BMT-124110
- CAS No.
- 1679371-59-5
- Chemical Name:
- BMT-124110
- Synonyms
- BMT-124110;BMT 124110,BMT124110;BMT-124110, 10 mM in DMSO;Acetamide, N-[8-[[(2S)-2-amino-2,4-dimethylpentyl]oxy]-5H-[1]benzopyrano[3,4-c]pyridin-2-yl]-
- CBNumber:
- CB08054331
- Molecular Formula:
- C21H27N3O3
- Molecular Weight:
- 369.46
- MDL Number:
- MFCD34469994
- MOL File:
- 1679371-59-5.mol
BMT-124110 Chemical Properties,Uses,Production
Uses
BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively[1].
in vivo
BMT-124110 is added directly onto the spinal corevd by microiontophoresis, leading to reduction in windup-induced activity in 10 of 14 animals[1].
References
[1] Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86. DOI:10.1124/jpet.116.235333
BMT-124110 Preparation Products And Raw materials
Raw materials
Preparation Products
BMT-124110 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19961 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29545 | 58 |
| Anhui JYHX CO., LTD. | 0551-68788198 13295518198 | wangyanan@ahjyhx.com | China | 1759 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-58851090 17714375163 | 2881759498@qq.com | China | 13011 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 6710 | 58 |
View Lastest Price from BMT-124110 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-16 | BMT-124110
1679371-59-5
|
US $329.00-1090.00 / mg | 98.07% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-28 | BMT-124110
1679371-59-5
|
US $329.00-1090.00 / mg | 98.93% | 10g | TargetMol Chemicals Inc. |
-
- BMT-124110
1679371-59-5
- US $329.00-1090.00 / mg
- 98.07%
- TargetMol Chemicals Inc.
-
- BMT-124110
1679371-59-5
- US $329.00-1090.00 / mg
- 98.93%
- TargetMol Chemicals Inc.
