amiphenazole
- CAS No.
- 490-55-1
- Chemical Name:
- amiphenazole
- Synonyms
- Daftazol;Daptazile;Amifenazol;Phenamizol;Amiphenazol;Phenamizole;Amifenazole;amiphenazole;Amifenazol [inn-spanish];2,4-Diamino-5-phenylthiazole
- CBNumber:
- CB0909615
- Molecular Formula:
- C9H9N3S
- Molecular Weight:
- 191.25
- MDL Number:
- MFCD00128273
- MOL File:
- 490-55-1.mol
| Product description | Number | Pack Size | Price |
| 5-Phenylthiazole-2,4-diamine 97% | CD11117196 | 1g | $90 |
| 5-Phenylthiazole-2,4-diamine 97% | CD11117196 | 5g | $270 |
| 5-Phenylthiazole-2,4-diamine 97% | CD11117196 | 10g | $450 |
| 5-Phenylthiazole-2,4-diamine 97% | CD11117196 | 25g | $880 |
| More product size | |||
| Melting point | 163.5°C (rough estimate) |
|---|---|
| Boiling point | 413.3±25.0 °C(Predicted) |
| Density | 1.1906 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| pka | 5.12±0.10(Predicted) |
| FDA UNII | 7ZJ8PWY0XD |
amiphenazole price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD11117196 | 5-Phenylthiazole-2,4-diamine 97% | 490-55-1 | 1g | $90 | 2021-12-16 | Buy |
| Crysdot | CD11117196 | 5-Phenylthiazole-2,4-diamine 97% | 490-55-1 | 5g | $270 | 2021-12-16 | Buy |
| Crysdot | CD11117196 | 5-Phenylthiazole-2,4-diamine 97% | 490-55-1 | 10g | $450 | 2021-12-16 | Buy |
| Crysdot | CD11117196 | 5-Phenylthiazole-2,4-diamine 97% | 490-55-1 | 25g | $880 | 2021-12-16 | Buy |
amiphenazole Chemical Properties,Uses,Production
Originator
Aamphisol,RJR
Definition
ChEBI: Amiphenazole is a member of thiazoles.
Manufacturing Process
Thiourea reacted with α-bromophenylacetonitrile and as a result of this
reaction 2-(cyanophenylmethyl)isothiourea was obtained.
By cyclisation of the 2-(cyanophenylmethyl)isothiourea 2,4-diamino-5-
phenylthiazole (amiphenazol) was produced.
Therapeutic Function
Respiratory stimulant, Barbiturate antagonist, Morphine antagonist
Synthesis Reference(s)
Journal of the American Chemical Society, 73, p. 4517, 1951 DOI: 10.1021/ja01154a005
Purification Methods
The thiazole crystallises from aqueous EtOH or water. Store it in the dark under N2. The hydrochloride has m 273-274o(dec) (from MeOH/EtOAc), and the picrate has m 189-191o(dec) (from H2O). [Davies et al. J Chem Soc 3491 1950, Dodson & Turner J Am Chem Soc 73 4517 1951, Beilstein 27 III/IV 5139.]
amiphenazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 4069 | 55 |
| Candia Thamtech Company Limited | 0371-86615086 18203638366 0371-86159066 13526786601 | China | 2015 | 60 | |
| Tianjing Geneston Bio-tech Co.,Ltd. | 022-60131465 18920720807 | zishan_1986@163.com | China | 743 | 58 |
| Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | 2853283383@qq.com | China | 11421 | 58 |
| Supplier | Advantage |
|---|---|
| Wuhan TCASChem Technology Co., Ltd. | 55 |
| Candia Thamtech Company Limited | 60 |
| Tianjing Geneston Bio-tech Co.,Ltd. | 58 |
| Cato Research Chemicals Inc. | 58 |
