Fenofibrate-d6
- CAS No.
- 1092484-56-4
- Chemical Name:
- Fenofibrate-d6
- Synonyms
- Lipsin-d6; LF 178-d6;Lipirex-d6;Liposit-d6;Nolipax-d6;Lipofene-d6;Lipoclar-d6;Lipantil-d6;MeltDose-d6;Lipanthyl-d6
- CBNumber:
- CB11176332
- Molecular Formula:
- C20H21ClO4
- Molecular Weight:
- 360.83
- MDL Number:
- MOL File:
- 1092484-56-4.mol
- MSDS File:
- SDS
| Melting point | 70-720C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Sightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 1092484-56-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
Fenofibrate-d6 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25710 | Fenofibrate-d6 ≥99%deuteratedforms(d1-d6) | 1092484-56-4 | 500μg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 25710 | Fenofibrate-d6 ≥99%deuteratedforms(d1-d6) | 1092484-56-4 | 1mg | $183 | 2026-04-30 | Buy |
| Cayman Chemical | 25710 | Fenofibrate-d6 ≥99%deuteratedforms(d1-d6) | 1092484-56-4 | 5mg | $753 | 2026-04-30 | Buy |
| TRC | TRC-F248642-1MG | Fenofibrate-d6 >95%(HPLC) | 1092484-56-4 | 1mg | $269 | 2026-06-03 | Buy |
| TRC | TRC-F248642-10MG | Fenofibrate-d6 >95%(HPLC) | 1092484-56-4 | 10mg | $1865 | 2026-06-03 | Buy |
Fenofibrate-d6 Chemical Properties, Uses, Production
Description
Fenofibrate-d6 is intended for use as an internal standard for the quantification of fenofibrate by GC- or LC-MS. Fenofibrate is an agonist of peroxisome proliferator-activated receptor α (PPARα) with EC50 values of 18 and 30 μM for mouse and human receptors, respectively, in a transactivation assay. It is selective for PPARα over PPARγ (EC50s = 300 and 200 μM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at a concentration of 100 μM. In vivo, fenofibrate (50-100 mg/kg) reduces plasma levels of triglycerides, C-reactive protein, and malondialdehyde (MDA) in mice with fructose-induced hypertriglycemia in a dose-dependent manner. It decreases glomerular and tubular atrophy and necrosis induced by cisplatin in rat kidney when administered at a dose of 100 mg/kg. Fenofibrate also reduces the number of pulmonary lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in lung of Tsumura Suzuki obese diabetic (TSOD) mice.
Chemical Properties
White Solid
Uses
Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion.
IC 50
CYP2; CYP3
References
[1] TIMOTHY M. WILLSON. The PPARs: From Orphan Receptors to Drug Discovery[J]. Journal of Medicinal Chemistry, 2000, 43 4: 527-550. DOI: 10.1021/jm990554g
[2] BING SUN. Pleiotropic effects of fenofibrate therapy on rats with hypertriglycemia.[J]. Lipids in Health and Disease, 2015, 14: 27. DOI: 10.1186/s12944-015-0032-3
[3] M. HELMY M E M M Helmy. Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs[J]. PLoS ONE, 2015, 10 1. DOI: 10.1371/journal.pone.0142303
[4] TOSHIYA KUNO. The peroxisome proliferator-activated receptor (PPAR) α agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice.[J]. International Journal of Molecular Sciences, 2014, 15 5: 9160-9172. DOI: 10.3390/ijms15059160
Fenofibrate-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
Fenofibrate-d6 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1949 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3009 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-025-85560043 17301488900 | info@synzest.com | China | 9274 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Yancheng Tongming Biotechnology Co., Ltd. | 15195160625 | 2863565288@qq.com | China | 5178 | 58 |
View Latest Price from Fenofibrate-d6 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Fenofibrate-D6
1092484-56-4
|
1mg | 96% | 50mg | Simson Pharma limited |
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- Fenofibrate-D6
1092484-56-4
- 96%
- Simson Pharma limited
