2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
- CAS No.
- 2320560-36-7
- Chemical Name:
- 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
- Synonyms
- 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
- CBNumber:
- CB08054649
- Molecular Formula:
- C26H38N6O14
- Molecular Weight:
- 658.62
- MDL Number:
- MFCD32069531
- MOL File:
- 2320560-36-7.mol
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | bp-24336 | 2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) 95% | 2320560-36-7 | 25MG | $350 | 2026-05-24 | Buy |
| BroadPharm | bp-24336 | 2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) 95% | 2320560-36-7 | 50MG | $580 | 2026-05-24 | Buy |
| BroadPharm | bp-24336 | 2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) 95% | 2320560-36-7 | 100MG | $980 | 2026-05-24 | Buy |
| BroadPharm | bp-24336 | 2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) 95% | 2320560-36-7 | 250MG | $1630 | 2026-05-24 | Buy |
| aablocks | AA01JOS1 | 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) ≥95% | 2320560-36-7 | 25mg | $483 | 2026-05-30 | Buy |
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Chemical Properties, Uses, Production
Description
2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) is a branched PEGylation reagent. The azide groups enable PEGylation via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The PEG spacer allows for enhanced hydrophilic properties.
Uses
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com 18017580634 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Affinity Linkers Ltd. | 15841022315 15841022315 | sales@affinitytech.cn | China | 7039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
