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Ethyl propionylacetate

Ethyl propionylacetate structure

CAS No.: 4949-44-4

Chemical Name:: Ethyl propionylacetate

Synonyms: ETHYL 3-OXOPENTANOATE;NSC 7251;NSC 78662;ETHYL 3-OXOVALERATE;Ethyl Propioacetate;thyl 3-ketopentanoate;Ethyl3-Oxovalerate>ETHYL PROPIONYLACETATE;Ethyl 3-oxo-n-valerate;Ethyl propanoylacetate

CBNumber:: CB0672337

Molecular Formula:: C7H12O3

Molecular Weight:: 144.17

MDL Number:: MFCD00009317

MOL File:: 4949-44-4.mol

MSDS File:: SDS

Last updated:2025-08-26 13:29:58

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Ethyl propionylacetate Properties

Melting point	98 °C
Boiling point	83-84 °C/12 mmHg (lit.)
Density	1.012 g/mL at 25 °C (lit.)
refractive index	n20/D 1.422(lit.)
Flash point	172 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Miscible with glacial acetic acid.
form	Liquid
pka	10.58±0.46(Predicted)
color	Clear colorless to pale yellow
Specific Gravity	1.01
BRN	970270
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey	UDRCONFHWYGWFI-UHFFFAOYSA-N
CAS DataBase Reference	4949-44-4(CAS DataBase Reference)
FDA UNII	P45XZ5RD8B
NIST Chemistry Reference	Ethyl propionylacetate(4949-44-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H227-H315-H319

Precautionary statements

P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501-P210e-P261-P280a-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

TSCA

HazardClass

IRRITANT

HS Code

29183000

NFPA 704

	2
2		0

Ethyl propionylacetate price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	247162	Ethyl propionylacetate 97%	4949-44-4	5g	$87.5	2025-07-31	Buy
TCI Chemical	K0031	Ethyl 3-Oxovalerate >97.0%(GC)	4949-44-4	5g	$31	2025-07-31	Buy
TCI Chemical	K0031	Ethyl 3-Oxovalerate >97.0%(GC)	4949-44-4	25g	$114	2025-07-31	Buy
TRC	E925395	Ethyl propionylacetate	4949-44-4	1g	$110	2021-12-16	Buy
Chem-Impex	22466	Ethyl3-oxovalerate,97%(GC) 97%(GC)	4949-44-4	5G	$25.76	2021-12-16	Buy

Product number	Packaging	Price	Buy
247162	5g	$87.5	Buy
K0031	5g	$31	Buy
K0031	25g	$114	Buy
E925395	1g	$110	Buy
22466	5G	$25.76	Buy

Ethyl propionylacetate Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

An intermediate of Rosuvastatin.

Uses

Ethyl propionylacetate acts as a precursor used in the preparation of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring. Further, it is used to prepare 3-propionyl-2H-cyclohepta[b]furan-2-one.

Uses

Ethyl propionylacetate has been used in the synthesis of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring.

Synthesis Reference(s)

Synthesis, p. 829, 1978 DOI: 10.1055/s-1978-24903

General Description

Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one.

Ethyl propionylacetate synthesis

Synthesis of Ethyl propionylacetate from 2,2-Dimethyl-1,3-dioxane-4,6-dione and Propionyl chloride

Ethyl propionylacetate Preparation Products And Raw materials

Raw materials

TRIPHENYLMETHYL SODIUM 2,2-diMethyl-5-propanoyl-1,3-dioxane-4,6-dione Pentanoic acid, 2-diazo-3-hydroxy-, ethyl ester 2-Oxazolidinone, 3-(1-oxopropyl)- Carbon tetrachloride

Iodomethane Ethyl acetate 3-Propionylthiazolidine-2-thione Propionyl chloride Pentanoic acid,3-hydroxy-, ethyl ester

3,5-Dimethyl-1-(1-Oxopropyl)-1H-Pyrazole 4-Pentenoic acid, 3-hydroxy-, ethyl ester 2,2-Dimethyl-1,3-dioxane-4,6-dione Diethyl malonate

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Preparation Products

Etodolac ETHYL 4-FLUORO-3-OXOPENTANOATE

Ethyl propionylacetate Suppliers

Global( 322)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12371	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	8979	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Ethyl propionylacetate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-15	Ethyl propionylacetate 4949-44-4	US $0.00 / Kg/Drum	1KG	98%min	500KGS	WUHAN FORTUNA CHEMICAL CO., LTD
2025-08-26	Ethyl propionylacetate 4949-44-4	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-07-25	Ethyl propionylacetate 4949-44-4	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

Ethyl propionylacetate
4949-44-4
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Ethyl propionylacetate
4949-44-4
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

Ethyl propionylacetate
4949-44-4
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

Ethyl propionylacetate Spectrum

Ethyl propionylacetate(4949-44-4)MS Ethyl propionylacetate(4949-44-4)¹HNMR Ethyl propionylacetate(4949-44-4)¹³CNMR Ethyl propionylacetate(4949-44-4)IR1 Ethyl propionylacetate(4949-44-4)Raman

4949-44-4(Ethyl propionylacetate)Related Search:

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Methyl 3-oxovalerate Pitavastatin Impurity 8 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-1,2-dihydro-6-(1-Methylethyl)-2-oxo-, Methyl ester

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PROPIONYLACETIC ACID ETHYL ESTER 3-oxo-pentanoicacidethylester Ethyl 3-oxo-n-valerate Pentanoic acid, 3-oxo-, ethyl ester 3-OXOVALERIC ACID ETHYL ESTER 3-KETOVALERIC ACID ETHYL ESTER 3-KETO-N-VALERIC ACID ETHYL ESTER Rosuvastatin Impurity 96 ETHYL 3-OXOPENTANOATE ETHYL 3-OXOVALERATE ETHYL PROPIONYLACETATE Ethylpropionylacetate,95% Ethyl propionylacetate, 98+% Ethyl propanoylacetate thyl 3-ketopentanoate Ethyl 3-oxovalerate, Ethyl propionylacetate Ethyl propionylacetate, 98+% 5ML Ethyl .beta.-oxovalerate Ethyl 3-Ketopentanoate Ethyl Propioacetate NSC 7251 NSC 78662 Ethyl 3-Oxopentanoate Ethyl Propionylacetate 3-Ketovaleric Acid Ethyl Ester 3-Oxovaleric Acid Ethyl Ester Propionylacetic Acid Ethyl Ester Ethyl3-Oxovalerate> 3-Oxo-pentanoic-5,5,5 acid ethyl ester N-(4-(3-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide 4949-44-4 4949-44-5 4944-44-4 CH3CH2COCH2CO2CH2CH3 CH3CH2COCH2COOC2H5 Organic Building Blocks C6 to C7 Carbonyl Compounds Building Blocks Esters Building Blocks C6 to C7 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Aliphatics Acetics acid and esters C6 to C7 Carbonyl Compounds Esters