Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 225641-84-9
- Chemical Name:
- Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- tert-Butyl ((1R,3S)-3-hydroxycyclopentyl)carbaMate;(1S,3R)-3-(Boc-amino)cyclopentanol;(3-Hydroxy-cyclopentyl)-carbamic acid tert-butyl ester;tert-Butyl ((1R,3S);-3-hydroxycyclopentyl);tert-butyl (1S,3R)-3-hydroxycyclopentylcarbamate;tert-butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate;Benzoicacid,4-fluoro-,(5-bromo-5-methoxyphenyl)methylester;[(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester;Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB11051327
- Molecular Formula:
- C10H19NO3
- Molecular Weight:
- 201.26
- MDL Number:
- MFCD11226176
- MOL File:
- 225641-84-9.mol
- MSDS File:
- SDS
Product description | Number | Pack Size | Price |
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% | 4256-1-54 | 250mg | $290 |
[(1R,3S)-3-HYDROXYCYCLOPENTYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00% | CCH0030964 | 5MG | $495.34 |
tert-Butyl((1R,3S)-3-hydroxycyclopentyl)carbamate 97.0% | 122499 | 1g | $594 |
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% | 4256-1-54 | 1g | $790 |
Tert-Butyl(1R,3S)-3-Hydroxycyclopentylcarbamate | 4732AQ | 250mg | $213.2 |
More product size |
Boiling point | 320.8±31.0 °C(Predicted) |
---|---|
Density | 1.08±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
pka | 12.27±0.40(Predicted) |
Appearance | Off-white to light yellow Solid |
optical activity | Consistent with structure |
InChI | InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-7-4-5-8(12)6-7/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8+/m1/s1 |
InChIKey | SBUKINULYZANSP-SFYZADRCSA-N |
SMILES | C(OC(C)(C)C)(=O)N[C@@H]1CC[C@H](O)C1 |
CAS DataBase Reference | 225641-84-9 |
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
SynQuest Laboratories | 4256-1-54 | tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% | 225641-84-9 | 250mg | $290 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CCH0030964 | [(1R,3S)-3-HYDROXYCYCLOPENTYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00% | 225641-84-9 | 5MG | $495.34 | 2021-12-16 | Buy |
Matrix Scientific | 122499 | tert-Butyl((1R,3S)-3-hydroxycyclopentyl)carbamate 97.0% | 225641-84-9 | 1g | $594 | 2021-12-16 | Buy |
SynQuest Laboratories | 4256-1-54 | tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% | 225641-84-9 | 1g | $790 | 2021-12-16 | Buy |
AK Scientific | 4732AQ | Tert-Butyl(1R,3S)-3-Hydroxycyclopentylcarbamate | 225641-84-9 | 250mg | $213.2 | 2021-12-16 | Buy |
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production
Uses
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) is carboxylic acid ester organic compounds, which can be used as pharmaceutical intermediates.
Synthesis
![Carbamic acid, [(1S,4R)-4-hydroxy-2-cyclopenten-1-yl]-, 1,1-dimethylethyl](/CAS/GIF/201054-55-9.gif)
201054-55-9
![Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/225641-84-9.gif)
225641-84-9
General procedure for the synthesis of tert-butyl ((1R,3S)-3-hydroxycyclopentyl)carbamate from (1S,4R)-4-cyclopenten-1-ol-2-amino-tert-butyloxycarbonyl: Tert-butyl (1S,4R)-4-hydroxycyclopent-2-enylcarbamate (2.0 g, 10 mmol) was dissolved in methanol (20 mL), and the reaction flask was subjected to three times nitrogen Displacement. 10% Pd/C catalyst (0.2 g, 10%, w/w) was added to the above solution, followed by three displacements with hydrogen. The reaction mixture was stirred at room temperature and hydrogen atmosphere (1 atm) for 14 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated to afford the target product ((1R,3S)-3-hydroxycyclopentyl)carbamic acid tert-butyl ester (1.9 g, yield: 95%).
References
[1] Patent: US2016/200730, 2016, A1. Location in patent: Paragraph 0500; 0501


Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
JIAXING REGEN CHEMICAL CO.,LTD | +8613385739570 | regen_chemical1@163.com | China | 226 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
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- [(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester: Synthesis and Application
- [(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester is a synthetic intermediate.
- Dec 13,2022
View Lastest Price from Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) manufacturers
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2025-10-13 | TERT-BUTYL ((1R,3S)-3-HYDROXYCYCLOPENTYL)CARBAMATE
225641-84-9
|
US $3.00-9.00 / KG | 0.1KG | 99% | g-kg-tons, free sample is available | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- TERT-BUTYL ((1R,3S)-3-HYDROXYCYCLOPENTYL)CARBAMATE
225641-84-9
- US $3.00-9.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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