2,5-Difluoro-4-(hydrazino)-benzonitrile
- CAS No.
- 129946-63-0
- Chemical Name:
- 2,5-Difluoro-4-(hydrazino)-benzonitrile
- Synonyms
- 4-Cyano-2,5-difluorophenylhydrazine;2,5-Difluoro-4-hydrazinylbenzonitrile;Benzonitrile, 2,5-difluoro-4-hydrazinyl-;2,5-Difluoro-4-hydrazinobenzonitrile 95+%
- CBNumber:
- CB11116859
- Molecular Formula:
- C7H5F2N3
- Molecular Weight:
- 169.13
- MDL Number:
- MFCD04972812
- MOL File:
- 129946-63-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| HazardClass | IRRITANT |
| HS Code | 2928009090 |
2,5-Difluoro-4-(hydrazino)-benzonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS117825 | 2,5-Difluoro-4-hydrazinylbenzonitrile 95% | 129946-63-0 | 250mg | $106 | 2026-06-04 | Buy |
| Activate Scientific | AS117825 | 2,5-Difluoro-4-hydrazinylbenzonitrile 95% | 129946-63-0 | 1g | $228 | 2026-06-04 | Buy |
| Activate Scientific | AS117825 | 2,5-Difluoro-4-hydrazinylbenzonitrile 95% | 129946-63-0 | 5g | $695 | 2026-06-04 | Buy |
| Matrix Scientific | 059557 | 2,5-Difluoro-4-hydrazinylbenzonitrile | 129946-63-0 | 500.00mg | $262 | 2026-05-18 | Buy |
| Matrix Scientific | 059557 | 2,5-Difluoro-4-hydrazinylbenzonitrile | 129946-63-0 | 1.00g | $328 | 2026-05-18 | Buy |
2,5-Difluoro-4-(hydrazino)-benzonitrile Chemical Properties, Uses, Production
Synthesis
98349-22-5
129946-63-0
General procedure for the synthesis of 2,5-difluoro-4-hydrazinylbenzonitrile from 2,4,5-trifluorobenzonitrile: 2,4,5-trifluorobenzonitrile (1 g, 6.3 mmol) was dissolved in hydrazine hydrate (610 mg, 19 mmol) in 1,4-dioxane (3 mL), and the reaction was stirred for 16 hours at room temperature. Upon completion of the reaction, the reaction mixture was extracted by partitioning between ethyl acetate (30 mL) and saturated aqueous sodium bicarbonate (20 mL). The organic layer was separated, washed with saturated aqueous sodium chloride solution (10 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford 4-hydrazino-2,5-difluorobenzonitrile (1.012 g, 93% yield) as a white solid.LC-MS analysis showed m/z (M+H)+ of 170.0.1H-NMR (400 MHz, DMSO-d6) δ (ppm): 4.41 (2H, broad peak), 6.93 (1H, double peak), 7.51 (1H, double peak), 8.22 (1H, broad peak).
References
[1] Patent: US2008/269193, 2008, A1. Location in patent: Page/Page column 40
[2] Patent: US5006148, 1991, A
[3] Patent: US6906006, 2005, B1
2,5-Difluoro-4-(hydrazino)-benzonitrile Preparation Products And Raw materials
2,5-Difluoro-4-(hydrazino)-benzonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6959 | 55 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
