1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID
![1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID Structure](CAS/GIF/898746-35-5.gif)
- CAS No.
- 898746-35-5
- Chemical Name:
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID
- Synonyms
- 7-Azaindole-6-carboxylic ...;7-AZAINDOLE-6-CARBOXYLIC ACID;1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID
- CBNumber:
- CB1117831
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD08272223
- MOL File:
- 898746-35-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | OR927275 | 100mg | $39 |
| 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | OR927275 | 250mg | $48 |
| 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | OR927275 | 1g | $94 |
| 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | OR927275 | 5g | $453 |
| 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | OR927275 | 100mg | $39 |
| More product size | |||
| Density | 1.506±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | 2-8°C |
| pka | 1.44±0.30(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C8H6N2O2/c11-8(12)6-2-1-5-3-4-9-7(5)10-6/h1-4H,(H,9,10)(H,11,12) |
| InChIKey | LDJMQIKMKHNGDB-UHFFFAOYSA-N |
| SMILES | C12NC=CC1=CC=C(C(O)=O)N=2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR927275 | 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | 898746-35-5 | 100mg | $39 | 2026-06-04 | Buy |
| Apolloscientific | OR927275 | 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | 898746-35-5 | 250mg | $48 | 2026-06-04 | Buy |
| Apolloscientific | OR927275 | 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | 898746-35-5 | 1g | $94 | 2026-06-04 | Buy |
| Apolloscientific | OR927275 | 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | 898746-35-5 | 5g | $453 | 2026-06-04 | Buy |
| Apolloscientific | OR927275 | 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid 95% | 898746-35-5 | 100mg | $39 | 2026-06-04 | Buy |
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID Chemical Properties,Uses,Production
Synthesis
![1H-pyrrolo[2,3-b]pyridine-6-carbonitrile](/CAS/GIF/189882-33-5.gif)
189882-33-5
![1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID](/CAS/GIF/898746-35-5.gif)
898746-35-5
General procedure for the synthesis of 7-azaindole-6-carboxylic acid from 6-cyano-7-azaindole: 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (120 mg, 0.84 mmol) was dissolved in ethanol (10 mL). To the solution was added 6 N sodium hydroxide solution (1.4 mL, 8.4 mmol) and the reaction mixture was stirred at 90 °C for 18 hours. Upon completion of the reaction, the mixture was distilled under reduced pressure to remove the solvent. Subsequently, a 1 N hydrochloric acid solution was added to the residue for acidification. The acidified solution was extracted with ethyl acetate. The organic phases were combined, washed with saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure and purified by column chromatography to afford the target product 7-azaindole-6-carboxylic acid (100 mg, 74% yield). The nuclear magnetic resonance hydrogen spectrum (1H-NMR, 400 MHz, DMSO-d6) data were as follows: δ 12.08 (broad single peak, 1H), 8.11 (double peak, 1H), 7.83 (double peak, 1H), 7.70 (double peak, 1H), 6.58 (double peak, 1H).
References
[1] Patent: WO2014/73904, 2014, A1. Location in patent: Paragraph 942-945
[2] Patent: WO2012/95463, 2012, A1. Location in patent: Page/Page column 80
[3] Patent: CN104387385, 2016, B. Location in patent: Paragraph 0040-0045
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/90bf5659-27a3-42bf-adab-72c68d10d33c.png) |
2019-07-06 | 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID
898746-35-5
|
$500.00 | 1KG | 98% | 1ton | Career Henan Chemical Co |
-
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBOXYLIC ACID
898746-35-5
- $500.00
- 98%
- Career Henan Chemical Co
