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ChemicalBook >> CAS DataBase List >>2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Structure
2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one structure
CAS No.
17952-82-8
Chemical Name:
2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one
Synonyms
1,2,3,4-Tetrahydronorharman-1-one;3,4-Dihydro-β-carboline-1(2H)-one;1,2,3,4-Tetrahydro-β-carboline-1-one;2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one;2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one;1,2,3,4-Tetrahydronorharman-1-one, 10 mM in DMSO;1H-Pyrido[3,4-b]indol-1-one, 2,3,4,9-tetrahydro-
CBNumber:
CB0915201
Molecular Formula:
C11H10N2O
Molecular Weight:
186.21
MDL Number:
MOL File:
17952-82-8.mol
MSDS File:
SDS
Last updated:2026-05-27 23:00:20
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2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Properties

Melting point 183-185 °C
Boiling point 529.2±39.0 °C(Predicted)
Density 1.318±0.06 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Cryst.
pka 15.48±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth SAA95282 2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-one 17952-82-8 250mg $307.5 2026-06-05 Buy
Biosynth SAA95282 2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-one 17952-82-8 2.5g $1386.5 2026-06-05 Buy
ChemScene CS-0313669 1,2,3,4-Tetrahydronorharman-1-one ≥98% 17952-82-8 100mg $80 2026-06-04 Buy
ChemScene CS-0313669 1,2,3,4-Tetrahydronorharman-1-one ≥98% 17952-82-8 250mg $130 2026-06-04 Buy
ChemScene CS-0313669 1,2,3,4-Tetrahydronorharman-1-one ≥98% 17952-82-8 1g $283 2026-06-04 Buy
Product number Packaging Price Buy
SAA95282 250mg $307.5 Buy
SAA95282 2.5g $1386.5 Buy
CS-0313669 100mg $80 Buy
CS-0313669 250mg $130 Buy
CS-0313669 1g $283 Buy

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Chemical Properties, Uses, Production

Uses

1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid with activity against infectious and tropical parasitic diseases from an Indonesian sponge[1].

Preparation

Tryptamine 380 (9.0 g, 56.2 mmol) and triethylamine (13.8 g, 136.3 mmol) were dissolved in warm toluene (800 mL). Under vigorous stirring, a solution of triphosgene (6.7 g, 22.6 mmol) in toluene (35 mL) was added dropwise and the mixture was stirred for a further 20 min at room temperature. Then, HBr (30% in acetic acid; 13 mL) was added and the mixture was refluxed for 30 min. After cooling to room temperature, water (300 mL) and ethyl acetate (300 mL) were added and, after separation of the layers, the aqueous phase was extracted once more with ethyl acetate (300 mL). The combined organic layers were dried over magnesium sulfate and concentrated in vacuo. The residue was recrystallized from methanol/ethyl acetate (1:1) to afford 7.74 g (74%) of 2,3,4,9-tetrahydro-1H-pyrido[ 3,4-b]indol-1-one 382 as a white solid; mp 184°C.

References

[1] Karumanchi V Rao, et al. New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. J Nat Prod. 2003 Jun;66(6):823-8. DOI:10.1021/np020592u

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one 2,9-dihydropyrido[3,4-b]indol-1-one

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Suppliers

Global Suppliers ( 46)
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Tombiopharma Chemical Co. Ltd. 13391076197 tombiopharma@163.com China 4986 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563 3905209149@qq.com China 9715 58
Accela ChemBio Inc. +1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Supplier Advantage
Accela ChemBio Co.,Ltd. 64
Shanghai Tombiopharma Chemical Co. Ltd. 55
Wuhan ChemFaces Biochemical Co., Ltd. 55
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Aikon International Limited 58
TargetMol Chemicals Inc. 58
Henan Weituxi Chemical Technology Co., Ltd. 58
Accela ChemBio Inc. 58

View Latest Price from 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2,3,4-Tetrahydronorharman-1-one pictures 2026-04-22 1,2,3,4-Tetrahydronorharman-1-one
17952-82-8
 $50.00-128.00 99.88% 10g TargetMol Chemicals Inc.

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one Spectrum

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one(17952-82-8)1HNMR

17952-82-8 (2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one ) Related Search:

1-Oxo-2,3,4,9-tetrahydro-1H-B-carboline-6-carboxylic acid ethyl ester 6-Nitro-2,3,4,9-tetrahydro-1H-beta-carbolin-1-one 6-Methyl-2,3,4,9-tetrahydro-1H-beta-carbolin-1-one 6-Iodo-2,3,4,9-tetrahydro-β-carbolin-1-one 1-Oxo-2,3,4,9-tetrahydro-1H-B-carboline-6-carboxylic acid
6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one 2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-one AKOS BB-9342 AKOS BB-9155 B 193
AKOS BB-9343 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one 1H-Pyrido(3,4-b)indole-1,3(2H)-dione, 4,9-dihydro-2-(2-(4-(2-pyrimidin yl)-1-piperazinyl)ethyl)-

1of3

2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one 1,2,3,4-Tetrahydro-β-carboline-1-one 3,4-Dihydro-β-carboline-1(2H)-one 1,2,3,4-Tetrahydronorharman-1-one 1H-Pyrido[3,4-b]indol-1-one, 2,3,4,9-tetrahydro- 2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one 1,2,3,4-Tetrahydronorharman-1-one, 10 mM in DMSO 17952-82-8