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ChemicalBook >> CAS DataBase List >>7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Structure
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- structure
CAS No.
31170-78-2
Chemical Name:
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
Synonyms
5H-cyclopenta[b]pyridin-7(6H)-one;5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one;7H-cyclopenta[b]pyridin-7-one;5H-Cyclopenta[b]pyridin-7(6H);5,6-Dihydro-[1]pyrindin-7-one;7H-Cyclopenta[b]pyridin-5-one;5H-CYCLOPENTATBPYRIDIN-7(6H)-ONE;5H,6H,7H-cyclopenta[b]pyridin-7-one;5,6-Dihydro-7H-cyclopenta[b]pyridin-7-on;7H-cyclopenta[b]pyridin-5-one,6,7-dihydro-
CBNumber:
CB0735294
Molecular Formula:
C8H7NO
Molecular Weight:
133.15
MDL Number:
MFCD07778341
MOL File:
31170-78-2.mol
MSDS File:
SDS
Last updated:2026-05-27 22:52:13
Product description Number Pack Size Price
5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one 162005 100mg $418
5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% OR951739 100mg $21
5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% OR951739 250mg $24
5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% OR951739 1g $40
5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% OR951739 5g $168
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7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Properties

Melting point 118-120 °C
Boiling point 130-150 °C(Press: 0.1 Torr)
Density 1.230±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 3.50±0.20(Predicted)
Appearance Gray to dark gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933998090

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 162005 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one 31170-78-2 100mg $418 2026-06-03 Buy
Apolloscientific OR951739 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% 31170-78-2 100mg $21 2026-06-04 Buy
Apolloscientific OR951739 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% 31170-78-2 250mg $24 2026-06-04 Buy
Apolloscientific OR951739 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% 31170-78-2 1g $40 2026-06-04 Buy
Apolloscientific OR951739 5,6-Dihydro-7h-cyclopenta[b]pyridin-7-one 97% 31170-78-2 5g $168 2026-06-04 Buy
Product number Packaging Price Buy
162005 100mg $418 Buy
OR951739 100mg $21 Buy
OR951739 250mg $24 Buy
OR951739 1g $40 Buy
OR951739 5g $168 Buy

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Chemical Properties,Uses,Production

Uses

5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one, is an intermediate for the synthesis of pharmaceutical and biological compounds. It can be used for synthesis of new propargylated 1-pyrindane derivatives as Rasagiline (R126000) analogues, used as an antiparkinsonian agent.

Synthesis

(Z)-7-benzylidene-6,7-dihydro-5H-cyclopenta[b]pyridine

74701-35-2

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-

31170-78-2

General procedure for the synthesis of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one from the compound (CAS: 74701-35-2): 5-benzylidene-6,7-dihydro-5H-[1]pyrazine (12.18 g, 58.8 mmol) was dissolved in 200 mL of mixed solvent of MeOH:CH2Cl2 (1:1), and the ozonolysis reaction was performed at 7 psi and 1.5 amperes for the ozonolysis reaction. Upon completion of the reaction, the reaction mixture was quenched with thiourea, filtered and concentrated. The product was purified by column chromatography using hexane:EtOAc (4:1) as eluent to afford 5.96 g (76% yield) of 5,6-dihydro-7H-cyclopenta[b]pyridin-7-one. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.75-2.82 (m, 2H), 3.15-3.22 (m, 2H), 7.47 (q, J = 4.40, 3.52 Hz, 1H), 7.91 (d, J = 8.79 Hz, 1H), 8.79 (d, J = 5.28 Hz, 1H).

References

[1] Patent: US2008/255239, 2008, A1. Location in patent: Page/Page column 32
[2] Journal of Organic Chemistry, 1984, vol. 49, # 12, p. 2208 - 2212
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Preparation Products And Raw materials

Raw materials

(Z)-7-benzylidene-6,7-dihydro-5H-cyclopenta[b]pyridine Oxygen Dichloromethane Ozone Methanol
Thiourea

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Preparation Products

5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Suppliers

Global( 122)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
Zhengzhou Alfa Chemical Co.,Ltd 		+86-18530059196 sale04@alfachem.cn China 9714 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-17392587031 1059@dideu.com China 9983 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9035 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490 info@gihichemicals.com China 49860 58
Changzhou AniKare Pharmatech Co., Ltd. 		+86-0519-8359-8696 sales@anikare.com China 9993 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Baoji Guokang Healthchem Co., Ltd. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
Changzhou AniKare Pharmatech Co., Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58

View Lastest Price from 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2025-06-25 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2021-07-13 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- pictures 2021-07-10 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-
31170-78-2
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- Spectrum

7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-(31170-78-2)1HNMR

31170-78-2(7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO-)Related Search:

5,6-DIHYDRO-4H-CYCLOPENTATHIAZOL-2-YLAMINE 5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-2-CARBOXYLIC ACID Tranexamic acid 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- 5H-CYCLOPENTA[B]PYRIDIN-7-OL, 6,7-DIHYDRO-
5H-Cyclopenta[b]pyridin-7-ol, 6,7-dihydro,(7R)-

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7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- 7H-cyclopenta[b]pyridin-5-one,6,7-dihydro- 7H-Cyclopenta[b]pyridin-5-one 5H,6H,7H-cyclopenta[b]pyridin-7-one 5,6-Dihydro-[1]pyrindin-7-one 5H-Cyclopenta[b]pyridin-7(6H) 7H-cyclopenta[b]pyridin-7-one 7H-CYCLOPENTA[B]PYRIDIN-7-ONE, 5,6-DIHYDRO- ISO 9001：2015 REACH 5H-CYCLOPENTATBPYRIDIN-7(6H)-ONE 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-on 5,6-Dihydro-7H-cyclopenta[b]pyridin-7-one 5H-cyclopenta[b]pyridin-7(6H)-one 31170-78-2 Pyridine Derivertives