N2-methylpyridine-2,5-diamine
- CAS No.
- 28020-36-2
- Chemical Name:
- N2-methylpyridine-2,5-diamine
- Synonyms
- 2-Methylamino-5-pyridinamine;N2-Methyl-2,5-PyridinediaMine;2-N-METHYLPYRIDINE-2,5-DIAMine;2,5-PyridinediaMine, N2-Methyl-
- CBNumber:
- CB0937685
- Molecular Formula:
- C6H9N3
- Molecular Weight:
- 123.16
- MDL Number:
- MFCD08692343
- MOL File:
- 28020-36-2.mol
- MSDS File:
- SDS
| Boiling point | 306.4±22.0 °C(Predicted) |
|---|---|
| Density | 1.179±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 7.56±0.10(Predicted) |
| FDA UNII | HXK5ZQ4B8F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
N2-methylpyridine-2,5-diamine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DBA02036 | N2-Methylpyridine-2,5-diamine | 28020-36-2 | 2.5g | $442.5 | 2026-06-04 | Buy |
| Activate Scientific | AS44317 | N2-Methylpyridine-2,5-diamine 98% | 28020-36-2 | 1g | $152 | 2026-06-04 | Buy |
| Activate Scientific | AS44317 | N2-Methylpyridine-2,5-diamine 98% | 28020-36-2 | 5g | $506 | 2026-06-04 | Buy |
| Matrix Scientific | 303898 | N2-Methylpyridine-2,5-diamine | 28020-36-2 | 250.00mg | $60 | 2026-05-19 | Buy |
| Matrix Scientific | 303898 | N2-Methylpyridine-2,5-diamine | 28020-36-2 | 1.00g | $119 | 2026-05-19 | Buy |
N2-methylpyridine-2,5-diamine Chemical Properties, Uses, Production
Synthesis
4093-89-4
28020-36-2
GENERAL METHOD: 2-chloro-5-nitropyridine (50 mmol), morpholine (100 mmol), and K2CO3 (100 mmol) were dissolved in THF (50 mL), and the reaction was stirred at 80 °C for 4 hours. Upon completion of the reaction, the mixture was concentrated to 20 mL and subsequently poured into water (100 mL) to precipitate a yellow solid precipitate. After filtration, washing with pure water and drying, the target compound 3a was obtained.Compound 3b was prepared by the same method. Compounds 3a-3b (20 mmol) were mixed with Pd/C (20%, 500 mg) in methanol and subjected to hydrogenation reaction for 12 h at room temperature. At the end of the reaction, the reaction solution was filtered and concentrated to obtain the target compounds 4a-4b.
References
[1] Chinese Chemical Letters, 2016, vol. 27, # 1, p. 1 - 6
[2] Patent: WO2005/28452, 2005, A1. Location in patent: Page/Page column 94
[3] Patent: WO2006/100588, 2006, A1. Location in patent: Page/Page column 63
[4] Journal of Medicinal Chemistry, 1994, vol. 37, # 1, p. 18 - 25
[5] Patent: US2012/258951, 2012, A1. Location in patent: Page/Page column 77
N2-methylpyridine-2,5-diamine Preparation Products And Raw materials
N2-methylpyridine-2,5-diamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443;18052965989 | tongbenwan22@163.com | China | 1975 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Chengdu Saiousi Pharmaceutical Co., Ltd | 028-64971018 18108168130 | China | 1780 | 55 | |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
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