Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)
- CAS No.
- 1854126-47-8
- Chemical Name:
- Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)
- Synonyms
- HydroxychloroquineSulfateEPImpurityC-d4;2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-ethan-1,1,2,2-d4-ol;Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4)
- CBNumber:
- CB08176204
- Molecular Formula:
- C16H22ClN3O
- Molecular Weight:
- 307.82
- MDL Number:
- MOL File:
- 1854126-47-8.mol
- MSDS File:
- SDS
Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 31162 | Desethyl Hydroxychloroquine-d4 ≥99%deuteratedforms(d1-d4) | 1854126-47-8 | 500μg | $182 | 2026-04-30 | Buy |
| Cayman Chemical | 31162 | Desethyl Hydroxychloroquine-d4 ≥99%deuteratedforms(d1-d4) | 1854126-47-8 | 1mg | $327 | 2026-04-30 | Buy |
| Cayman Chemical | 31162 | Desethyl Hydroxychloroquine-d4 ≥99%deuteratedforms(d1-d4) | 1854126-47-8 | 5mg | $1089 | 2026-04-30 | Buy |
| Biosynth | EZC12647 | Desethyl hydroxychloroquine-d4 | 1854126-47-8 | 5mg | $1919.45 | 2026-06-04 | Buy |
| Biosynth | EZC12647 | Desethyl hydroxychloroquine-d4 | 1854126-47-8 | 10mg | $3071.1 | 2026-06-04 | Buy |
Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4) Chemical Properties, Uses, Production
Uses
Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].
Biological Activity
Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1 It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
IC 50
Plasmodium
References
1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)
Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4) Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxychloroquine Sulfate EP Impurity C-d4 (Desethyl Hydroxy Chloroquine-d4) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9382 | 58 |
| Jinan blalong chemical co. LTD | 2710913286@qq.com | 1513643261@qq.com | China | 14227 | 58 |
| ChemeGen | 18818260767 | 2625930290@qq.com | China | 6966 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7982 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 | chinasales04@tlcstandards.com.cn | China | 8143 | 58 |
