Gatifloxacinacid
- CAS No.
- 121577-32-0
- Chemical Name:
- Gatifloxacinacid
- Synonyms
- Gatifloxacinacid;AM 1155 hydrochloride;PD 135432 hydrochloride);BMS-206584 (hydrochloride);BMS 206584-01 hydrochloride;Gatifloxacin hydrochloride (Standard);Gatifloxacin hydrochloride, 10 mM in DMSO;Gatifloxacin hydrochloride (AM 1155 hydrochloride;AM 1155 HYDROCHLORIDE;BMS 206584-01 HYDROCHLORIDE;PD 135432 HYDROCHLORIDE;3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-,hydrochloride (1:1)
- CBNumber:
- CB11074612
- Molecular Formula:
- C19H22FN3O4.ClH
- Molecular Weight:
- 411.859
- MDL Number:
- MFCD09838901
- MOL File:
- 121577-32-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Gatifloxacin hydrochloride | WEA57732 | 10g | $1147.7 |
| Gatifloxacin hydrochloride | WEA57732 | 25g | $1871.25 |
| Gatifloxacin (hydrochloride) 99.89% | CS-1842 | 500mg | $54 |
| Gatifloxacin (hydrochloride) 99.89% | CS-1842 | 1g | $65 |
| Gatifloxacin (hydrochloride) 99.89% | CS-1842 | 5g | $130 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Powder |
| color | White to off-white |
| FDA UNII | C3J4S9UD4E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
Gatifloxacinacid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | WEA57732 | Gatifloxacin hydrochloride | 121577-32-0 | 10g | $1147.7 | 2026-06-05 | Buy |
| Biosynth | WEA57732 | Gatifloxacin hydrochloride | 121577-32-0 | 25g | $1871.25 | 2026-06-05 | Buy |
| ChemScene | CS-1842 | Gatifloxacin (hydrochloride) 99.89% | 121577-32-0 | 500mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-1842 | Gatifloxacin (hydrochloride) 99.89% | 121577-32-0 | 1g | $65 | 2026-06-04 | Buy |
| ChemScene | CS-1842 | Gatifloxacin (hydrochloride) 99.89% | 121577-32-0 | 5g | $130 | 2026-06-04 | Buy |
Gatifloxacinacid Chemical Properties,Uses,Production
Uses
Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml)[1]. Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
Biological Activity
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a potent fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.
in vivo
Gatifloxacin hydrochloride (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis .
< p>| Animal Model: | Female BALB/c mice with Nocardia brasiliensis in the right hind footpad |
| Dosage: | 100 mg/kg |
| Administration: | Subcutaneous injection; 3 times a day; 30 days |
| Result: | Reduced the production of lesions in mice. |
target
| Topoisomerase II 36.7 μM () |
IC 50
Quinolone; Topoisomerase II: 36.7 μM ()
References
[1] Takei M, et al. Inhibitory activities of Gatifloxacin hydrochloride (AM-1155), a newly developed fluoroquinolone, against bacterial and mammalian type II topoisomerases.Antimicrob Agents Chemother.1998 Oct;42(10):2678-81. DOI:10.1128/AAC.42.10.2678
[2] Fukuda H, et al. Antibacterial activity of Gatifloxacin hydrochloride (AM-1155, CG5501, BMS-206584), a newly developed fluoroquinolone, against sequentially acquired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus. Antimicrob Agents Chemother.1998 Aug;42(8):1917-22. DOI:10.1128/AAC.42.8.1917
[3] Yamada C, et al. Gatifloxacin hydrochlorideacutelystimulatesinsulinsecretionandchronicallysuppressesinsulinbiosynthesis. Eur J Pharmacol.2006 Dec 28;553(1-3):67-72. Epub 2006 Sep 28. DOI:10.1016/j.ejphar.2006.09.043
[4] Daw-Garza A, et al. InvivotherapeuticeffectofGatifloxacin mesylateonBALB/cmiceinfectedwithNocardiabrasiliensis.Antimicrob Agents Chemother.2008 Apr;52(4):1549-50. DOI:10.1128/AAC.00148-08
Gatifloxacinacid Preparation Products And Raw materials
Raw materials
Preparation Products
Gatifloxacinacid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6290 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57473 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40048 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +86-13382787392 | sales@aeechem.com | China | 10002 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
View Lastest Price from Gatifloxacinacid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Gatifloxacin hydrochloride
121577-32-0
|
$34.00 | 99.89% | 10g | TargetMol Chemicals Inc. |
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- Gatifloxacin hydrochloride
121577-32-0
- $34.00
- 99.89%
- TargetMol Chemicals Inc.
