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4-(4-Chlorophenyl)butanoic acid

4-(4-Chlorophenyl)butanoic acid structure

CAS No.: 4619-18-5

Chemical Name:: 4-(4-Chlorophenyl)butanoic acid

Synonyms: 4-Chlorobenzenebutanoic acid;-(4-Chlorophenyl)butanic acid;4-(4-Chlorophenyl)butanic acid;Benzenebutanoic acid, 4-chloro-;4-(4-chlorophenyl)butanoic acid;4-(4-CHLORO-PHENYL)-BUTYRIC ACID;4-(4-chlorophenyl)butanoic acid(SALTDATA: FREE)

CBNumber:: CB0958426

Molecular Formula:: C10H11ClO2

Molecular Weight:: 198.65

MDL Number:: MFCD06810494

MOL File:: 4619-18-5.mol

Last updated:2025-07-24 18:13:49

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4-(4-Chlorophenyl)butanoic acid Properties

Melting point	55 °C
Boiling point	181-184 °C
Density	1.227±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	4.74±0.10(Predicted)
Appearance	White to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H318-H302
Precautionary statements	P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310
HS Code	29163990

4-(4-Chlorophenyl)butanoic acid price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C994588	4-(4-Chlorophenyl)butyricAcid	4619-18-5	50mg	$45	2021-12-16	Buy
Rieke Metals	C0102	4-(4-Chlorophenyl)butyricacid	4619-18-5	1g	$661	2021-12-16	Buy
Matrix Scientific	177177	4-(4-Chlorophenyl)butanoic acid	4619-18-5	1g	$720	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0055362	4-(4-CHLOROPHENYL)BUTANOIC ACID 95.00%	4619-18-5	1G	$867.1	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0055362	4-(4-CHLOROPHENYL)BUTANOIC ACID 95.00%	4619-18-5	2.5G	$1255.54	2021-12-16	Buy

Product number	Packaging	Price	Buy
C994588	50mg	$45	Buy
C0102	1g	$661	Buy
177177	1g	$720	Buy
HCH0055362	1G	$867.1	Buy
HCH0055362	2.5G	$1255.54	Buy

4-(4-Chlorophenyl)butanoic acid Chemical Properties,Uses,Production

Synthesis

3984-34-7

4619-18-5

General procedure for the synthesis of 4-(4-chlorophenyl)butyric acid from 3-(4-chlorobenzoyl)propionic acid: A mixture of 4-(4-chlorophenyl)-4-oxobutanoic acid (1 eq.), potassium hydroxide (KOH, 3 eq.), and hydrazine hydrate (2.2 eq.) in ethylene glycol was placed in a reaction flask and azeotropically refluxed for 5 hr at 120-130 °C. Subsequently, the reaction temperature was gradually increased to 180 °C and the reflux was continued at 190 °C for 3 hours. After completion of the reaction, the reaction mixture was cooled to 25 °C, diluted with water and poured into 2.5 N hydrochloric acid (HCl) solution for acidification, and white crystals were precipitated to give 4-(4-chlorophenyl)butyric acid in 89% yield.

References

[1] Patent: US6410585, 2002, B1
[2] Journal of Medicinal Chemistry, 1982, vol. 25, # 8, p. 947 - 952
[3] Patent: US2005/165004, 2005, A1. Location in patent: Page/Page column 28
[4] Patent: WO2015/134973, 2015, A1. Location in patent: Page/Page column 97; 98
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 41, p. 12476 - 12480

4-(4-Chlorophenyl)butanoic acid Preparation Products And Raw materials

Raw materials

3-(4-Chlorobenzoyl)propionic acid Ethylene glycol Potassium hydroxide HYDRAZINE

Preparation Products

5-(4-Chlorophenyl)pyrrolidin-2-one 1-Butanone, 4-(4-chlorophenyl)-1-(3,4-dihydro-6,7-dihydroxy-2(1H)-isoquinolinyl)-

4-(4-Chlorophenyl)butanoic acid Suppliers

Global( 74)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8371	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9647	58
Nanjing Hengbei Chemicals Co., Ltd.	+86-25-58393656	sales@hengbeichem.cn	China	6854	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20190	58

Supplier	Advantage
Shanghai UCHEM Inc.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Nextpeptide Inc	58
changzhou huayang technology co., ltd	58
Nanjing Hengbei Chemicals Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58

View Lastest Price from 4-(4-Chlorophenyl)butanoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-18	4-(4-Chlorophenyl)butanoic acid 4619-18-5	US $15.00-125.00 / g	5g	0.98	25kg	Shanghai UCHEM Inc.
2022-01-15	4-(4-Chlorophenyl)butanicacid 4619-18-5	US $0.00 / KG	1KG	98.4%	100 tons	Honest Joy Holdings Limited
2019-07-06	4-(4-Chlorophenyl)butanic acid 4619-18-5	US $10.00-2.00 / KG	1KG	98%	100	Career Henan Chemical Co

4-(4-Chlorophenyl)butanoic acid
4619-18-5
US $15.00-125.00 / g
0.98
Shanghai UCHEM Inc.

4-(4-Chlorophenyl)butanicacid
4619-18-5
US $0.00 / KG
98.4%
Honest Joy Holdings Limited

4-(4-Chlorophenyl)butanic acid
4619-18-5
US $10.00-2.00 / KG
98%
Career Henan Chemical Co

4-(4-Chlorophenyl)butanoic acid Spectrum

4-(4-Chlorophenyl)butanoic acid(4619-18-5)¹HNMR

4619-18-5(4-(4-Chlorophenyl)butanoic acid)Related Search:

3-(4-Chlorobenzoyl)propionic acid 3-(P-CHLOROBENZOYL)-BUTYRIC ACID 4-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)-4-OXOBUTANOIC ACID ETHYL 2-ACETYL-4-(4-CHLOROPHENYL)-4-OXOBUTANOATE 3-BROMO-4-(4-CHLORO-PHENYL)-4-OXO-BUTYRIC ACID

METHYL 4-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)-4-OXOBUTANOATE 4-(2,4-DICHLOROPHENYL)-4-OXOBUTYRIC ACID 2-(3-chlorophenyl)-4-(4-chlorophenyl)-4-oxobutanoic acid 4-(4-CHLORO-PHENYL)-4-OXO-BUTYRIC ACID ETHYL ESTER 4-(4-CHLOROPHENYL)-2-(2,3-DICHLOROPHENYL)-4-OXOBUTANOIC ACID

METHYL 4-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-4-OXOBUTANOATE 4-(4-CHLOROPHENYL)-2-(3-METHYL-5-OXO-1-PHENYL(2-PYRAZOLIN-4-YL))-4-OXOBUTANOIC ACID 4-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-4-OXOBUTANOIC ACID CLIDANAC METHYL 4-(4-CHLOROPHENYL)-2-(2,3-DICHLOROPHENYL)-4-OXOBUTANOATE

4-(4-CHLOROPHENYL)-2,4-DIOXOBUTANOIC ACID METHYL 2-(3-CHLOROPHENYL)-4-(4-CHLOROPHENYL)-4-OXOBUTANOATE METHYL 4-(4-CHLOROPHENYL)-2-(4-ETHYLPHENYL)-4-OXOBUTANOATE

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4-(4-Chlorophenyl)butanic acid 4-(4-chlorophenyl)butanoic acid(SALTDATA: FREE) Benzenebutanoic acid, 4-chloro- 4-Chlorobenzenebutanoic acid -(4-Chlorophenyl)butanic acid 4-(4-CHLORO-PHENYL)-BUTYRIC ACID 4-(4-chlorophenyl)butanoic acid 4619-18-5