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2-AMINO-6-CHLORO-PHENOL

2-AMINO-6-CHLORO-PHENOL Structure
2-AMINO-6-CHLORO-PHENOL structure
CAS No.
38191-33-2
Chemical Name:
2-AMINO-6-CHLORO-PHENOL
Synonyms
2-AMino-6-chlorphenol;2-AMINO-6-CHLORO-PHENOL;2-chloro-6-aMinophenole;3-Chloro-2-hydroxyaniline;phenol, 2-amino-6-chloro-
CBNumber:
CB0655640
Molecular Formula:
C6H6ClNO
Molecular Weight:
143.57
MDL Number:
MFCD07801210
MOL File:
38191-33-2.mol
MSDS File:
SDS
Last updated:2025-08-16 20:45:37
Product description Number Pack Size Price
2-Amino-6-chlorophenol TMT00393 1 g $550
2-Amino-6-chlorophenol A576675 500mg $40
2-Amino-6-chlorophenol A576675 5g $300
2-Amino-6-chlorophenol 4656-5-92 5G $240
2-Amino-6-chlorophenol FA120252 5G $300
More product size
Request For Quotation

2-AMINO-6-CHLORO-PHENOL Properties

Melting point 80-81℃
Boiling point 247℃
Density 1.406
Flash point 103℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form solid
pka 8.28±0.10(Predicted)
color Grey
InChI InChI=1S/C6H6ClNO/c7-4-2-1-3-5(8)6(4)9/h1-3,9H,8H2
InChIKey QUIIUKFPLUUSGQ-UHFFFAOYSA-N
SMILES C1(O)=C(Cl)C=CC=C1N
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P312-P260-P280
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2922290090

2-AMINO-6-CHLORO-PHENOL price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich TMT00393 2-Amino-6-chlorophenol 1 g $550 2025-07-31 Buy
TRC A576675 2-Amino-6-chlorophenol 38191-33-2 500mg $40 2021-12-16 Buy
TRC A576675 2-Amino-6-chlorophenol 38191-33-2 5g $300 2021-12-16 Buy
SynQuest Laboratories 4656-5-92 2-Amino-6-chlorophenol 38191-33-2 5G $240 2021-12-16 Buy
Biosynth Carbosynth FA120252 2-Amino-6-chlorophenol 38191-33-2 5G $300 2021-12-16 Buy
Product number Packaging Price Buy
TMT00393 1 g $550 Buy
A576675 500mg $40 Buy
A576675 5g $300 Buy
4656-5-92 5G $240 Buy
FA120252 5G $300 Buy

2-AMINO-6-CHLORO-PHENOL Chemical Properties,Uses,Production

Uses

2-Amino-6-Chlorophenol is used to synthesize HT2C receptor agonists with high selectivity in functional and binding assays.

Synthesis

2-Chloro-6-nitrophenol

603-86-1

2-AMINO-6-CHLORO-PHENOL

38191-33-2

General procedure for the synthesis of 2-amino-6-chlorophenol from 2-chloro-6-nitrophenol: 2-chloro-6-nitrophenol (1.05 g, 6.03 mmol) was mixed with tin powder (2.32 g, 19.5 mmol) in glacial acetic acid, and the reaction was stirred for 18 hours at 80 °C. After completion of the reaction, the reaction mixture was diluted with deionized water (120 mL) and filtered to remove insoluble material. The filtrate was extracted with ethyl acetate (1 x 100 mL, followed by 2 x 50 mL). The organic phases were combined, washed with saturated saline (3 × 50 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification by rapid column chromatography on silica gel (eluent ratio 2:1 hexane:ethyl acetate) afforded 2-amino-6-chlorophenol as a brown to white crystalline solid (476 mg, 55% yield).1H-NMR (500 MHz, CDCl3) δ 6.73 (dd, J = 1.7, 8.1 Hz, 1H), 6.69 (t, J = 7.8 Hz, 1H ), 6.62 (dd, J = 1.7, 7.7 Hz, 1H), 5.46 (br s, 1H), 3.84 (br s, 2H); 13C-NMR (125 MHz, CDCl3) δ 139.32, 135.73, 121.28, 119.87, 118.31, 114.42; ESI-MS m/z 144 [M +H]+, calculated value of 144 for the molecular formula C6H7ClNO.

References

[1] Liebigs Annalen der Chemie, 1994, # 3, p. 269 - 276
[2] Journal of the Iranian Chemical Society, 2018, vol. 15, # 2, p. 281 - 291
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 23, p. 7974 - 7985
[4] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 15, p. 3521 - 3525
[5] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 15, p. 3441 - 3449

2-AMINO-6-CHLORO-PHENOL Preparation Products And Raw materials

Raw materials

2-Chloro-6-nitrophenol Iron

Preparation Products

2-AMINO-6-CHLORO-PHENOL Suppliers

Global( 100)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8757 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29796 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569262 +86-15003564040 1061@dideu.com China 3983 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14358 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Win-Win chemical CO., Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from 2-AMINO-6-CHLORO-PHENOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-6-CHLORO-PHENOL pictures 2026-01-05 2-AMINO-6-CHLORO-PHENOL
38191-33-2
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-AMINO-6-CHLORO-PHENOL pictures 2026-01-05 2-AMINO-6-CHLORO-PHENOL
38191-33-2
 US $0.00-0.00 / KG 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2-Amino-6-chlorophenol pictures 2025-10-13 2-Amino-6-chlorophenol
38191-33-2
 US $1.10-9.90 / kg 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-AMINO-6-CHLORO-PHENOL Spectrum

2-AMINO-6-CHLORO-PHENOL(38191-33-2)1HNMR

38191-33-2(2-AMINO-6-CHLORO-PHENOL)Related Search:

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phenol, 2-amino-6-chloro- 2-chloro-6-aMinophenole 3-Chloro-2-hydroxyaniline 2-AMino-6-chlorphenol 2-AMINO-6-CHLORO-PHENOL 38191-33-2