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ChemicalBook >> CAS DataBase List >>Dhodh-IN-16

Dhodh-IN-16

Dhodh-IN-16 Structure
Dhodh-IN-16 structure
CAS No.
2511248-11-4
Chemical Name:
Dhodh-IN-16
Synonyms
DHODH-IN-16;DHODH-IN-16, 10 mM in DMSO;DNA/RNA Synthesis,inhibit,Dihydroorotate Dehydrogenase,Inhibitor,antiproliferative,DHODH IN 16,DHODH,DHODHIN16;6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one;1(2H)-Isoquinolinone, 6-[4-ethyl-4,5-dihydro-3-(hydroxymethyl)-5-oxo-1H-1,2,4-triazol-1-yl]-7-fluoro-4-(1-methylethyl)-2-(2-methylphenyl)-;6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-7-fluoro-2-(2-methylphenyl)-4-(propan-2-yl)-1,2-dihydroisoquinolin-1-one
CBNumber:
CB09441217
Molecular Formula:
C24H25FN4O3
Molecular Weight:
436.48
MDL Number:
MOL File:
2511248-11-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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Dhodh-IN-16 Properties

Boiling point 602.6±65.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (229.11 mM; Need ultrasonic)
pka 13.54±0.10(Predicted)
form Solid
color White to off-white

Dhodh-IN-16 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0181689 JNJ-74856665 99.74% 2511248-11-4 5mg $233 2026-06-04 Buy
ChemScene CS-0181689 JNJ-74856665 99.74% 2511248-11-4 10mg $368 2026-06-04 Buy
ChemScene CS-0181689 JNJ-74856665 99.74% 2511248-11-4 25mg $704 2026-06-04 Buy
ChemScene CS-0181689 JNJ-74856665 99.74% 2511248-11-4 50mg $1029 2026-06-04 Buy
ChemScene CS-0181689 JNJ-74856665 99.74% 2511248-11-4 100mg $1462 2026-06-04 Buy
Product number Packaging Price Buy
CS-0181689 5mg $233 Buy
CS-0181689 10mg $368 Buy
CS-0181689 25mg $704 Buy
CS-0181689 50mg $1029 Buy
CS-0181689 100mg $1462 Buy

Dhodh-IN-16 Chemical Properties, Uses, Production

Uses

DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].

Biological Activity

DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1]. DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM[1].

References

[1]. Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1.

Dhodh-IN-16 Preparation Products And Raw materials

Raw materials

Preparation Products

Dhodh-IN-16 Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Shanghai XingMo Biotechnology Co., Ltd. +86 13524779951; 13524779951 2075692521@qq.com China 294 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465 sales@zehanbiopharma.com China 989 55
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Dezhou LonWel Pharmaceutical Technology Co., Ltd. 13761310616 39324283@qq.com China 1365 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Supplier Advantage
Finetech Industry Limited 58
Shanghai XingMo Biotechnology Co., Ltd. 55
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghaizehan biopharma technology co., Ltd. 55
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Dezhou LonWel Pharmaceutical Technology Co., Ltd. 58
BOC Sciences 58
TargetMol Chemicals Inc. 58

View Latest Price from Dhodh-IN-16 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DHODH-IN-16 pictures 2026-07-14 DHODH-IN-16
2511248-11-4
 $69.00-172.00 99.64% 10g TargetMol Chemicals Inc.
  • DHODH-IN-16 pictures
  • DHODH-IN-16
    2511248-11-4
  • $69.00-172.00
  • 99.64%
  • TargetMol Chemicals Inc.

Dhodh-IN-16 Spectrum

Dhodh-IN-16(2511248-11-4)1HNMR

2511248-11-4 (Dhodh-IN-16) Related Search:

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1of2

6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one DHODH-IN-16 DNA/RNA Synthesis,inhibit,Dihydroorotate Dehydrogenase,Inhibitor,antiproliferative,DHODH IN 16,DHODH,DHODHIN16 1(2H)-Isoquinolinone, 6-[4-ethyl-4,5-dihydro-3-(hydroxymethyl)-5-oxo-1H-1,2,4-triazol-1-yl]-7-fluoro-4-(1-methylethyl)-2-(2-methylphenyl)- 6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-7-fluoro-2-(2-methylphenyl)-4-(propan-2-yl)-1,2-dihydroisoquinolin-1-one DHODH-IN-16, 10 mM in DMSO 2511248-11-4