YK-2-69
- CAS No.
- 2619846-89-6
- Chemical Name:
- YK-2-69
- Synonyms
- YK-2-69;Methanone, [6-[[4-[2-(dimethylamino)-6-benzothiazolyl]-5-fluoro-2-pyrimidinyl]amino]-3-pyridinyl](4-ethyl-1-piperazinyl)-
- CBNumber:
- CB111187292
- Molecular Formula:
- C25H27FN8OS
- Molecular Weight:
- 506.6
- MDL Number:
- MOL File:
- 2619846-89-6.mol
- MSDS File:
- SDS
YK-2-69 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0880232 | YK-2-69 99.44% | 2619846-89-6 | 5mg | $812 | 2026-06-04 | Buy |
| ChemScene | CS-0880232 | YK-2-69 99.44% | 2619846-89-6 | 10mg | $1219 | 2026-06-04 | Buy |
| ChemScene | CS-0880232 | YK-2-69 99.44% | 2619846-89-6 | 25mg | $2080 | 2026-06-04 | Buy |
| ChemScene | CS-0880232 | YK-2-69 99.44% | 2619846-89-6 | 50mg | $2912 | 2026-06-04 | Buy |
| ChemScene | CS-0880232 | YK-2-69 99.44% | 2619846-89-6 | 100mg | $4062 | 2026-06-04 | Buy |
YK-2-69 Chemical Properties, Uses, Production
Description
YK-2-69 is a highly selective DYRK2 inhibitor which specifically interacts with Lys-231 and Lys-234 in the co-crystal structure. Especially, YK-2-69 exhibits more potent anti-PCa efficacy than the first-line drug enzalutamide in vivo.
Uses
YK-2-69 is a highly selective DYRK2 inhibitor with an IC50 value of 9nM. YK-2-69 specifically interacts with Lys-231 and Lys-234 of DYRK2 and can be utilized in researches related to prostate cancer[1].
IC 50
DYRK2: 9 nM (IC50)
References
[1] Yuan K, et al. Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer. Nat Commun. 2022 May 25;13(1):2903. DOI:10.1038/s41467-022-30581-4
YK-2-69 Preparation Products And Raw materials
Raw materials
Preparation Products
YK-2-69 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 964 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Afflon Pharmaceutical (Sichuan) Co., Ltd. | 17336178085 | 1684779048@qq.com | China | 2263 | 58 |
