L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]-
- CAS No.
- 1616727-22-0
- Chemical Name:
- L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]-
- Synonyms
- Mc-Val-Cit-PAB-NH-C2-NH-Boc;L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]-
- CBNumber:
- CB110810982
- Molecular Formula:
- C36H54N8O10
- Molecular Weight:
- 758.86
- MDL Number:
- MOL File:
- 1616727-22-0.mol
- MSDS File:
- SDS
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- Properties
| Boiling point | 1035.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.248±0.06 g/cm3(Predicted) |
| pka | 12.11±0.46(Predicted) |
| form | Solid |
| color | White to off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0311347 | MC-Val-Cit-PAB-NH-C2-NH-Boc 95.0% | 1616727-22-0 | 5mg | $422 | 2026-06-04 | Buy |
| ChemScene | CS-0311347 | MC-Val-Cit-PAB-NH-C2-NH-Boc 95.0% | 1616727-22-0 | 10mg | $677 | 2026-06-04 | Buy |
| ChemScene | CS-0311347 | MC-Val-Cit-PAB-NH-C2-NH-Boc 95.0% | 1616727-22-0 | 25mg | $1354 | 2026-06-04 | Buy |
| ChemScene | CS-0311347 | MC-Val-Cit-PAB-NH-C2-NH-Boc 95.0% | 1616727-22-0 | 50mg | $2167 | 2026-06-04 | Buy |
| ChemScene | CS-0311347 | MC-Val-Cit-PAB-NH-C2-NH-Boc 95.0% | 1616727-22-0 | 100mg | $3467 | 2026-06-04 | Buy |
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- Chemical Properties, Uses, Production
Uses
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Biological Activity
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
IC 50
Protease Cleavable Linker; Cleavable Linker
References
[1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 811 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2447 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 1846 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Rane Chemical Co., Ltd. | +86-18738066252 | info@ranechem.com | China | 2999 | 58 |
| Jiangxi Youken Biotechnology Co., Ltd. | 15107073929 | 1150046738@qq.com | China | 464 | 58 |
| ChemExpress | +86-021-58950125 | info@chemexpress.com | China | 790 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(10,10-dimethyl-3,8-dioxo-2,9-dioxa-4,7-diazaundec-1-yl)phenyl]- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | MC-Val-Cit-PAB-NH-C2-NH-Boc
1616727-22-0
|
10g | TargetMol Chemicals Inc. |
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- MC-Val-Cit-PAB-NH-C2-NH-Boc
1616727-22-0
- TargetMol Chemicals Inc.





