1-(4-amino-3-fluorophenyl)ethan-1-one
- CAS No.
- 73792-22-0
- Chemical Name:
- 1-(4-amino-3-fluorophenyl)ethan-1-one
- Synonyms
- 4-Acetyl-2-fluoroaniline;3-Fluoro-4-aminoacetophenone;4’-Amino-3’-fluoroacetophenone;4'-Amino-3'-fluoroacetophenone;1-(4-Amino-3-fluorophenyl)ethanone;1-(4-amino-3-fluorophenyl)ethan-1-one;Ethanone, 1-(4-amino-3-fluorophenyl)-;Ethanone, 1-(4-amino-3-fluorophenyl)- (9CI)
- CBNumber:
- CB0883289
- Molecular Formula:
- C8H8FNO
- Molecular Weight:
- 153.15
- MDL Number:
- MFCD12032124
- MOL File:
- 73792-22-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(4-Amino-3-fluorophenyl)ethanone >98% | PC201298 | 1g | $21 |
| 1-(4-Amino-3-fluorophenyl)ethanone >98% | PC201298 | 5g | $25 |
| 1-(4-Amino-3-fluorophenyl)ethanone >98% | PC201298 | 25g | $104 |
| 1-(4-Amino-3-fluorophenyl)ethanone >98% | PC201298 | 100g | $368 |
| 1-(4-Amino-3-fluorophenyl)ethanone >98% | PC201298 | 500g | $1800 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H302-H335-H312-H332 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312 |
| HS Code | 2914790090 |
1-(4-amino-3-fluorophenyl)ethan-1-one price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC201298 | 1-(4-Amino-3-fluorophenyl)ethanone >98% | 73792-22-0 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC201298 | 1-(4-Amino-3-fluorophenyl)ethanone >98% | 73792-22-0 | 5g | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC201298 | 1-(4-Amino-3-fluorophenyl)ethanone >98% | 73792-22-0 | 25g | $104 | 2026-06-04 | Buy |
| Apolloscientific | PC201298 | 1-(4-Amino-3-fluorophenyl)ethanone >98% | 73792-22-0 | 100g | $368 | 2026-06-04 | Buy |
| Apolloscientific | PC201298 | 1-(4-Amino-3-fluorophenyl)ethanone >98% | 73792-22-0 | 500g | $1800 | 2026-06-04 | Buy |
1-(4-amino-3-fluorophenyl)ethan-1-one Chemical Properties,Uses,Production
Uses
1-(4-Amino-3-fluorophenyl)ethanone can be used as a starting material in the preparation of 2-Amino-5-[(cyclopentylamino)acetyl]-3-fluoro-benzonitrile.
Synthesis
111-34-2
29632-74-4
73792-22-0
Example 7: Synthesis of (R)-N-(4-{1-[3-(4-tert-butyl-benzyl)-ureido]-ethyl}-2-fluoro-6-vinyl-phenyl)-methanesulfonamide; Step i: Preparation of 1-(4-amino-3-fluorophenyl)ethanone. In a 25 mL two-necked round-bottomed flask, filled with argon protection, a DMF solution of 2-fluoro-4-iodoaniline (1500 mg, 6.33 mmol) was added. Palladium(II) acetate (42.62 mg, 0.19 mmol), 1,3-bis(diphenylphosphino)propane (156.65 mg, 0.38 mmol, 0.06 equiv.), thallium(I) acetate (1834.19 mg, 6.96 mmol), and butyl vinyl ether (1.64 mL, 12.66 mmol, 2 equiv.) were then added sequentially. The reaction mixture was heated and stirred for 15 hours. After the reaction was completed, the mixture was poured into THF and 10% HCl solution was added slowly. The reaction mixture was extracted with ethyl acetate (300 mL x 3) and the organic phases were combined and washed sequentially with water and brine. The organic layer was dried with anhydrous Na2SO4, filtered and purified by column chromatography (n-hexane: ethyl acetate=3:1) to give a light yellow solid product (343.0 mg, yield 35.40%). Melting point: 77-79°C; IR (KBr pressed sheet, cm^-1): 3373, 3326, 1663, 1296; 1H NMR (400 MHz, CDCl3): δ 7.53 (m, 2H), 6.69 (m, 1H), 3.41 (s, 2H), 2.43 (s, 3H).
References
[1] Patent: WO2006/101318, 2006, A1. Location in patent: Page/Page column 44; 83-84
[2] Patent: EP1862454, 2007, A1. Location in patent: Page/Page column 6; 18
1-(4-amino-3-fluorophenyl)ethan-1-one Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 1-(4-amino-3-fluorophenyl)ethan-1-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 1-(4-amino-3-fluorophenyl)ethan-1-one
73792-22-0
|
$2.00 | 1kg | 99% | 100kg | Career Henan Chemical Co |
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- 1-(4-amino-3-fluorophenyl)ethan-1-one
73792-22-0
- $2.00
- 99%
- Career Henan Chemical Co
