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4-Hydroxy-L-phenylglycine

CAS No.
32462-30-9
Chemical Name:
4-Hydroxy-L-phenylglycine
Synonyms
(S)-2-AMino-2-(4-hydroxyphenyl)acetic acid;OXFENICINE;L-NORTYR;(2S)-amino(4-hydroxyphenyl)acetic acid;(2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid;H-HPG-OH;UK-25842;L-(+)-Hydroxy;L-4-OH-Phg-OH;-(+)-2-phenyL
CBNumber:
CB1765553
Molecular Formula:
C8H9NO3
Molecular Weight:
167.16
MDL Number:
MFCD00065932
MOL File:
32462-30-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:45:59

4-Hydroxy-L-phenylglycine Properties

Melting point ~240 °C (dec.)
alpha 158 º (c=1% in 1M HCl)
Boiling point 365.8±32.0 °C(Predicted)
Density 1.396±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aquous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Water (Slightly)
pka 2.15±0.10(Predicted)
form Solid
color White to Off-White
optical activity [α]20/D +158±3°, c = 1% in 1 M HCl
BRN 3589845
Major Application peptide synthesis
InChI InChI=1/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s3
InChIKey LJCWONGJFPCTTL-ZETCQYMHSA-N
SMILES [C@@H](C1C=CC(O)=CC=1)(N)C(=O)O |&1:0,r|
CAS DataBase Reference 32462-30-9(CAS DataBase Reference)
FDA UNII 9YH0WH2Z02
EPA Substance Registry System Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.S)- (32462-30-9)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  TSCA listed
HS Code  2922.50.4000
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-Hydroxy-L-phenylglycine price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 56160 4-Hydroxy-L-phenylglycine ≥99.0% (NT) 32462-30-9 10g $140 2026-04-30 Buy
Sigma-Aldrich 56160 4-Hydroxy-L-phenylglycine ≥99.0% (NT) 32462-30-9 50g $536 2026-04-30 Buy
TCI Chemical H1389 4-Hydroxy-L-(+)-2-phenylglycine >99.0%(HPLC)(T) 32462-30-9 5g $98 2026-04-30 Buy
TCI Chemical H1389 4-Hydroxy-L-(+)-2-phenylglycine >99.0%(HPLC)(T) 32462-30-9 25g $295 2026-04-30 Buy
Cayman Chemical 33698 Oxfenicine ≥95% 32462-30-9 1g $41 2026-04-30 Buy
Product number Packaging Price Buy
56160 10g $140 Buy
56160 50g $536 Buy
H1389 5g $98 Buy
H1389 25g $295 Buy
33698 1g $41 Buy

4-Hydroxy-L-phenylglycine Chemical Properties, Uses, Production

Chemical Properties

White crystalline

Uses

Vasodilator.

Uses

4-Hydroxy-L-(+)-2-phenylglycine is a carnitine palmitoyltransferase-1 inhibitor. 4-Hydroxy-L-(+)-2-phenylglycine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance.

Definition

ChEBI: The L-enantiomer of 4-hydroxyphenylglycine.

reaction suitability

reaction type: solution phase peptide synthesis

in vivo

Oxfenicine (150 mg/kg, i.p., once daily for 3 weeks) treatment significantly reduces adiposity in high-fat diet rats[4].

Animal Model:Male Sprague-Dawley rats fed a high-fat (HF) diet[4]
Dosage:150 mg/kg
Administration:intraperitoneal injection (i.p.) once daily for 3 weeks
Result:Reduced whole-body fat oxidation, body weight, adiposity, and improved insulin sensitivity in HF-fed rats.

4-Hydroxy-L-phenylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 280)
Supplier Tel Email Country ProdList Advantage
Shanghai Chiral Chemicals Inc. 021-37285021 13472570865 tym7xi@aliyun.com China 299 64
Shanghai Chang-Gen Chemical Technology Co., Ltd. 021-69106814 13917161715 3007500651@qq.com China 80 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57

View Latest Price from 4-Hydroxy-L-phenylglycine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Oxfenicine pictures 2026-08-22 Oxfenicine
32462-30-9
$40.00 99.60% 10g TargetMol Chemicals Inc.
4-Hydroxy-L-phenylglycine pictures 2019-07-06 4-Hydroxy-L-phenylglycine
32462-30-9
$1.00 1kg 95%-99% Career Henan Chemical Co
  • Oxfenicine pictures
  • Oxfenicine
    32462-30-9
  • $40.00
  • 99.60%
  • TargetMol Chemicals Inc.
H-PHG(4-HYDROXY)-OH H-HPG-OH L-(+)-A-4-HYDROXYPHENYLGLYCINE L-4-HYDROXYPHENYLGLYCINE L-(+)-P-HYDROXYPHENYLGLYCINE L-NORTYR 4-HYDROXY-L-PHENYLGLYCINE (S)-AMINO-(4-HYDROXY-PHENYL)-ACETIC ACID L(+)4-Phydroxyphenylglycine L-(+)-Hydroxy L-(+)-alpha-4-hydroxyphenylglycine L-4-OH-Phg-OH 4-HYDROXY-L-PHENYLGLYCINE 99+% L-P-HYDROXYPHENYGLYCINE (S)-2-(4-Hydroxyphenyl)glycine (S)-α-Amino-4-hydroxybenzeneacetic acid UK-25842 4-Hydroxy-L-(+)-2-phenylglycine 4-Hydroxy-L-phenylglycine >=99.0% (NT) 4-Hydroxy-L-(+)-2-phenylglycine Benzeneacetic acid, a-amino-4-hydroxy-, (aS)- 4-Hydroxy-L-(+)-2-phenylglycine> Benzeneacetic acid, α-amino-4-hydroxy-, (αS)- -(+)-2-phenyL (2S)-2-amino-2-(4-hydroxyphenyl)aceticaci L-(+)-2-(4-Hydroxyphenyl)glycine 4-Hydroxy-L-phenylglycine USP/EP/BP (L)-(+)-α-4-hydroxyphenyl glycine 4-Hydroxy-L-phenylglycine,97% 4-Hydroxy-L< 4-Hydroxy-L-phenylglycine (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid - [A86489] (2S)-amino(4-hydroxyphenyl)acetic acid (2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid (S)-2-AMino-2-(4-hydroxyphenyl)acetic acid OXFENICINE 32462-30-9 Peptide Synthesis Phenylglycine Derivatives Specialty Synthesis Unnatural Amino Acid Derivatives Amino ACIDS SERIES