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Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

CAS No.
225641-84-9
Chemical Name:
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms
tert-Butyl ((1R,3S)-3-hydroxycyclopentyl)carbaMate;(1S,3R)-3-(Boc-amino)cyclopentanol;(3-Hydroxy-cyclopentyl)-carbamic acid tert-butyl ester;tert-Butyl ((1R,3S);-3-hydroxycyclopentyl);tert-butyl (1S,3R)-3-hydroxycyclopentylcarbamate;tert-butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate;Benzoicacid,4-fluoro-,(5-bromo-5-methoxyphenyl)methylester;[(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester;Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester
CBNumber:
CB11051327
Molecular Formula:
C10H19NO3
Molecular Weight:
201.26
MDL Number:
MFCD11226176
MOL File:
225641-84-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% 4256-1-54 250mg $290
[(1R,3S)-3-HYDROXYCYCLOPENTYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00% CCH0030964 5MG $495.34
tert-Butyl((1R,3S)-3-hydroxycyclopentyl)carbamate 97.0% 122499 1g $594
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% 4256-1-54 1g $790
Tert-Butyl(1R,3S)-3-Hydroxycyclopentylcarbamate 4732AQ 250mg $213.2
More product size

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Properties

Boiling point 320.8±31.0 °C(Predicted)
Density 1.08±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 12.27±0.40(Predicted)
Appearance Off-white to light yellow Solid
optical activity Consistent with structure
InChI InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-7-4-5-8(12)6-7/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8+/m1/s1
InChIKey SBUKINULYZANSP-SFYZADRCSA-N
SMILES C(OC(C)(C)C)(=O)N[C@@H]1CC[C@H](O)C1
CAS DataBase Reference 225641-84-9

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
SynQuest Laboratories 4256-1-54 tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% 225641-84-9 250mg $290 2021-12-16 Buy
American Custom Chemicals Corporation CCH0030964 [(1R,3S)-3-HYDROXYCYCLOPENTYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER 95.00% 225641-84-9 5MG $495.34 2021-12-16 Buy
Matrix Scientific 122499 tert-Butyl((1R,3S)-3-hydroxycyclopentyl)carbamate 97.0% 225641-84-9 1g $594 2021-12-16 Buy
SynQuest Laboratories 4256-1-54 tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate 97.0% 225641-84-9 1g $790 2021-12-16 Buy
AK Scientific 4732AQ Tert-Butyl(1R,3S)-3-Hydroxycyclopentylcarbamate 225641-84-9 250mg $213.2 2021-12-16 Buy
Product number Packaging Price Buy
4256-1-54 250mg $290 Buy
CCH0030964 5MG $495.34 Buy
122499 1g $594 Buy
4256-1-54 1g $790 Buy
4732AQ 250mg $213.2 Buy

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production

Uses

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) is carboxylic acid ester organic compounds, which can be used as pharmaceutical intermediates.

Synthesis

Carbamic acid, [(1S,4R)-4-hydroxy-2-cyclopenten-1-yl]-, 1,1-dimethylethyl

201054-55-9

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

225641-84-9

General procedure for the synthesis of tert-butyl ((1R,3S)-3-hydroxycyclopentyl)carbamate from (1S,4R)-4-cyclopenten-1-ol-2-amino-tert-butyloxycarbonyl: Tert-butyl (1S,4R)-4-hydroxycyclopent-2-enylcarbamate (2.0 g, 10 mmol) was dissolved in methanol (20 mL), and the reaction flask was subjected to three times nitrogen Displacement. 10% Pd/C catalyst (0.2 g, 10%, w/w) was added to the above solution, followed by three displacements with hydrogen. The reaction mixture was stirred at room temperature and hydrogen atmosphere (1 atm) for 14 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated to afford the target product ((1R,3S)-3-hydroxycyclopentyl)carbamic acid tert-butyl ester (1.9 g, yield: 95%).

References

[1] Patent: US2016/200730, 2016, A1. Location in patent: Paragraph 0500; 0501

201054-55-9
225641-84-9
Synthesis of Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) from Carbamic acid, [(1S,4R)-4-hydroxy-2-cyclopenten-1-yl]-, 1,1-dimethylethyl

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Global( 80)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Accela ChemBio Inc.
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Alchem Pharmtech,Inc.
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JIAXING REGEN CHEMICAL CO.,LTD
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Career Henan Chemica Co
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Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58

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View Lastest Price from Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TERT-BUTYL ((1R,3S)-3-HYDROXYCYCLOPENTYL)CARBAMATE pictures 2025-10-13 TERT-BUTYL ((1R,3S)-3-HYDROXYCYCLOPENTYL)CARBAMATE
225641-84-9
US $3.00-9.00 / KG 0.1KG 99% g-kg-tons, free sample is available ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Spectrum

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) tert-butyl (1S,3R)-3-hydroxycyclopentylcarbamate tert-Butyl ((1R,3S)-3-hydroxycyclopentyl)carbaMate Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester tert-butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate tert-Butyl ((1R,3S) (3-Hydroxy-cyclopentyl)-carbamic acid tert-butyl ester [(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester Carbamic acid, N-[(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (1S,3R)-3-(Boc-amino)cyclopentanol -3-hydroxycyclopentyl) Benzoicacid,4-fluoro-,(5-bromo-5-methoxyphenyl)methylester 225641-84-9 N-BOC