ChemicalBook >> CAS DataBase List >>Tubulin inhibitor 6
Tubulin inhibitor 6
- CAS No.
- 105925-39-1
- Chemical Name:
- Tubulin inhibitor 6
- Synonyms
- iHAP1;Tubulin inhibitor 6;iHAP1 （Tubulin inhibitor 6）;Tubulin inhibitor 6, 10 mM in DMSO;2-chloro-10-(4-methoxybenzoyl)-10H-phenothiazine;2-chloro-10-(4-methoxybenzeneformyl)-10H-phenethiazine;(2-chlorophenothiazin-10-yl)-(4-methoxyphenyl)methanone;(2-Chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone;Methanone, (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)-;DLD-1,cycle,K562,Tubulin inhibitor-6,tubulin,COLO-205,SKOV3,Tubulin inhibitor 6,451LU,Inhibitor,Microtubule/Tubulin,Tubulin inhibitor6,SW480,Antiproliferative,inhibit,NCIH460,BT549,cell
- CBNumber:
- CB08054568
- Molecular Formula:
- C20H14ClNO2S
- Molecular Weight:
- 367.85
- MDL Number:
- MOL File:
- 105925-39-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 22:54:07
| Product description | Number | Pack Size | Price |
| iHAP1 ≥98% | 33530 | 1mg | $36 |
| iHAP1 ≥98% | 33530 | 5mg | $103 |
| iHAP1 ≥98% | 33530 | 10mg | $169 |
| iHAP1 ≥98% | 33530 | 25mg | $378 |
| Tubulin inhibitor 6 98.97% | CS-0119638 | 5mg | $65 |
| Melting point | 155-157 °C |
|---|---|
| Boiling point | 549.1±50.0 °C(Predicted) |
| Density | 1.364±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 62.5 mg/mL (169.91 mM) |
| form | A crystalline solid |
| pka | -5.56±0.20(Predicted) |
| color | White to off-white |
| InChIKey | CSWHYHPUEDNIQY-UHFFFAOYSA-N |
| SMILES | S1c2c(cc(cc2)Cl)N(c4c1cccc4)C(=O)c3ccc(cc3)OC |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H335-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
Tubulin inhibitor 6 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 33530 | iHAP1 ≥98% | 105925-39-1 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 33530 | iHAP1 ≥98% | 105925-39-1 | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 33530 | iHAP1 ≥98% | 105925-39-1 | 10mg | $169 | 2026-04-30 | Buy |
| Cayman Chemical | 33530 | iHAP1 ≥98% | 105925-39-1 | 25mg | $378 | 2026-04-30 | Buy |
| ChemScene | CS-0119638 | Tubulin inhibitor 6 98.97% | 105925-39-1 | 5mg | $65 | 2026-06-04 | Buy |
Tubulin inhibitor 6 Chemical Properties,Uses,Production
Uses
Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].
Biological Activity
Tubulin inhibitor 6 is an activator of protein phosphatase 2A (PP2A) enzymes that activates PP2A-B56ε and efficiently kills malignant cells.
in vitro
Tubulin inhibitor 6 displays submicromolar antiproliferative activity.
target
| Target | Value | |||||||
| PP2A () |
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9949 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4841 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
View Lastest Price from Tubulin inhibitor 6 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Tubulin inhibitor 6
105925-39-1
|
$30.00-83.00 | 99.53% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-22 | Tubulin inhibitor 6
105925-39-1
|
$30.00-83.00 | 99.53% | 10g | TargetMol Chemicals Inc. |
-
- Tubulin inhibitor 6
105925-39-1
- $30.00-83.00
- 99.53%
- TargetMol Chemicals Inc.
-
- Tubulin inhibitor 6
105925-39-1
- $30.00-83.00
- 99.53%
- TargetMol Chemicals Inc.
Tubulin inhibitor 6
iHAP1
Methanone, (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)-
(2-Chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone
DLD-1,cycle,K562,Tubulin inhibitor-6,tubulin,COLO-205,SKOV3,Tubulin inhibitor 6,451LU,Inhibitor,Microtubule/Tubulin,Tubulin inhibitor6,SW480,Antiproliferative,inhibit,NCIH460,BT549,cell
iHAP1
（Tubulin inhibitor 6）
(2-chlorophenothiazin-10-yl)-(4-methoxyphenyl)methanone
2-chloro-10-(4-methoxybenzoyl)-10H-phenothiazine
Tubulin inhibitor 6, 10 mM in DMSO
2-chloro-10-(4-methoxybenzeneformyl)-10H-phenethiazine
105925-39-1
