(RS)-AMPA
- CAS No.
- 77521-29-0
- Chemical Name:
- (RS)-AMPA
- Synonyms
- AMPA;C13672;AMPA HBR;(RS)-AMPA;(RS)-AMPA hydrobromi;AMPA (ZWITTERION) POTENT EXCITATORY AMI;5-Methyl-3-hydroxy-α-aminoisoxazole-4-propionic acid;2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID;2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- CBNumber:
- CB0714231
- Molecular Formula:
- C7H10N2O4
- Molecular Weight:
- 186.17
- MDL Number:
- MFCD00069214
- MOL File:
- 77521-29-0.mol
- MSDS File:
- SDS
| Melting point | 240 °C |
|---|---|
| Density | 1.386±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: 1.2 mg/mL |
| pka | 2.15±0.10(Predicted) |
| form | solid |
| color | white |
| Water Solubility | Soluble in water (10mM, gentle warming) |
| Stability | Hygroscopic |
| CAS DataBase Reference | 77521-29-0 |
| FDA UNII | J090588E6X |
| EPA Substance Registry System | .alpha.-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (77521-29-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
(RS)-AMPA price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14571 | (R,S)-AMPA ≥99% | 77521-29-0 | 10mg | $119 | 2021-12-16 | Buy |
| Cayman Chemical | 14571 | (R,S)-AMPA ≥99% | 77521-29-0 | 50mg | $536 | 2021-12-16 | Buy |
| TRC | TRC-A634293-5MG | AMPA >95%(HPLC) | 77521-29-0 | 5mg | $542 | 2026-06-03 | Buy |
| TRC | TRC-A634293-1MG | AMPA >95%(HPLC) | 77521-29-0 | 1mg | $164 | 2026-06-03 | Buy |
| TRC | TRC-A634293-10MG | AMPA >95%(HPLC) | 77521-29-0 | 10mg | $903 | 2026-06-03 | Buy |
(RS)-AMPA Chemical Properties, Uses, Production
Chemical Properties
White-to-Off White Powder
Uses
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists
Uses
AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid or NMDA , it can be used to distinguish AMPA receptor-specific activity that contributes to a neuronal response. (R,S)-AMPA contains an equal mixture of the active (S)-enantiomer and the inactive (R)-enantiomer.
Definition
ChEBI: (S)-AMPA is a non-proteinogenic alpha-amino acid.
Biological Activity
More water soluble hydrobromide salt of ( RS )-AMPA ((RS)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid ).
storage
Room temperature
(RS)-AMPA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Shanghai zhigan biotechnology co., LTD | zhiqianbio@126.com | China | 19765 | 58 | |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
