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Bis(2-mercaptoethyl) sulfone

CAS No.
145626-87-5
Chemical Name:
Bis(2-mercaptoethyl) sulfone
Synonyms
Bis(2-thioethyl) sulphone;2,2'-Sulfonylbis-ethanethiol;2,2'-Sulphonyldiethane-1-thiol;Ethanethiol, 2,2'-sulfonylbis-;Bis(2-mercaptoethyl) sulphone, 2,2'-Sulphonyldiethanethiol
CBNumber:
CB11176170
Molecular Formula:
C4H10O2S3
Molecular Weight:
186.32
MDL Number:
MOL File:
145626-87-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:04:32

Bis(2-mercaptoethyl) sulfone Properties

Melting point 57-58°C
Boiling point 375.6±27.0 °C(Predicted)
Density 1.296±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka pKa (aqueous soln at 25°): 7.9, 9.0
form solid
color Pale yellow
Stability Moisture Sensitive
InChI 1S/C4H10O2S3/c5-9(6,3-1-7)4-2-8/h7-8H,1-4H2
InChIKey YWXCBLUCVBSYNJ-UHFFFAOYSA-N
SMILES [S](=O)(=O)(CCS)CCS
CAS DataBase Reference 145626-87-5
FDA UNII 296JAR8KSL
UNSPSC Code 12352128

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
WGK Germany  WGK 1
HS Code  2930909899
Storage Class 11 - Combustible Solids

Bis(2-mercaptoethyl) sulfone price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological B2186-03 Bis(2-mercaptoethyl) sulfone (BMS) ~90% 145626-87-5 500mg $475 2026-06-03 Buy
Biosynth FB18676 Bis(2-mercaptoethyl)sulfone 145626-87-5 100mg $260 2026-06-04 Buy
Biosynth FB18676 Bis(2-mercaptoethyl)sulfone 145626-87-5 250mg $422.5 2026-06-04 Buy
Biosynth FB18676 Bis(2-mercaptoethyl)sulfone 145626-87-5 500mg $650 2026-06-04 Buy
Biosynth FB18676 Bis(2-mercaptoethyl)sulfone 145626-87-5 1000mg $1040 2026-06-04 Buy
Product number Packaging Price Buy
B2186-03 500mg $475 Buy
FB18676 100mg $260 Buy
FB18676 250mg $422.5 Buy
FB18676 500mg $650 Buy
FB18676 1000mg $1040 Buy

Bis(2-mercaptoethyl) sulfone Chemical Properties, Uses, Production

Chemical Properties

White Crystalline Solid

Uses

Bis(2-mercaptoethyl) sulfone is a useful reagent for the reduction of disulfides in aquous solutions. It is a superior substitute for DTT.

Uses

Reagent for reduction of disulfide bonds in aqueous solutions.

reaction suitability

reagent type: reductant

Purification Methods

BMS recrystallises from hexane as white fluffy crystals. Large amounts are best recrystallised from de-oxygenated H2O (charcoal). It is a good alternative reducing agent to dithiothreitol. Its IR (film) has 2995, 2657, 1306, 1248, 1124 and 729 cm-1 . The synthetic intermediate thioacetate has m 82-83o (white crystals from CCl4). The disulfide is purified by flash chromatography on SiO2 and elution with 50% EtOAc/hexane and recrystallised from hexane, and has m 137-139o. [Lamoureux & Whitesides J Org Chem 58 633 1993, Beilstein 1 IV 2455.]

Bis(2-mercaptoethyl) sulfone Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 21)
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
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Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Nanjing Shizhou Biology Technology Co.,Ltd 18351873721 helen.zhang@synzest.com China 8283 58
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DAYANG CHEM (HANGZHOU) CO.,LTD +86-88938639 +86-17705817739 info@dycnchem.com China 53589 58
Bis(2-thioethyl) sulphone Bis(2-mercaptoethyl) sulphone, 2,2'-Sulphonyldiethanethiol 2,2'-Sulfonylbis-ethanethiol Ethanethiol, 2,2'-sulfonylbis- 2,2'-Sulphonyldiethane-1-thiol 145626-87-5 Metal Isotopes Sulfur & Selenium Compounds