate;tert-Butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate;tert-butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate - [AC80617];1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB06135780
- Molecular Formula:
- C14H23NO2
- Molecular Weight:
- 237.34
- MDL Number:
- MOL File:
- 1346153-07-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501 |
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Strem Chemicals | 06-0194 | tert-Butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate, 95% 95% | 1346153-07-8 | 500mg | $600 | 2026-04-30 | Buy |
| Strem Chemicals | 06-0194 | tert-Butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate, 95% 95% | 1346153-07-8 | 1g | $825 | 2026-04-30 | Buy |
| Strem Chemicals | 06-0194 | tert-Butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate, 95% 95% | 1346153-07-8 | 2.5g | $1450 | 2026-04-30 | Buy |
| ChemScene | CS-0527484 | Boc-Pip-butyn ≥95% | 1346153-07-8 | 100mg | $58 | 2026-06-04 | Buy |
| ChemScene | CS-0527484 | Boc-Pip-butyn ≥95% | 1346153-07-8 | 250mg | $98 | 2026-06-04 | Buy |
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Chemical Properties, Uses, Production
Uses
Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Biological Activity
Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1].
IC 50
Alkyl/ether
References
[1]. Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202110864.
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Tube Pharmaceutical Co., Ltd. | 021-54338626 18017892860 | sales@tubepharm.com | China | 2709 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| Shaoyuan Technology (Shanghai) Co., Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 9831 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5568 | 58 |
| Shaanxi Gulliver Biotechnology Research Co., Ltd | 13892423764 | 3961484990@qq.com | China | 3093 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
