ACETYLDIGITOXIN
- CAS No.
- 1111-39-3
- Chemical Name:
- ACETYLDIGITOXIN
- Synonyms
- adicin;a-Form;acylanid;Acedigal;ACETYLDIGITOXIN;Acetildigitoxina;Acetyldigitoxinum;3'''-Acetyldigitoxin;alpha-acetyldigitoxin;acetyl-digitoxin-alpha
- CBNumber:
- CB1117871
- Molecular Formula:
- C43H66O14
- Molecular Weight:
- 806.98
- MDL Number:
- MFCD00151402
- MOL File:
- 1111-39-3.mol
- MSDS File:
- SDS
| Melting point | 217-221° |
|---|---|
| alpha | D20 +5.0° (c = 0.7 in pyridine) |
| Boiling point | 673.84°C (rough estimate) |
| Density | 1.1009 (rough estimate) |
| refractive index | 1.6130 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Chloroform: Slightly Soluble; DMSO: Slightly Soluble; Methanol: Slightly Soluble |
| form | A solid |
| Stability | Hygroscopic |
| FDA UNII | 0ZV4Q4L2FU |
| ATC code | C01AA01 |
ACETYLDIGITOXIN price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 24024 | Acetyldigitoxin ≥95% | 1111-39-3 | 500μg | $185 | 2026-04-30 | Buy |
| Cayman Chemical | 24024 | Acetyldigitoxin ≥95% | 1111-39-3 | 1mg | $333 | 2026-04-30 | Buy |
| TRC | TRC-D445385-1MG | Digitoxin 3'''-Acetate | 1111-39-3 | 1mg | $297 | 2026-06-03 | Buy |
| TRC | TRC-D445385-10MG | Digitoxin 3'''-Acetate | 1111-39-3 | 10mg | $2281 | 2026-06-03 | Buy |
| ChemScene | CS-0006116 | Acetyldigitoxin | 1111-39-3 | 1mg | $720 | 2026-06-04 | Buy |
ACETYLDIGITOXIN Chemical Properties,Uses,Production
Originator
Acylanid ,Sandoz ,US ,1954
Uses
Digitoxin 3'''-Acetate is a derivative of Digitoxin (D445950) which is cardotonic.
Definition
ChEBI: 3'''-O-acetyldigitoxin is a cardenolide glycoside compound consisting of digitoxin having an acetyl substituent at the 3-position on the D-ribo-hexopyranosyl residue at the non-reducing end. It has a role as an anti-arrhythmia drug, a cardiotonic drug and an enzyme inhibitor. It is functionally related to a digitoxin.
Manufacturing Process
Acetyldigitoxin-α can be obtained from acetyldigitoxin-β by heating it in an anhydrous or aqueous organic solvent at neutral, weakly acid or weakly
alkaline pH, i.e., at a pH range from about 3.5 to about 8.
The acetylidigitoxin-β used for this purpose is a cardiac glycoside which can be
obtained either by splitting off the glucose residue from lanatoside A, or by
extraction of the leaves of Digitalis ferrugines. It is composed of the aglycone
digitoxigenin and 3 molecules of digitoxose, to one of which an acetyl group is
attached. Acetyldigitoxin-α, obtained from acetyldigitoxin-β by rearrangement,
differs from the latter in the position of the acetyl group.
The process may be carried out, for example, in the following manner: A
solution of acetyldigitoxin-β in a suitable solvent, such as methanol, is boiled
under reflux and then diluted with water. The unchanged acetyldigitoxin-β,
which crystallizes out first, is filtered off and can again be submitted to the
same process. On concentrating the filtrate, acetyldigitoxin-α separates out in
crystalline form and after filtering off and recrystallizing is obtained in a pure
state. The acetyldigitoxin-α crystallizes from aqueous methanol in platelets
melting at 217-221°C.
brand name
Acylanid (Novartis).
Therapeutic Function
Cardiotonic
Purification Methods
-Acetyldigitoxin is obtained from the commercial mixture [ : (2:1)] [25395-32-8]. The form is obtained from the form by heating in anhydrous or aqueous organic solvent (e.g. aqueous MeOH) at pH 3.5—8. It crystallises from MeOH as plates, CHCl3/Et2O or Me2CO/Et2O. At 20o 1g dissolves in 16mL of MeOH, 66mL of Me2CO and ~880mL of EtOAc. [Stoll & Kreis Helv Chim Acta 35 1318, 1322 1952, Beilstein 18 III/IV 1479.] It is a cardenolide.C5128
ACETYLDIGITOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9983 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81024372 17792795018 | 1053@dideu.com | China | 9999 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Lastest Price from ACETYLDIGITOXIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-10 | Acetyldigitoxin
1111-39-3
|
$693.00 | 10g | TargetMol Chemicals Inc. |
-
- Acetyldigitoxin
1111-39-3
- $693.00
- TargetMol Chemicals Inc.
