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Goralatide

CAS No.
120081-14-3
Chemical Name:
Goralatide
Synonyms
L-Proline, N-acetyl-L-seryl-L-α-aspartyl-L-lysyl-;Goralatide, Hematopoietic progenitor cell cycle inhibitor
CBNumber:
CB11116884
Molecular Formula:
C20H33N5O9
Molecular Weight:
487.5
MDL Number:
MOL File:
120081-14-3.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:35

Goralatide Properties

Boiling point 992.0±65.0 °C(Predicted)
Density 1.382±0.06 g/cm3(Predicted)
pka 3.39±0.20(Predicted)
FDA UNII H041538E9P

Goralatide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FA73635 Ac-S-D-K-P 120081-14-3 1mg $65 2021-12-16 Buy
Biosynth FA73635 Ac-S-D-K-P 120081-14-3 2mg $113 2021-12-16 Buy
Biosynth FA73635 Ac-S-D-K-P 120081-14-3 5mg $226 2021-12-16 Buy
Biosynth FA73635 Ac-S-D-K-P 120081-14-3 10mg $384 2021-12-16 Buy
Biosynth FA73635 Ac-S-D-K-P 120081-14-3 25mg $768 2021-12-16 Buy
Product number Packaging Price Buy
FA73635 1mg $65 Buy
FA73635 2mg $113 Buy
FA73635 5mg $226 Buy
FA73635 10mg $384 Buy
FA73635 25mg $768 Buy

Goralatide Chemical Properties, Uses, Production

Uses

Goralatide is a compound that regulates the thermal sensitivity of hematopoietic progenitor cells. It can reduce the thermal sensitivity of normal hematopoietic progenitor cells and increase the difference in thermal sensitivity between leukemia progenitor cells and normal progenitor cells, thereby increasing the inhibition window of hyperthermia therapy.

Definition

ChEBI: Goralatide is a tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties. It has a role as an anti-inflammatory agent and a pro-angiogenic agent. It is functionally related to a Ser-Asp-Lys-Pro. It is a conjugate acid of a goralatide(1-).

References

[1] Enhanced selectivity of hyperthermic purging of human progenitor cells using Goralatide, an inhibitor of cell cycle progression DOI:10.1038/sj.bmt.1701045

5497-76-7
120081-14-3
Synthesis of Goralatide from tert-Butyl L-prolinate hydrochloride

Goralatide Preparation Products And Raw materials

Raw materials

Preparation Products

Goralatide Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Hubei kangen Pharmaceutical Chemical Co., Ltd 180-64105258 18064105258 3357312443@qq.com China 695 56
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 Caroline@youngshechem.com China 4726 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-61109150 sales@tcisct.com China 29717 58
Shaoxing Junyu Biotechnology Co., LTD 0571-0571-88211921 19105816207 sales4@gotopbio.com China 5135 58
Phygene 18059081430 2070812664@qq.com China 1232 58
YantaiBio 13758194781; 13758194781 764619768@qq.com China 1755 58
Fuan Bio 15002819872 2845971812@qq.com China 2103 58
Aladdin Scientific tp@aladdinsci.com United States 50068 58
Shaanxi LonierHerb Bio Technology Co Ltd +86-86-+86-86-029-87551862 15002946897 1713330907@QQ.com China 2635 58
L-Proline, N-acetyl-L-seryl-L-α-aspartyl-L-lysyl- Goralatide, Hematopoietic progenitor cell cycle inhibitor 120081-14-3