ChemicalBook >> CAS DataBase List >>CP 346086 Dihydrate
CP 346086 Dihydrate
- CAS No.
- 1262769-98-1
- Chemical Name:
- CP 346086 Dihydrate
- Synonyms
- CBNumber:
- CB08027520
- Molecular Formula:
- C26H24F3N5O2
- Molecular Weight:
- 495.51
- MDL Number:
- MOL File:
- 1262769-98-1.mol
- MSDS File:
- SDS
Last updated:2025-04-17 18:22:24
CP 346086 Dihydrate Chemical Properties, Uses, Production
Uses
CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity.
in vivo
CP-346086 (1-100 mg/kg; oral gavage once daily for 2 weeks) reduces plasma total, VLDL, and LDL cholesterol and triglycerides in mice[1].
CP-346086 (25 mg/kg; a single p.o.) results in an almost complete inhibition of Tyloxapol-induced triglyceride accumulation in fasted rats[1].
CP-346086 (0.1-10 mg/kg; a single p.o.) reduces acute plasma triglyceride in mice[1].
| Animal Model: | B6CBAF1J mice[1] |
| Dosage: | 1, 2, 10, 20, 100 mg/kg |
| Administration: | Oral gavage once daily for 2 weeks |
| Result: | Lowered total, VLDL, and LDL cholesterol and triglycerides dose dependently with 23%, 33%, 75%, and 62% reductions at 10 mg/kg/day. |
CP 346086 Dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
CP 346086 Dihydrate Suppliers
Global Suppliers ( 6)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai Merlot Chemical Co., LTD | 15821661757 | 226174156@qq.com | China | 476 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| Guangzhou Isun Pharmaceutical Co., Ltd | 55 |
| Shanghai Merlot Chemical Co., LTD | 58 |
| TargetMol Chemicals Inc. | 58 |
1262769-98-1 (CP 346086 Dihydrate) Related Search:
1262769-98-1
