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Phenylpyropene A

CAS No.
189564-20-3
Chemical Name:
Phenylpyropene A
Synonyms
Phenylpyropene A;(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-11-one;2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-
CBNumber:
CB06197858
Molecular Formula:
C32H38O10
Molecular Weight:
582.64
MDL Number:
MOL File:
189564-20-3.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

Phenylpyropene A Properties

Boiling point 676.9±55.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Residue
pka 11.78±0.70(Predicted)

Phenylpyropene A price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29594 Phenylpyropene A ≥95% 189564-20-3 1mg $215 2026-04-30 Buy
Cayman Chemical 29594 Phenylpyropene A ≥95% 189564-20-3 5mg $966 2026-04-30 Buy
Biosynth PHA56420 Phenylpyropene A 189564-20-3 5mg $1413.25 2026-06-04 Buy
Biosynth PHA56420 Phenylpyropene A 189564-20-3 10mg $2261.1 2026-06-04 Buy
Biosynth PHA56420 Phenylpyropene A 189564-20-3 25mg $4239.75 2026-06-04 Buy
Product number Packaging Price Buy
29594 1mg $215 Buy
29594 5mg $966 Buy
PHA56420 5mg $1413.25 Buy
PHA56420 10mg $2261.1 Buy
PHA56420 25mg $4239.75 Buy

Phenylpyropene A Chemical Properties,Uses,Production

Description

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3

Uses

Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 0.8 μM[1].

References

1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Penicillium griseofulvum F1959 J. Antibiot. (Tokyo) 55(11),1004-1008(2002).
2. Lee, S.W., Rho, M.C., Choi, J.H., et al. Inhibition of diacylglycerol acyltransferase by phenylpyropenes produced by Penicillium griseofulvum F1959 J. Microbiol. Biotechnol. 18(11),1785-1788(2008).
3. Horikoshi, R., Goto, K., Mitomi, M., et al. Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening J. Antibiot. (Tokyo) 70(3),272-276(2017).

Phenylpyropene A Preparation Products And Raw materials

Raw materials

Preparation Products

Phenylpyropene A Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 13120558703 sales@scrbio.com China 9873 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Shanghai Weiyite Biotechnology Co., Ltd 15317051735 zhaojing@wytsci.com China 10000 58
Wuhan SynBioLily Biotechnology Co.,Ltd. 18971458902 yangsong@synbiolily.com China 482 58
Phenylpyropene A 2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)- (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3,6-bis(acetyloxy)-4-[(acetyloxy)methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-9-phenyl-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-11-one 189564-20-3