CNQX
- CAS No.
- 115066-14-3
- Chemical Name:
- CNQX
- Synonyms
- CNQX;CNOX;FG-9065;CNQX 2NA;CNQX DISODIUM;C863850 CNQX,≥98%;CNQX DISODIUM SALT;CNQX, 10 mM in DMSO;CNQX disodium salt hydrate;CNQX, AMPA / kainate antagonist
- CBNumber:
- CB0728641
- Molecular Formula:
- C9H4N4O4
- Molecular Weight:
- 232.15
- MDL Number:
- MFCD00069232
- MOL File:
- 115066-14-3.mol
- MSDS File:
- SDS
| Melting point | 300 °C |
|---|---|
| Boiling point | 374.31°C (rough estimate) |
| Density | 1.5507 (rough estimate) |
| refractive index | 1.6590 (estimate) |
| RTECS | VD1520000 |
| storage temp. | protect from light |
| solubility | H2O: 10 mg/mL |
| form | solid |
| pka | 8.16±0.20(Predicted) |
| color | orange to red |
| Water Solubility | H2O: >2mg/mL (warmed) |
| Stability | Store Tightly Sealed at RT |
| CAS DataBase Reference | 115066-14-3(CAS DataBase Reference) |
| FDA UNII | 6OTE87SCCW |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
CNQX price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C127 | CNQX ≥98% (HPLC), solid | 115066-14-3 | 5mg | $167 | 2025-07-31 | Buy |
| Sigma-Aldrich | C127 | CNQX ≥98% (HPLC), solid | 115066-14-3 | 25mg | $589 | 2025-07-31 | Buy |
| Sigma-Aldrich | 5.04914 | CNQX - CAS 115066-14-3 - Calbiochem | 115066-14-3 | 10mg | $181 | 2025-07-31 | Buy |
| TCI Chemical | C3725 | CNQX | 115066-14-3 | 50MG | $216 | 2025-07-31 | Buy |
| Cayman Chemical | 14618 | CNQX ≥98% | 115066-14-3 | 5mg | $50 | 2024-03-01 | Buy |
CNQX Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
Uses
CNQX disodium salt hydrate has been used as:
- as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110)
- as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111)
- as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)
Uses
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
Definition
ChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity
Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol Actions
Potent, competitive AMPA/kainate glutamate receptor antagonist.
storage
Room temperature
CNQX Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12222 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15146 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39030 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from CNQX manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-11 | CNQX
115066-14-3
|
US $41.00-124.00 / mg | 99.70% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-08-25 | 6-Cyano-7-Nitroquinoxaline-2,3-Dione
115066-14-3
|
US $0.00 / kg | 20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | |
 |
2021-08-12 | 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE
115066-14-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- CNQX
115066-14-3
- US $41.00-124.00 / mg
- 99.70%
- TargetMol Chemicals Inc.
-
- 6-Cyano-7-Nitroquinoxaline-2,3-Dione
115066-14-3
- US $0.00 / kg
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE
115066-14-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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